PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016494687.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family MYB
Protein Properties Length: 377aa    MW: 42721.6 Da    PI: 6.0705
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016494687.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding49.59.8e-161462148
                     TSSS-HHHHHHHHHHHHHTTTT.-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGgg.tWktIartmgkgRtlkqcksrwqkyl 48
                     +g+W++eEd +l+ ++++ G+g +W + ++++g++R++k+c++rw++yl
   XP_016494687.1 14 KGPWSPEEDTKLKAYIEENGTGnNWIALPQKIGLKRCGKSCRLRWLNYL 62
                     79*********************************************97 PP
2Myb_DNA-binding38.82.1e-1269111246
                      SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      g +T+eEd ++  +    G++ W+ Ia+ ++ gRt++++k++w++
   XP_016494687.1  69 GGFTEEEDNIICSLYISIGSR-WSIIAAQLP-GRTDNDIKNYWNT 111
                      569******************.*********.***********97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129414.304962IPR017930Myb domain
SuperFamilySSF466893.05E-2611109IPR009057Homeodomain-like
SMARTSM007173.6E-121364IPR001005SANT/Myb domain
PfamPF002497.8E-151462IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.607.2E-241569IPR009057Homeodomain-like
CDDcd001671.45E-81662No hitNo description
PROSITE profilePS5129422.10963117IPR017930Myb domain
SMARTSM007172.3E-1167115IPR001005SANT/Myb domain
PfamPF002496.4E-1169111IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.3E-2370117IPR009057Homeodomain-like
CDDcd001679.12E-871111No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0035987Biological Processendodermal cell differentiation
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000021Biological Processregulation of ion homeostasis
GO:2000067Biological Processregulation of root morphogenesis
GO:0048226Cellular ComponentCasparian strip
GO:0000975Molecular Functionregulatory region DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 377 aa     Download sequence    Send to blast
MGRAPCCDKN NVKKGPWSPE EDTKLKAYIE ENGTGNNWIA LPQKIGLKRC GKSCRLRWLN  60
YLRPNIKHGG FTEEEDNIIC SLYISIGSRW SIIAAQLPGR TDNDIKNYWN TRLKKKLLGK  120
RKQSQMNRLL LASSGQDLKE TNGLEENSLL QNLSNSALER LQLHMQLQTL QNPLSFYNNP  180
TLWPKLTPLQ QKMIQTLQPN GLNENQSPIF APINPSDHNQ AHELGQKVVI NEFANTMTNF  240
KANEVEKSNM NNVISSSDNT PIESNNQRNA LDKNIGQENT REIQIQIQGV QGFTQAEIDD  300
LILNKGIGFN TPSENHQIAE FDCFKEMDDG SRDNLAWWSN EFDTNTASSS NSWGSSSNIL  360
QQTEGVYQDY AQGYNLQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A8e-23141177108B-MYB
1h8a_C1e-221411727128MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factors that activates genes required for endodermal differentiation but represses genes involved in proliferative divisions, thus regulating the transition from proliferation to differentiation in root endodermis (PubMed:26371322). Required for Casparian strip formation by positively regulating the expression of the Casparian strip genes CASP1, PER64 and ESB1 and other endodermis-specific genes, thus triggering correct localized lignin biosynthesis in root endodermis and subsequently regulating global ion homeostasis (PubMed:26124109, PubMed:26371322). {ECO:0000269|PubMed:26124109, ECO:0000269|PubMed:26371322}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Directly up-regulated by SCARECROW (SCR), as part of the differentiation program controlled by SHORT-ROOT (SHR). {ECO:0000269|PubMed:24517883, ECO:0000269|PubMed:26371322}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754461e-148HG975446.1 Solanum pennellii chromosome ch07, complete genome.
GenBankHG9755191e-148HG975519.1 Solanum lycopersicum chromosome ch07, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009804259.10.0PREDICTED: myb-related protein 306
RefseqXP_016494687.10.0PREDICTED: transcription factor MYB36-like
SwissprotQ9FKL21e-101MYB36_ARATH; Transcription factor MYB36
TrEMBLA0A1S4C0K80.0A0A1S4C0K8_TOBAC; transcription factor MYB36-like
TrEMBLA0A1U7YYN30.0A0A1U7YYN3_NICSY; myb-related protein 306
STRINGXP_009804259.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA12242154
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G57620.18e-88myb domain protein 36
Publications ? help Back to Top
  1. Fernández-Marcos M, et al.
    Control of Arabidopsis lateral root primordium boundaries by MYB36.
    New Phytol., 2017. 213(1): p. 105-112
    [PMID:27891649]