PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Han003603

Organism

Helianthus annuus

Taxonomic ID

4232

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Heliantheae alliance; Heliantheae; Helianthus

Family

LSD

Protein Properties

Length: 178aa MW: 18696.8 Da PI: 8.4363

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Han#S32090456	PU_ref	Unigene	View CDS
PUT-169a-Helianthus_annuus-9217	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	40	6.6e-13	7	31	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 C+gCr +L YPrGA++V+CalC++V Han003603 7 CSGCRSILLYPRGASNVCCALCNAV 31 ************************9 PP
2	zf-LSD1	49.6	6.2e-16	46	70	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggCrtlL+Y+rGA+sVRC++C+tV Han003603 46 CGGCRTLLMYTRGATSVRCSCCHTV 70 ************************9 PP
3	zf-LSD1	48.2	1.8e-15	84	107	1	24
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdt 24 Cg+Crt+L+YP+GApsV+Ca+C+ Han003603 84 CGNCRTTLMYPYGAPSVKCAVCQY 107 **********************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	3.7E-13	4	34	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	5.7E-11	7	31	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	1.9E-17	43	72	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	2.7E-13	46	70	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	3.4E-13	81	110	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	2.6E-14	84	108	IPR005735	Zinc finger, LSD1-type

Sequence ? help Back to Top
Protein Sequence Length: 178 aa Download sequence Send to blast
MQSQIVCSGC RSILLYPRGA SNVCCALCNA VTSVPPPGME MDQLICGGCR TLLMYTRGAT 60 SVRCSCCHTV NLAPVANQLA QVNCGNCRTT LMYPYGAPSV KCAVCQYITN VNTSNGRIPV 120 PVRPNGTATS GSMPPVSTPM PPSHNQTVVV ENPMSVDESG KLVSNVVVGV TTEKKAIK

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in cotyledons, roots, rosette leaves, stems, inflorescences and flowers. {ECO:0000269\|PubMed:20456049}.

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023765337.1	1e-112	protein LSD1-like
Refseq	XP_024963805.1	1e-112	protein LSD1-like
Swissprot	P94077	7e-73	LSD1_ARATH; Protein LSD1
TrEMBL	A0A118J7F3	1e-111	A0A118J7F3_CYNCS; Zinc finger, LSD1-type
STRING	XP_007159613.1	3e-99	(Phaseolus vulgaris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G20380.7	1e-74	LSD family protein

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]