PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.069280.1
Common NameCsa_6G318160
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family ERF
Protein Properties Length: 232aa    MW: 25875.2 Da    PI: 7.8207
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.069280.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
             AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56 
                     y+G+r+++ +g+W+AeIrdp++     r++lg+f taeeAa+a+++a+k+++ge
                     9*******.**********954...4**************************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541711.24E-2271128IPR016177DNA-binding domain
PROSITE profilePS5103223.90771128IPR001471AP2/ERF domain
CDDcd000181.15E-3371130No hitNo description
SMARTSM003804.9E-3971134IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.105.4E-3271128IPR001471AP2/ERF domain
PfamPF008473.4E-1572121IPR001471AP2/ERF domain
PRINTSPR003675.1E-127283IPR001471AP2/ERF domain
PRINTSPR003675.1E-1294110IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008219Biological Processcell death
GO:0009723Biological Processresponse to ethylene
GO:0009735Biological Processresponse to cytokinin
GO:0009753Biological Processresponse to jasmonic acid
GO:0010286Biological Processheat acclimation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051707Biological Processresponse to other organism
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0005886Cellular Componentplasma membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 232 aa     Download sequence    Send to blast
3D Structure ? help Back to Top
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A1e-21671271071Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:9159183}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00109PBMTransfer from AT3G16770Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Also induced by cadmium. {ECO:0000269|PubMed:18836139, ECO:0000269|PubMed:9159183}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6819240.0LN681924.1 Cucumis melo genomic scaffold, anchoredscaffold00047.
GenBankLN7132650.0LN713265.1 Cucumis melo genomic chromosome, chr_11.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004153075.21e-173PREDICTED: ethylene-responsive transcription factor RAP2-3-like
SwissprotP427361e-48RAP23_ARATH; Ethylene-responsive transcription factor RAP2-3
TrEMBLA0A0A0KD181e-172A0A0A0KD18_CUCSA; Uncharacterized protein
STRINGXP_004153075.11e-172(Cucumis sativus)
STRINGXP_004173226.11e-172(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G16770.13e-43ethylene-responsive element binding protein
Publications ? help Back to Top
  1. Bueso E, et al.
    The lithium tolerance of the Arabidopsis cat2 mutant reveals a cross-talk between oxidative stress and ethylene.
    Plant J., 2007. 52(6): p. 1052-65
  2. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
  3. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
  4. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
  5. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
  6. Chen YC, et al.
    Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance.
    Sci Rep, 2014. 4: p. 5584
  7. Deslauriers SD,Alvarez AA,Lacey RF,Binder BM,Larsen PB
    Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis.
    New Phytol., 2015. 208(2): p. 442-55
  8. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
  9. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
  10. Liu W, et al.
    Ethylene response factor AtERF72 negatively regulates Arabidopsis thaliana response to iron deficiency.
    Biochem. Biophys. Res. Commun., 2017. 491(3): p. 862-868
  11. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073