PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

Trihelix

Protein Properties

Length: 380aa MW: 43260.3 Da PI: 6.3298

Description

Trihelix family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009599397.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	trihelix	78.3	1.2e-24	75	156	2	86
trihelix 2 WtkqevlaLiearremeerlrrgklkkplWeevskkmrergferspkqCkekwenlnkrykkikegekkrtsessstcpyfdqle 86 W ++e++aLi +rre+++ ++++k++k+lW+++s kmre+gf rsp++C++kw+nl k++kk k++++ + s +++y +++e XP_009599397.1 75 WVQEETRALISLRRELDSLFNTSKSNKHLWDQISLKMREKGFDRSPTMCTDKWRNLLKEFKKAKHNQEP---NGSAKMSYHKEIE 156 ****************************************************************99886...5667888988887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	1.4E-4	66	133	IPR009057	Homeodomain-like
PROSITE profile	PS50090	8.711	67	131	IPR017877	Myb-like domain
SMART	SM00717	6.8E-6	71	133	IPR001005	SANT/Myb domain
CDD	cd12203	1.48E-28	73	138	No hit	No description
Pfam	PF13837	2.6E-19	74	158	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0042802	Molecular Function	identical protein binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 380 aa Download sequence Send to blast
MSDKLPTSIN LYEEQESMDQ HSNHMIIEVA APNAHLQQPQ QILLPGISGG DTTSSGGEDN 60 NNNVKLAPKK RAETWVQEET RALISLRREL DSLFNTSKSN KHLWDQISLK MREKGFDRSP 120 TMCTDKWRNL LKEFKKAKHN QEPNGSAKMS YHKEIEEILK ARNKNYKNPT LKVDTFMQFS 180 QKGLDDTSIT FGPVEENGRP TLNLERQLDH DGHPLAITAA DAVTASGSPW NWRETPGNGE 240 QSNSAEGRVI SVKWGDYTKR IGIDGTADAI KQAIKSAFRL RTERAFWLED EQNIVRALDR 300 DMPLGSYSLH VDEGLTIKVC MYEEADHSSV HTEDKTFYTA NDFRDFLSHR GWTCLREYNG 360 YRHVDMLDEL CPGAVYRGVN

Sequence ? help Back to Top

Protein Sequence Length: 380 aa Download sequence Send to blast

MSDKLPTSIN LYEEQESMDQ HSNHMIIEVA APNAHLQQPQ QILLPGISGG DTTSSGGEDN  60
NNNVKLAPKK RAETWVQEET RALISLRREL DSLFNTSKSN KHLWDQISLK MREKGFDRSP  120
TMCTDKWRNL LKEFKKAKHN QEPNGSAKMS YHKEIEEILK ARNKNYKNPT LKVDTFMQFS  180
QKGLDDTSIT FGPVEENGRP TLNLERQLDH DGHPLAITAA DAVTASGSPW NWRETPGNGE  240
QSNSAEGRVI SVKWGDYTKR IGIDGTADAI KQAIKSAFRL RTERAFWLED EQNIVRALDR  300
DMPLGSYSLH VDEGLTIKVC MYEEADHSSV HTEDKTFYTA NDFRDFLSHR GWTCLREYNG  360
YRHVDMLDEL CPGAVYRGVN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2jmw_A	7e-45	69	154	1	86	DNA binding protein GT-1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that binds specifically to the core DNA sequence 5'-GGTTAA-3'. May act as a molecular switch in response to light signals. {ECO:0000269\|PubMed:10437822, ECO:0000269\|PubMed:15044016, ECO:0000269\|PubMed:7866025}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00640	PBM	Transfer from MDP0000164819	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	S46942	0.0	S46942.1 Box II Factor [tobacco, mRNA Partial, 1506 nt].
GenBank	TOBB2F	0.0	M96432.1 Nicotiana tabacum DNA-binding protein (B2F) gene, 3' end.
GenBank	TOBGT1A	0.0	M93436.2 Nicotiana tabacum DNA-binding protein (GT-1a) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009599397.1	0.0	PREDICTED: trihelix transcription factor GT-4 isoform X1
Swissprot	Q9FX53	1e-160	TGT1_ARATH; Trihelix transcription factor GT-1
TrEMBL	Q43326	0.0	Q43326_TOBAC; Box II Factor (Fragment)
TrEMBL	Q7DMS9	0.0	Q7DMS9_TOBAC; DNA-binding protein
STRING	XP_009599397.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5113	21	36

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G13450.1	1e-160	Trihelix family protein

Publications ? help Back to Top
Le Gourrierec J,Li YF,Zhou DX Transcriptional activation by Arabidopsis GT-1 may be through interaction with TFIIA-TBP-TATA complex. Plant J., 1999. 18(6): p. 663-8 [PMID:10417717]