PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_011080321.1

Organism

Sesamum indicum

Taxonomic ID

4182

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

AP2

Protein Properties

Length: 499aa MW: 54338.3 Da PI: 6.4187

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011080321.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	47.2	5.5e-15	160	219	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + g ++ ++++lg ++ +e+Aa+a++ a++k++g XP_011080321.1 160 SIYRGVTRHRWTGRYEAHLWDnSCRrEGqsRKgRQVYLGGYDKEEKAARAYDLAALKYWG 219 57*****************666664477446***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.04E-22	160	229	No hit	No description
SuperFamily	SSF54171	2.35E-17	160	229	IPR016177	DNA-binding domain
Pfam	PF00847	6.3E-12	160	219	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.256	161	227	IPR001471	AP2/ERF domain
SMART	SM00380	5.8E-30	161	233	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	6.8E-16	161	228	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.0E-6	162	173	IPR001471	AP2/ERF domain
CDD	cd00018	2.99E-14	262	308	No hit	No description
SuperFamily	SSF54171	2.22E-9	262	308	IPR016177	DNA-binding domain
PROSITE profile	PS51032	10.744	263	306	IPR001471	AP2/ERF domain
SMART	SM00380	5.4E-15	263	312	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.2E-6	281	307	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.0E-6	288	308	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000723	Biological Process	telomere maintenance
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0007389	Biological Process	pattern specification process
GO:0010073	Biological Process	meristem maintenance
GO:0010449	Biological Process	root meristem growth
GO:0019827	Biological Process	stem cell population maintenance
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 499 aa Download sequence Send to blast
LPPHLQTPQP HHFSLGLVND NIETPFQNQA YPDWNLINTT QESNEVPKVA DFLGVSKSDS 60 HSELVSYNEI QSTDSDFLFS SNSLVSVQHT LAAAEAATSY DNLQENACNM QQLTLSMGSG 120 KGSTSETSAS GTASADNSNS TSIVEPAPRR TLDTFGQRTS IYRGVTRHRW TGRYEAHLWD 180 NSCRREGQSR KGRQVYLGGY DKEEKAARAY DLAALKYWGT STTTNFPISN YEKELEEMKH 240 MTRQEFVASI RRKSSGFSRG ASMYRGVTRH HQHGRWQARS TEEEAAEAYD IAAIKFRGLN 300 AVTNFDMSRY DVKAILESNT LPIGGGAAKR LKEAQAIDTA GRHQPLLSLQ NQDLSHYSTT 360 QDSSHYQSYI QTQLQLHQQQ PCSYNVNPNH SSSSSSQFYG SYNPVLLHGL MNMGSSSSVM 420 DNNGSSSGSY SGGFLGNGLA MGSGSGSGSG SGGGGSAEEL ALVKVDYDHI PSAAAAYGGW 480 SGETTVQGSN PGVFSMWND

Sequence ? help Back to Top

Protein Sequence Length: 499 aa Download sequence Send to blast

LPPHLQTPQP HHFSLGLVND NIETPFQNQA YPDWNLINTT QESNEVPKVA DFLGVSKSDS  60
HSELVSYNEI QSTDSDFLFS SNSLVSVQHT LAAAEAATSY DNLQENACNM QQLTLSMGSG  120
KGSTSETSAS GTASADNSNS TSIVEPAPRR TLDTFGQRTS IYRGVTRHRW TGRYEAHLWD  180
NSCRREGQSR KGRQVYLGGY DKEEKAARAY DLAALKYWGT STTTNFPISN YEKELEEMKH  240
MTRQEFVASI RRKSSGFSRG ASMYRGVTRH HQHGRWQARS TEEEAAEAYD IAAIKFRGLN  300
AVTNFDMSRY DVKAILESNT LPIGGGAAKR LKEAQAIDTA GRHQPLLSLQ NQDLSHYSTT  360
QDSSHYQSYI QTQLQLHQQQ PCSYNVNPNH SSSSSSQFYG SYNPVLLHGL MNMGSSSSVM  420
DNNGSSSGSY SGGFLGNGLA MGSGSGSGSG SGGGGSAEEL ALVKVDYDHI PSAAAAYGGW  480
SGETTVQGSN PGVFSMWND

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs). {ECO:0000250, ECO:0000269\|PubMed:15454085, ECO:0000269\|PubMed:15635403, ECO:0000269\|PubMed:16424342, ECO:0000269\|PubMed:20190735}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011080321.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin accumulation. {ECO:0000269\|PubMed:15454085}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020550490.1	0.0	LOW QUALITY PROTEIN: AP2-like ethylene-responsive transcription factor PLT2, partial
Swissprot	Q5YGP7	0.0	PLET2_ARATH; AP2-like ethylene-responsive transcription factor PLT2
TrEMBL	A0A2G9HCA3	0.0	A0A2G9HCA3_9LAMI; Uncharacterized protein
STRING	POPTR_0001s05580.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2246	24	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G51190.1	1e-166	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Lee DK,Sieburth LE The bps signal: embryonic arrest from an auxin-independent mechanism in bypass triple mutants. Plant Signal Behav, 2012. 7(6): p. 698-700 [PMID:22580686] Hong LW,Yan DW,Liu WC,Chen HG,Lu YT TIME FOR COFFEE controls root meristem size by changes in auxin accumulation in Arabidopsis. J. Exp. Bot., 2014. 65(1): p. 275-86 [PMID:24277277] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Zhao Q, et al. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche. J Integr Plant Biol, 2014. 56(12): p. 1151-63 [PMID:24831283] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Yang S, et al. The Arabidopsis SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA Targets Directly to PINs and Is Required for Root Stem Cell Niche Maintenance. Plant Cell, 2015. 27(6): p. 1670-80 [PMID:25991732] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Shinohara H,Mori A,Yasue N,Sumida K,Matsubayashi Y Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(14): p. 3897-902 [PMID:27001831] Ou Y, et al. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res., 2016. 26(6): p. 686-98 [PMID:27229312] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis . J Integr Plant Biol, 2017. 59(1): p. 30-43 [PMID:28074634] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]