PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer

Family

C2H2

Protein Properties

Length: 347aa MW: 39432.1 Da PI: 6.9093

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_004510958.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21.1	8.1e-07	186	205	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C+k+F+r nL+ H+ XP_004510958.1 186 FSCPVCSKTFNRYNNLQMHM 205 89*****************9 PP
2	zf-C2H2	16.7	2e-05	270	292	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y C +CgksF k + ++H +++ XP_004510958.1 270 YMCRKCGKSFAVKGDWRTHEKNC 292 89*****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00355	0.031	186	208	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	5.3E-6	186	205	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.762	186	213	IPR007087	Zinc finger, C2H2
Pfam	PF13912	8.1E-5	186	205	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	6.88E-9	186	208	No hit	No description
PROSITE pattern	PS00028	0	188	208	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	6.88E-9	265	290	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.4E-6	266	290	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	30	270	290	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.974	270	290	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 347 aa Download sequence Send to blast
MTDPQSNFFD EWYNFMLLNP HSSSSSSSSN QTNMLSSSSN YPFLHNSNNM YQIQFQHQAS 60 SSTLNPPSPP LREALPLINK LSLKNHQQEN HEPSNINSTT TLEEEEDDHD HDDINDDESV 120 TVALQIGLPR MSNSSCDLGS RMVSNCIEMA EKEELNMVSE HPLERLNKGQ YWIPTPSQIL 180 IGPTQFSCPV CSKTFNRYNN LQMHMWGHGS QYRKGPDSLK GTQPTAMLRL PCFCCAQGCK 240 HNIDHPRAKP LKDFRTLQTH YKRKHGIKPY MCRKCGKSFA VKGDWRTHEK NCGKIWYCLC 300 GSDFKHKRSL KDHIKAFGYG HGAFGIDCLQ EEDEVGSEIE HDGGSSV

Sequence ? help Back to Top

Protein Sequence Length: 347 aa Download sequence Send to blast

MTDPQSNFFD EWYNFMLLNP HSSSSSSSSN QTNMLSSSSN YPFLHNSNNM YQIQFQHQAS  60
SSTLNPPSPP LREALPLINK LSLKNHQQEN HEPSNINSTT TLEEEEDDHD HDDINDDESV  120
TVALQIGLPR MSNSSCDLGS RMVSNCIEMA EKEELNMVSE HPLERLNKGQ YWIPTPSQIL  180
IGPTQFSCPV CSKTFNRYNN LQMHMWGHGS QYRKGPDSLK GTQPTAMLRL PCFCCAQGCK  240
HNIDHPRAKP LKDFRTLQTH YKRKHGIKPY MCRKCGKSFA VKGDWRTHEK NCGKIWYCLC  300
GSDFKHKRSL KDHIKAFGYG HGAFGIDCLQ EEDEVGSEIE HDGGSSV

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_004510958.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT135770	1e-172	BT135770.1 Medicago truncatula clone JCVI-FLMt-15M3 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004510958.1	0.0	zinc finger protein WIP2-like
Refseq	XP_004510959.1	0.0	zinc finger protein WIP2-like
Swissprot	Q9SVY1	1e-125	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	A0A1S2YWC0	0.0	A0A1S2YWC0_CICAR; zinc finger protein WIP2-like
STRING	XP_004510958.1	0.0	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF170	34	289

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-121	C2H2 family protein

Publications ? help Back to Top
Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]