PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009590425.1
Organism
Nicotiana tomentosiformis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family ARR-B
Protein Properties Length: 548aa    MW: 61517.2 Da    PI: 5.508
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009590425.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like81.69e-26193246155
         G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                     k+r+ W+ eLHe+F++av+qL G ++A+Pk+ilelm+v+ L +ehv+SHLQkYRl
  XP_009590425.1 193 KARVLWSAELHEKFLQAVNQL-GMDRAVPKNILELMNVPWLKREHVASHLQKYRL 246
                     689******************.********************************7 PP
2Response_reg81.72.3e-27141221109
                     EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTT CS
    Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaG 93 
                     +l+vdD+p+ +++l+++l+k +y ev+++  +e al ll+e++  ++l++ D+ mp+mdG++ll+ i  e  +lp+i+++a ++ + + +++  G
  XP_009590425.1  14 LLVVDDDPTCLKILEKMLKKCHY-EVTTCNRAEVALSLLRENKngFHLVISDVHMPDMDGFKLLEYIGLEM-DLPVIMMSADDSRNVVMKCVIHG 106
                     599********************.***************999999**********************6654.8********************** PP

                     ESEEEESS--HHHHHH CS
    Response_reg  94 akdflsKpfdpeelvk 109
                     a+d+l Kp+ +e+l +
  XP_009590425.1 107 AHDYLIKPVRIEALKN 122
                     ************9986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363921.6E-1415543IPR017053Response regulator B-type, plant
SuperFamilySSF521722.13E-3411130IPR011006CheY-like superfamily
Gene3DG3DSA:3.40.50.23001.1E-4012135No hitNo description
SMARTSM004482.5E-2912124IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.51213128IPR001789Signal transduction response regulator, receiver domain
PfamPF000723.1E-2415122IPR001789Signal transduction response regulator, receiver domain
CDDcd001565.89E-2915127No hitNo description
SuperFamilySSF466895.02E-18191250IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.4E-26192250IPR009057Homeodomain-like
TIGRFAMsTIGR015572.6E-22193246IPR006447Myb domain, plants
PfamPF002492.3E-7197245IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 548 aa     Download sequence    Send to blast
MYSCSSIKFP TLQLLVVDDD PTCLKILEKM LKKCHYEVTT CNRAEVALSL LRENKNGFHL  60
VISDVHMPDM DGFKLLEYIG LEMDLPVIMM SADDSRNVVM KCVIHGAHDY LIKPVRIEAL  120
KNIWQHVVRK NKDKWKGKVF DQSDTVEDGE WPQEPPEDVE YSSSANEGSL KSSKKRKEED  180
ETEERDDMVA LKKARVLWSA ELHEKFLQAV NQLGMDRAVP KNILELMNVP WLKREHVASH  240
LQKYRLLLKK SMGVSQHQSG LNYSFTGYSE ATFGTPPNGL DLQTLAATIQ LPAQSLATLG  300
PAALSQSATK YSLYVPLVDQ RNHFSFENPK LRFQGQQELN NSNNQVNLLY GIPTAVEPKQ  360
SLRNGIVDNA RGSIYNQASQ AYSAVDFSLN QNMQLRHRGF PASGNSATAT LATKGMLKEE  420
VNSDFRGSRG FSPNDDSFSG LYQQKTQDWR LQNVGSTFDT YIQHGISSLE KSGQNTNAPI  480
AETVLSNEQE TGRVNLMGRS QPNSILGDEP FGQEDLMSAF FEQQQRQNVG PVETAFGDDD  540
DPLDNLPM
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A1e-19190250262ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016450284.10.0PREDICTED: two-component response regulator ARR2-like
SwissprotQ9ZWJ91e-135ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A1S3YDS20.0A0A1S3YDS2_TOBAC; two-component response regulator ARR2-like
STRINGXP_009590424.10.0(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-127response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]