PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ERF

Protein Properties

Length: 191aa MW: 21614.2 Da PI: 4.8465

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016475341.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	64.7	1.9e-20	54	103	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr+++ +g+++AeIrd s+++ + r++lg+f+taeeAa a+++a+ +l+g XP_016475341.1 54 YRGVRRRP-WGKYAAEIRD-STRN-SVRVWLGTFDTAEEAALAYDQAAFALHG 103 9*****.******.3433.6***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	2.50E-32	52	113	No hit	No description
PROSITE profile	PS51032	23.512	53	111	IPR001471	AP2/ERF domain
Pfam	PF00847	1.5E-14	53	103	IPR001471	AP2/ERF domain
SMART	SM00380	2.8E-37	53	117	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.6E-30	53	111	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	7.85E-24	53	113	IPR016177	DNA-binding domain
PRINTS	PR00367	1.8E-11	54	65	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-11	77	93	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 191 aa Download sequence Send to blast
MDYSQYNHVG FNENDTEDML LLNVLSEAGE NSSNNNLHVN KQETHLKENE GANYRGVRRR 60 PWGKYAAEIR DSTRNSVRVW LGTFDTAEEA ALAYDQAAFA LHGTTAVLNF PVDVVYQSLM 120 EMECGFEEGC SPVLILKKMH SMKKGKSNMN RKKKEKGMSF ENVLVLEDLG ADYLEEILRL 180 SEGYCDPSIS C

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	2e-28	53	114	2	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A	4e-28	50	111	11	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	150	155	RKKKEK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009764919.1	1e-142	PREDICTED: ethylene-responsive transcription factor 1B-like
Refseq	XP_016475341.1	1e-142	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	5e-64	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1S4AFC5	1e-141	A0A1S4AFC5_TOBAC; ethylene-responsive transcription factor 1B-like
TrEMBL	A0A1U7VRB1	1e-141	A0A1U7VRB1_NICSY; ethylene-responsive transcription factor 1B-like
STRING	XP_009764919.1	1e-142	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	5e-42	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]