PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT4G16110.1

Common Name

ARP5, ARR2, dl4095w, FCAALL.297, RR2

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ARR-B

Protein Properties

Length: 664aa MW: 72578.1 Da PI: 6.6334

Description

response regulator 2

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT4G16110.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	90.9	1.1e-28	216	269	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 kpr++W+ eLH++Fv av+qL G +kA+Pk+ile+m+v+gLt+e+v+SHLQkYR+ AT4G16110.1 216 KPRVVWSVELHQQFVAAVNQL-GVDKAVPKKILEMMNVPGLTRENVASHLQKYRI 269 79*****************.******************************7 PP
2	Response_reg	77.2	5.8e-26	30	138	1	109
EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTES CS Response_reg 1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGak 95 vl+vdD+p+ +++l+++l y +v+ + +e+al ll++++ +D+++ D+ mp+mdG++ll++ e +lp+i+++a ++++ +l+ + Ga AT4G16110.1 30 VLVVDDDPTCLMILERMLMTCLY-RVTKCNRAESALSLLRKNKngFDIVISDVHMPDMDGFKLLEHVGLEM-DLPVIMMSADDSKSVVLKGVTHGAV 124 89*******************.***********999889******************6644.8******************** PP EEEESS--HHHHHH CS Response_reg 96 dflsKpfdpeelvk 109 d+l Kp+ +e+l + AT4G16110.1 125 DYLIKPVRIEALKN 138 ********9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF036392	3.7E-202	11	656	IPR017053	Response regulator B-type, plant
SuperFamily	SSF52172	9.39E-35	27	151	IPR011006	CheY-like superfamily
Gene3D	G3DSA:3.40.50.2300	1.3E-40	27	177	No hit	No description
SMART	SM00448	6.5E-30	28	140	IPR001789	Signal transduction response regulator, receiver domain
PROSITE profile	PS50110	41.149	29	144	IPR001789	Signal transduction response regulator, receiver domain
Pfam	PF00072	1.5E-22	30	138	IPR001789	Signal transduction response regulator, receiver domain
CDD	cd00156	1.14E-26	31	143	No hit	No description
PROSITE profile	PS51294	11.323	213	272	IPR017930	Myb domain
SuperFamily	SSF46689	7.17E-20	214	273	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	6.1E-30	215	274	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	2.8E-24	216	269	IPR006447	Myb domain, plants
Pfam	PF00249	1.0E-8	218	268	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009736	Biological Process	cytokinin-activated signaling pathway
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0010082	Biological Process	regulation of root meristem growth
GO:0010119	Biological Process	regulation of stomatal movement
GO:0010150	Biological Process	leaf senescence
GO:0071368	Biological Process	cellular response to cytokinin stimulus
GO:0080113	Biological Process	regulation of seed growth
GO:0005634	Cellular Component	nucleus
GO:0000156	Molecular Function	phosphorelay response regulator activity
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000025	anatomy	root tip
PO:0000036	anatomy	leaf vascular system
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000282	anatomy	trichome
PO:0000293	anatomy	guard cell
PO:0005660	anatomy	hydathode
PO:0006079	anatomy	shoot system meristem
PO:0006339	anatomy	juvenile vascular leaf
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025195	anatomy	pollen tube cell
PO:0025281	anatomy	pollen
PO:0001016	developmental stage	L mature pollen stage
PO:0001017	developmental stage	M germinated pollen stage
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 664 aa Download sequence Send to blast
MVNPGHGRGP DSGTAAGGSN SDPFPANLRV LVVDDDPTCL MILERMLMTC LYRVTKCNRA 60 ESALSLLRKN KNGFDIVISD VHMPDMDGFK LLEHVGLEMD LPVIMMSADD SKSVVLKGVT 120 HGAVDYLIKP VRIEALKNIW QHVVRKKRNE WNVSEHSGGS IEDTGGDRDR QQQHREDADN 180 NSSSVNEGNG RSSRKRKEEE VDDQGDDKED SSSLKKPRVV WSVELHQQFV AAVNQLGVDK 240 AVPKKILEMM NVPGLTRENV ASHLQKYRIY LRRLGGVSQH QGNMNHSFMT GQDQSFGPLS 300 SLNGFDLQSL AVTGQLPPQS LAQLQAAGLG RPTLAKPGMS VSPLVDQRSI FNFENPKIRF 360 GDGHGQTMNN GNLLHGVPTG SHMRLRPGQN VQSSGMMLPV ADQLPRGGPS MLPSLGQQPI 420 LSSSVSRRSD LTGALAVRNS IPETNSRVLP TTHSVFNNFP ADLPRSSFPL ASAPGISVPV 480 SVSYQEEVNS SDAKGGSSAA TAGFGNPSYD IFNDFPQHQQ HNKNISNKLN DWDLRNMGLV 540 FSSNQDAATA TATAAFSTSE AYSSSSTQRK RRETDATVVG EHGQNLQSPS RNLYHLNHVF 600 MDGGSVRVKS ERVAETVTCP PANTLFHEQY NQEDLMSAFL KQEGIPSVDN EFEFDGYSID 660 NIQV

Sequence ? help Back to Top

Protein Sequence Length: 664 aa Download sequence Send to blast

MVNPGHGRGP DSGTAAGGSN SDPFPANLRV LVVDDDPTCL MILERMLMTC LYRVTKCNRA  60
ESALSLLRKN KNGFDIVISD VHMPDMDGFK LLEHVGLEMD LPVIMMSADD SKSVVLKGVT  120
HGAVDYLIKP VRIEALKNIW QHVVRKKRNE WNVSEHSGGS IEDTGGDRDR QQQHREDADN  180
NSSSVNEGNG RSSRKRKEEE VDDQGDDKED SSSLKKPRVV WSVELHQQFV AAVNQLGVDK  240
AVPKKILEMM NVPGLTRENV ASHLQKYRIY LRRLGGVSQH QGNMNHSFMT GQDQSFGPLS  300
SLNGFDLQSL AVTGQLPPQS LAQLQAAGLG RPTLAKPGMS VSPLVDQRSI FNFENPKIRF  360
GDGHGQTMNN GNLLHGVPTG SHMRLRPGQN VQSSGMMLPV ADQLPRGGPS MLPSLGQQPI  420
LSSSVSRRSD LTGALAVRNS IPETNSRVLP TTHSVFNNFP ADLPRSSFPL ASAPGISVPV  480
SVSYQEEVNS SDAKGGSSAA TAGFGNPSYD IFNDFPQHQQ HNKNISNKLN DWDLRNMGLV  540
FSSNQDAATA TATAAFSTSE AYSSSSTQRK RRETDATVVG EHGQNLQSPS RNLYHLNHVF  600
MDGGSVRVKS ERVAETVTCP PANTLFHEQY NQEDLMSAFL KQEGIPSVDN EFEFDGYSID  660
NIQV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1irz_A	7e-22	212	274	1	63	ARR10-B
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.21955	0.0	floral meristem\| seed\| vegetative tissue

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	245477_at	0.0
Expression Atlas	AT4G16110	-
AtGenExpress	AT4G16110	-
ATTED-II	AT4G16110	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Detected in the whole plant. Predominantly expressed in pollen. {ECO:0000269\|PubMed:11370868, ECO:0000269\|PubMed:15173562, ECO:0000269\|PubMed:9891419}.

Functional Description ? help Back to Top
Source	Description
TAIR	Encodes a pollen-specific transcription factor involved in the expression of nuclear genes for components of mitochondrial complex I in Arabidopsis. Acts in concert with other type-B ARRs in the cytokinin signaling pathway. AHK3 mediates cytokinin-induced phosphorylation of ARR2 on the Asp-80 residue. This phosphorylation plays a positive role of ARR2 in cytokinin-mediated control of leaf longevity.
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269\|PubMed:11370868, ECO:0000269\|PubMed:11574878, ECO:0000269\|PubMed:15282545, ECO:0000269\|PubMed:16407152}.

Function -- GeneRIF ? help Back to Top
identification of the Arabidopsis response regulator 2 (ARR2) as a signalling component functioning downstream of ETR1 in ethylene signal transduction [ARR2] [PMID: 15282545] Transgenic overexpression of wild-type, but not an unphosphorylatable mutant ARR2, led to delayed senescence of leaves. [PMID: 16407152] Results show that cytokinins modulate salicylic acid signaling to augment resistance against Pst, a process in which the interaction between NPR1/TGA3 and ARR2 is important. [PMID: 20708590] Cytokinin facilitates the degradation of ARR2 protein. [PMID: 22050482] Cytokinin-facilitated degradation of ARR2 must be appreciated as a post-translational event important for regulating cytokinin signaling intensity. [PMID: 22751310] Data indicate that one of the immediate early cytokinin response genes is ARR6, which has been shown to be a direct target gene of ARR1, ARR2 and other type-B ARRs. [PMID: 23620480] Data suggest that shoot removal induces the quantitative and qualitative development of chloroplasts in roots, with cytokinin signaling via RESPONSE REGULATOR (ARR)-ARR1 and ARR12 functioning downstream of wounding signaling to up-regulate genes associated with chloroplast development. [PMID: 28193764] ARR2 directly activates the expression of PRX33 and PRX34, which are required for SA- and PAMP-triggered ROS production. Thus, the CK signaling pathway regulates ROS homeostasis in guard cells, which leads to enhanced stomatal immunity and plant resistance to bacteria. [PMID: 28254779] Cytokinins promote actin bundling and the resultant second rapid cell elongation through activating the signaling pathway involving the cytokinin receptors ARABIDOPSIS HISTIDINE KINASE3 (AHK3) and AHK4 and the B-type transcription factor ARABIDOPSIS RESPONSE REGULATOR2. [PMID: 30185441]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00054	PBM	25215497	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT4G16110.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT3G23240(A), AT5G62920(A)

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	cytokinin, ethylene

Interaction ? help Back to Top
Source	Intact With
IntAct	Search Q9ZWJ9

Phenotype -- Disruption Phenotype ? help Back to Top
Source	Description
UniProt	DISRUPTION PHENOTYPE: Retarded growth and development, and early flowering. Reduced responses to ethylene and cytokinin. {ECO:0000269\|PubMed:15282545}.

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT4G16110

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK175737	0.0	AK175737.1 Arabidopsis thaliana mRNA for hypothetical protein, complete cds, clone: RAFL22-28-G07.
GenBank	AK175959	0.0	AK175959.1 Arabidopsis thaliana mRNA for hypothetical protein, complete cds, clone: RAFL22-64-J02.
GenBank	AK176614	0.0	AK176614.1 Arabidopsis thaliana mRNA for hypothetical protein, complete cds, clone: RAFL25-13-O13.
GenBank	DQ473519	0.0	DQ473519.1 Arabidopsis thaliana ARR2 (ARR2) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_193346.5	0.0	response regulator 2
Swissprot	Q9ZWJ9	0.0	ARR2_ARATH; Two-component response regulator ARR2
TrEMBL	A0A178USW7	0.0	A0A178USW7_ARATH; Two-component response regulator
STRING	AT4G16110.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2403	27	73
Representative plant	OGRP292	17	120

Link Out ? help Back to Top
Phytozome	AT4G16110.1
Entrez Gene	827297
iHOP	AT4G16110
wikigenes	AT4G16110

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Sakai H,Aoyama T,Oka A Arabidopsis ARR1 and ARR2 response regulators operate as transcriptional activators. Plant J., 2000. 24(6): p. 703-11 [PMID:11135105] Suzuki T,Sakurai K,Ueguchi C,Mizuno T Two types of putative nuclear factors that physically interact with histidine-containing phosphotransfer (Hpt) domains, signaling mediators in His-to-Asp phosphorelay, in Arabidopsis thaliana. Plant Cell Physiol., 2001. 42(1): p. 37-45 [PMID:11158442] Lohrmann J, et al. The response regulator ARR2: a pollen-specific transcription factor involved in the expression of nuclear genes for components of mitochondrial complex I in Arabidopsis. Mol. Genet. Genomics, 2001. 265(1): p. 2-13 [PMID:11370868] Hwang I,Sheen J Two-component circuitry in Arabidopsis cytokinin signal transduction. Nature, 2001. 413(6854): p. 383-9 [PMID:11574878] Haberer G,Kieber JJ Cytokinins. New insights into a classic phytohormone. Plant Physiol., 2002. 128(2): p. 354-62 [PMID:11842139] Hwang I,Chen HC,Sheen J Two-component signal transduction pathways in Arabidopsis. Plant Physiol., 2002. 129(2): p. 500-15 [PMID:12068096] Che P,Gingerich DJ,Lall S,Howell SH Global and hormone-induced gene expression changes during shoot development in Arabidopsis. Plant Cell, 2002. 14(11): p. 2771-85 [PMID:12417700] Imamura A,Kiba T,Tajima Y,Yamashino T,Mizuno T In vivo and in vitro characterization of the ARR11 response regulator implicated in the His-to-Asp phosphorelay signal transduction in Arabidopsis thaliana. Plant Cell Physiol., 2003. 44(2): p. 122-31 [PMID:12610214] Rashotte AM,Carson SD,To JP,Kieber JJ Expression profiling of cytokinin action in Arabidopsis. Plant Physiol., 2003. 132(4): p. 1998-2011 [PMID:12913156] Tajima Y, et al. Comparative studies on the type-B response regulators revealing their distinctive properties in the His-to-Asp phosphorelay signal transduction of Arabidopsis thaliana. Plant Cell Physiol., 2004. 45(1): p. 28-39 [PMID:14749483] Tanaka Y,Suzuki T,Yamashino T,Mizuno T Comparative studies of the AHP histidine-containing phosphotransmitters implicated in His-to-Asp phosphorelay in Arabidopsis thaliana. Biosci. Biotechnol. Biochem., 2004. 68(2): p. 462-5 [PMID:14981318] Mason MG,Li J,Mathews DE,Kieber JJ,Schaller GE Type-B response regulators display overlapping expression patterns in Arabidopsis. Plant Physiol., 2004. 135(2): p. 927-37 [PMID:15173562] Hass C, et al. The response regulator 2 mediates ethylene signalling and hormone signal integration in Arabidopsis. EMBO J., 2004. 23(16): p. 3290-302 [PMID:15282545] Mason MG, et al. Multiple type-B response regulators mediate cytokinin signal transduction in Arabidopsis. Plant Cell, 2005. 17(11): p. 3007-18 [PMID:16227453] Kim HJ, et al. Cytokinin-mediated control of leaf longevity by AHK3 through phosphorylation of ARR2 in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2006. 103(3): p. 814-9 [PMID:16407152] Desikan R, et al. Ethylene-induced stomatal closure in Arabidopsis occurs via AtrbohF-mediated hydrogen peroxide synthesis. Plant J., 2006. 47(6): p. 907-16 [PMID:16961732] Dortay H,Mehnert N,B Analysis of protein interactions within the cytokinin-signaling pathway of Arabidopsis thaliana. FEBS J., 2006. 273(20): p. 4631-44 [PMID:16965536] Ishida K,Yamashino T,Yokoyama A,Mizuno T Three type-B response regulators, ARR1, ARR10 and ARR12, play essential but redundant roles in cytokinin signal transduction throughout the life cycle of Arabidopsis thaliana. Plant Cell Physiol., 2008. 49(1): p. 47-57 [PMID:18037673] Dortay H, et al. Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana. J. Proteome Res., 2008. 7(9): p. 3649-60 [PMID:18642946] Wang Y, et al. Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. Plant Physiol., 2008. 148(3): p. 1201-11 [PMID:18775970] Che P,Lall S,Howell SH Acquiring competence for shoot development in Arabidopsis: ARR2 directly targets A-type ARR genes that are differentially activated by CIM preincubation. Plant Signal Behav, 2008. 3(2): p. 99-101 [PMID:19704721] Choi J, et al. The cytokinin-activated transcription factor ARR2 promotes plant immunity via TGA3/NPR1-dependent salicylic acid signaling in Arabidopsis. Dev. Cell, 2010. 19(2): p. 284-95 [PMID:20708590] Wang Y,Elhiti M,Hebelstrup KH,Hill RD,Stasolla C Manipulation of hemoglobin expression affects Arabidopsis shoot organogenesis. Plant Physiol. Biochem., 2011. 49(10): p. 1108-16 [PMID:21741261] Kim K, et al. Cytokinin-facilitated proteolysis of ARABIDOPSIS RESPONSE REGULATOR 2 attenuates signaling output in two-component circuitry. Plant J., 2012. 69(6): p. 934-45 [PMID:22050482] Choi J, et al. Functional identification of OsHk6 as a homotypic cytokinin receptor in rice with preferential affinity for iP. Plant Cell Physiol., 2012. 53(7): p. 1334-43 [PMID:22642989] Kim K,Hwang I Attenuation of cytokinin signaling via proteolysis of a type-B response regulator. Plant Signal Behav, 2012. 7(7): p. 756-9 [PMID:22751310] Hill K, et al. Functional characterization of type-B response regulators in the Arabidopsis cytokinin response. Plant Physiol., 2013. 162(1): p. 212-24 [PMID:23482873] Ramireddy E,Brenner WG,Pfeifer A,Heyl A,Schm In planta analysis of a cis-regulatory cytokinin response motif in Arabidopsis and identification of a novel enhancer sequence. Plant Cell Physiol., 2013. 54(7): p. 1079-92 [PMID:23620480] Zwack PJ,Rashotte AM Cytokinin inhibition of leaf senescence. Plant Signal Behav, 2013. 8(7): p. e24737 [PMID:23656876] Takahashi N, et al. Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots. Curr. Biol., 2013. 23(18): p. 1812-7 [PMID:24035544] Ge XM, et al. Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis. Plant J., 2015. 82(1): p. 138-50 [PMID:25704455] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Takahashi N,Umeda M Cytokinins promote onset of endoreplication by controlling cell cycle machinery. Plant Signal Behav, 2014. 9(8): p. e29396 [PMID:25763620] Kobayashi K, et al. Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling. Plant Physiol., 2017. 173(4): p. 2340-2355 [PMID:28193764] Arnaud D, et al. Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis. Plant Cell, 2017. 29(3): p. 543-559 [PMID:28254779] Zhang TQ, et al. A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration. Plant Cell, 2017. 29(5): p. 1073-1087 [PMID:28389585] Meng WJ, et al. Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL. Plant Cell, 2017. 29(6): p. 1357-1372 [PMID:28576846] Zhang F,May A,Irish VF Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL. Trends Plant Sci., 2017. 22(10): p. 815-817 [PMID:28886911] Takatsuka H,Higaki T,Umeda M Actin Reorganization Triggers Rapid Cell Elongation in Roots. Plant Physiol., 2018. 178(3): p. 1130-1141 [PMID:30185441] Sakai H,Aoyama T,Bono H,Oka A Two-component response regulators from Arabidopsis thaliana contain a putative DNA-binding motif. Plant Cell Physiol., 1998. 39(11): p. 1232-9 [PMID:9891419]