PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

HD-ZIP

Protein Properties

Length: 324aa MW: 34813.6 Da PI: 8.4228

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10001549m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	55.7	8.3e-18	157	211	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++keq +Lee F+++ +++ +++ LA++l+L +rqV vWFqNrRa+ k Thhalv10001549m 157 RKKLRLSKEQAVVLEETFKEHTTLNPKQKLALARQLNLRTRQVEVWFQNRRARTK 211 788899***********************************************98 PP
2	HD-ZIP_I/II	123.8	7.9e-40	157	246	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rlskeq+ +LEe+F+e+++L+p++K +lar+L+l++rqv+vWFqnrRARtk+kq+E+d+e+Lkr++d+l+een+rL+kev+eLr +l Thhalv10001549m 157 RKKLRLSKEQAVVLEETFKEHTTLNPKQKLALARQLNLRTRQVEVWFQNRRARTKLKQTEVDCEYLKRCCDNLTEENRRLHKEVSELR-AL 246 69*************************************************************************************9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	3.2E-32	1	117	IPR006712	HD-ZIP protein, N-terminal
Gene3D	G3DSA:1.10.10.60	2.1E-19	137	211	IPR009057	Homeodomain-like
SuperFamily	SSF46689	1.5E-18	141	214	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.167	153	213	IPR001356	Homeobox domain
SMART	SM00389	1.4E-14	155	217	IPR001356	Homeobox domain
Pfam	PF00046	2.3E-15	157	211	IPR001356	Homeobox domain
CDD	cd00086	9.28E-14	157	214	No hit	No description
PROSITE pattern	PS00027	0	188	211	IPR017970	Homeobox, conserved site
SMART	SM00340	2.5E-26	213	256	IPR003106	Leucine zipper, homeobox-associated
Pfam	PF02183	1.3E-11	213	247	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009641	Biological Process	shade avoidance
GO:0009725	Biological Process	response to hormone
GO:0010218	Biological Process	response to far red light
GO:0005634	Cellular Component	nucleus
GO:0009506	Cellular Component	plasmodesma
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 324 aa Download sequence Send to blast
MGERDDGLGL SLSLGFSQQK EPCPRLNLLP LTTSSSSSSF HHMHNHNNNH LQKKIQHNSW 60 PHLFQSSEKN PDAGSFGRGF DVNRAPSAAA VVDLEEDGTG VSSPNSTVSS VSGNKRDLAA 120 ARGGGGDENE GERASCSHGG GSGGSDDEDG GNGDGSRKKL RLSKEQAVVL EETFKEHTTL 180 NPKQKLALAR QLNLRTRQVE VWFQNRRART KLKQTEVDCE YLKRCCDNLT EENRRLHKEV 240 SELRALKLSP HLYMHMTPPT TLTMCPSCER VSASSSSTAV AAPPSSSSAA SGGGGWIPTV 300 VGRPSPQRPT PCAAISLQSR LAH*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	155	161	SRKKLRL
2	205	213	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10001549m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By transition from light to far-red light. {ECO:0000269\|PubMed:8106086}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006397669.1	0.0	homeobox-leucine zipper protein ATHB-4
Swissprot	P92953	1e-151	ATHB4_ARATH; Homeobox-leucine zipper protein ATHB-4
TrEMBL	V4L9T2	0.0	V4L9T2_EUTSA; Uncharacterized protein
STRING	XP_006397669.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2577	27	72

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G44910.1	1e-101	homeobox-leucine zipper protein 4

Link Out ? help Back to Top
Phytozome	Thhalv10001549m
Entrez Gene	18015698

Publications ? help Back to Top
Carabelli M,Turchi L,Ruzza V,Morelli G,Ruberti I Homeodomain-Leucine Zipper II family of transcription factors to the limelight: central regulators of plant development. Plant Signal Behav, 2014. [PMID:23838958] Francisco M, et al. Genome Wide Association Mapping in Arabidopsis thaliana Identifies Novel Genes Involved in Linking Allyl Glucosinolate to Altered Biomass and Defense. Front Plant Sci, 2016. 7: p. 1010 [PMID:27462337] Gallemí M, et al. A non-DNA-binding activity for the ATHB4 transcription factor in the control of vegetation proximity. New Phytol., 2017. 216(3): p. 798-813 [PMID:28805249]