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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | SMil_00018132-RA_Salv | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
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Family | MYB | ||||||||
Protein Properties | Length: 456aa MW: 51442.1 Da PI: 7.1107 | ||||||||
Description | MYB family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | Myb_DNA-binding | 42.2 | 1.8e-13 | 31 | 75 | 3 | 48 |
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +W++eEd++l + ++++G+++W Ia+++ +t qc+ rw++yl SMil_00018132-RA_Salv 31 SWSQEEDDILREQIRLHGSENWGIIASKFK-DKTTRQCRRRWFTYL 75 6****************************9.*************97 PP | |||||||
2 | Myb_DNA-binding | 44.5 | 3.7e-14 | 81 | 124 | 1 | 46 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +g W++eEd ll +a + +G++ W+ Ia+ + gRt++ +k+r+ + SMil_00018132-RA_Salv 81 KGGWSPEEDMLLCEAQRIYGNR-WTEIAKVVS-GRTDNAVKNRFTT 124 688*******************.*********.**********976 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
PROSITE profile | PS51294 | 14.313 | 24 | 75 | IPR017930 | Myb domain |
SMART | SM00717 | 5.1E-12 | 28 | 77 | IPR001005 | SANT/Myb domain |
CDD | cd00167 | 2.30E-11 | 31 | 75 | No hit | No description |
Gene3D | G3DSA:1.10.10.60 | 6.0E-20 | 32 | 82 | IPR009057 | Homeodomain-like |
Pfam | PF13921 | 7.2E-15 | 32 | 92 | No hit | No description |
SuperFamily | SSF46689 | 4.12E-25 | 54 | 133 | IPR009057 | Homeodomain-like |
PROSITE profile | PS51294 | 20.68 | 76 | 130 | IPR017930 | Myb domain |
SMART | SM00717 | 2.0E-15 | 80 | 128 | IPR001005 | SANT/Myb domain |
Gene3D | G3DSA:1.10.10.60 | 8.4E-20 | 83 | 129 | IPR009057 | Homeodomain-like |
CDD | cd00167 | 7.56E-11 | 84 | 125 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0003677 | Molecular Function | DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 456 aa Download sequence Send to blast |
MKKKEVHCSS SNLDADIGEV LLKKKERHIV SWSQEEDDIL REQIRLHGSE NWGIIASKFK 60 DKTTRQCRRR WFTYLNSDFK KGGWSPEEDM LLCEAQRIYG NRWTEIAKVV SGRTDNAVKN 120 RFTTLCKKRA KREALVEKNS TTSYVNLNNK RVVFRSGLSS NHGSENAPKK LRGENVDGVE 180 EGSTDKCDSK FARTFLEKDD PKVLALLQQA ELLSSLAIKV DAEKTGQSLE NAWMVLQDFL 240 EQSKERQQLL KMTDADADAD FRVEKLNALA EEIRSCDEGS RSSSPASSEY STGSTLVPDV 300 PRDERGECEE ETAALHQEKL DKHCLSGTST DEVKNMSTYE DIKGDNEEFS SPTNVTPLFR 360 ALAATIPSPK FSESEKHFLM KTLGLESSSQ SKVTNPSQPP PPCKRSLFAV GLQPSRPVFL 420 QIGPRRSAFL LPRMLRSTPA FEDRSSLICI LEFLLF |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1a5j_A | 3e-25 | 32 | 129 | 10 | 107 | B-MYB |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB88, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:11536724, PubMed:9684356, PubMed:16155180, PubMed:24123248). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Also involved in the shape regulation of pavement cells (PubMed:9684356). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Promotes histone H3K27me3 marks and represses stem cell gene expression (PubMed:24654956). Required for lateral roots (LRs) initiation via the regulation of PIN3 expression in an auxin-dependent manner (PubMed:26578065). Involved in responses to gravity stimulation in primary roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells, thus modulating auxin asymmetric redistribution (PubMed:26578169). {ECO:0000269|PubMed:11536724, ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169, ECO:0000269|PubMed:9684356}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Strongly induced by auxin in a IAA14/SLR1 and ARF7 dependent manner, especially in xylem pole pericycle cells, lateral roots initiating cells. {ECO:0000269|PubMed:26578065}. |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | KF059464 | 0.0 | KF059464.1 Salvia miltiorrhiza MYB-related transcription factor (MYB110) mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_020547095.1 | 1e-180 | transcription factor MYB88-like isoform X2 | ||||
Swissprot | Q94FL6 | 1e-134 | MY124_ARATH; Transcription factor MYB124 | ||||
TrEMBL | A0A059PRX9 | 0.0 | A0A059PRX9_SALMI; MYB-related transcription factor | ||||
STRING | Migut.K00887.1.p | 1e-147 | (Erythranthe guttata) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA4124 | 21 | 34 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G14350.2 | 1e-116 | MYB family protein |