PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_8763_iso_5
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family AP2
Protein Properties Length: 573aa    MW: 63156.9 Da    PI: 6.7315
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_8763_iso_5genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP251.23.1e-16293352155
                                  AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                                          s+y+GV++++++gr++A+++d  ++  g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  cra_locus_8763_iso_5_len_2070_ver_3 293 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqtRKgRQVYLGGYDMEEKAARAYDLAALKYWG 352
                                          78*******************988886678446*************************98 PP
2AP246.59.5e-15397446355
                                  AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                                          y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  cra_locus_8763_iso_5_len_2070_ver_3 397 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDIAAIKFRG 446
                                          9***************988532...5************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541712.35E-16293361IPR016177DNA-binding domain
PfamPF008477.5E-13293352IPR001471AP2/ERF domain
CDDcd000182.91E-21293359No hitNo description
PROSITE profilePS5103218.782294360IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.2E-15294360IPR001471AP2/ERF domain
SMARTSM003806.5E-28294366IPR001471AP2/ERF domain
PRINTSPR003671.3E-6295306IPR001471AP2/ERF domain
CDDcd000182.08E-25395456No hitNo description
SuperFamilySSF541719.81E-18395456IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.101.8E-18396454IPR001471AP2/ERF domain
SMARTSM003802.8E-34396460IPR001471AP2/ERF domain
PROSITE profilePS5103219.137396454IPR001471AP2/ERF domain
PfamPF008471.8E-9397446IPR001471AP2/ERF domain
PRINTSPR003671.3E-6436456IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007276Biological Processgamete generation
GO:0010492Biological Processmaintenance of shoot apical meristem identity
GO:0042127Biological Processregulation of cell proliferation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 573 aa     Download sequence    Send to blast
MEVTSSDSSQ PPPQPHHHHF NHQNQSHPPS STATTTTQTS FYSSSSSHFN TSNPLCFGEN  60
TGFHTPLSVM PLKSDGSLCI MEALRRSQTQ VMGPNTSPKL ENFLGGNNPY GSHEREAAVL  120
SLDSIFYSQS VEGPIRQEGN IQVQENHHPY CHGLQHCHDM YQQQANVAEE TNCNNDNVQI  180
PATMSGDELP CLKNWVSHNH VPFNGDHHEL EQHMNNSATM VNDGGAIGCG DLQSLSLSMS  240
PGSQSSCVTA PKHISPTETD CLAIETKKRS SSKVAPKQPV HRKSIDTFGQ RTSQYRGVTR  300
HRWTGRYEAH LWDNSCKKEG QTRKGRQVYL GGYDMEEKAA RAYDLAALKY WGPSTHINFS  360
LENYEQELED MKNMSRQEYV AHLRRKSSGF SRGASMYRGV TRHHQHGRWQ ARIGRVAGNK  420
DLYLGTFSTQ EEAAEAYDIA AIKFRGTSAV TNFDISRYDG KEYAPALAKR NSSTLDQDYN  480
SCASSSSSPH ESLLAITNNN GENHPDELTG MVWSNPQSPK NLGTGGSSSG DPAGMGGGEF  540
GYYSNDQGGN GNGNGNQMVL GNQVPVFALW NEX
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00088SELEXTransfer from AT4G37750Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002510048.20.0AP2-like ethylene-responsive transcription factor ANT
RefseqXP_027092291.10.0AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-146ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A067LBU80.0A0A067LBU8_JATCU; Uncharacterized protein
STRINGVIT_18s0001g08610.t010.0(Vitis vinifera)
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]