PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum

Family

C2H2

Protein Properties

Length: 427aa MW: 46645.3 Da PI: 8.7183

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Traes_5DL_51643AC9F.1	genome	IWGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.8	3.9e-05	264	283	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C k+F+r n++ H+ Traes_5DL_51643AC9F.1 264 FSCPVCFKTFNRYNNMQMHM 283 89*****************9 PP
2	zf-C2H2	11	0.0014	345	365	3	23
ETTTTEEESSHHHHHHHHHHT CS zf-C2H2 3 CpdCgksFsrksnLkrHirtH 23 C Cgk F k + ++H +++ Traes_5DL_51643AC9F.1 345 CRRCGKAFAVKGDWRTHEKNC 365 *****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	6.4E-6	264	283	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	5.32E-7	264	286	No hit	No description
PROSITE profile	PS50157	9.64	264	291	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	266	286	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	5.32E-7	338	363	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.9E-4	341	363	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	8.538	343	363	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 427 aa Download sequence Send to blast
HKLSSQAWEA RSRSASYPEL EPWRTRTRPS SRTTNSTATT SHPRRCRRQW RPRRRLLRSP 60 PTPPAPSSPR RLLLPXXXXX XLREALPLLS LAPASRRSRE RRSGPGPDDS DDGDEEDGEE 120 GKQAPGPAAS SSLHHNQQLA GRQLFADLNS KATDDAMDSE AGGAAGDVTV ALHIGLPSAG 180 TAAGLISGIS AAARAARDDE EEEDDRVSRE LSGGGAEGDG DDDGENEAAV APVLGFASTP 240 IGRLNKGQYW IPTPTQILIG PTQFSCPVCF KTFNRYNNMQ MHMWGHGSQY RKGPESLRGI 300 QPTAMLRLPC YCCAPGCRNN VDHPRAXXXX XTHYKRKHGL KPFLCRRCGK AFAVKGDWRT 360 HEKNCGKLWY CLCGSEFKHK RSLKDHARAF GQGHGALGGA GLDDDDDCAV SDVXXXXXXX 420 XVAARSP

Sequence ? help Back to Top

Protein Sequence Length: 427 aa Download sequence Send to blast

HKLSSQAWEA RSRSASYPEL EPWRTRTRPS SRTTNSTATT SHPRRCRRQW RPRRRLLRSP  60
PTPPAPSSPR RLLLPXXXXX XLREALPLLS LAPASRRSRE RRSGPGPDDS DDGDEEDGEE  120
GKQAPGPAAS SSLHHNQQLA GRQLFADLNS KATDDAMDSE AGGAAGDVTV ALHIGLPSAG  180
TAAGLISGIS AAARAARDDE EEEDDRVSRE LSGGGAEGDG DDDGENEAAV APVLGFASTP  240
IGRLNKGQYW IPTPTQILIG PTQFSCPVCF KTFNRYNNMQ MHMWGHGSQY RKGPESLRGI  300
QPTAMLRLPC YCCAPGCRNN VDHPRAXXXX XTHYKRKHGL KPFLCRRCGK AFAVKGDWRT  360
HEKNCGKLWY CLCGSEFKHK RSLKDHARAF GQGHGALGGA GLDDDDDCAV SDVXXXXXXX  420
XVAARSP

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK356814	0.0	AK356814.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv1040D10.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020180661.1	1e-176	zinc finger protein WIP2-like
Swissprot	Q9SVY1	1e-114	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	A0A3B6LP54	0.0	A0A3B6LP54_WHEAT; Uncharacterized protein
TrEMBL	A0A446UDH7	0.0	A0A446UDH7_TRITD; Uncharacterized protein
STRING	Traes_5DL_51643AC9F.1	0.0	(Triticum aestivum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP586	38	170

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-102	C2H2 family protein

Publications ? help Back to Top
Brenchley R, et al. Analysis of the bread wheat genome using whole-genome shotgun sequencing. Nature, 2012. 491(7426): p. 705-10 [PMID:23192148] Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]