PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00008695-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family ARR-B
Protein Properties Length: 605aa    MW: 67119.8 Da    PI: 6.7665
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00008695-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like91.76.2e-29214267155
                G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                            kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  SMil_00008695-RA_Salv 214 KPRVVWSVELHQQFVTAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 267
                            79*******************.********************************8 PP
2Response_reg75.22.4e-25341421109
                            EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHH CS
           Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeeda 86 
                            vl+vdD+p+ +++l+++l++  y ev+++  +e al+ l++++  +D+++ D+ mp+mdG++ll++   e  +lp+i+++a ++++ +
  SMil_00008695-RA_Salv  34 VLVVDDDPTCLRILEKMLKNCLY-EVTTCNRAEVALNFLRDNKngCDIVISDVHMPDMDGFKLLEHVGLEM-DLPVIMMSADDSKQVV 119
                            89*********************.***************888889**********************6644.8*************** PP

                            HHHHHTTESEEEESS--HHHHHH CS
           Response_reg  87 lealkaGakdflsKpfdpeelvk 109
                             + +  Ga d+l Kp+ +e+l +
  SMil_00008695-RA_Salv 120 MKGVTHGACDYLIKPVRIEALKN 142
                            *******************9986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363922.6E-17513586IPR017053Response regulator B-type, plant
SuperFamilySSF521721.71E-3431155IPR011006CheY-like superfamily
Gene3DG3DSA:3.40.50.23004.7E-4231175No hitNo description
SMARTSM004485.8E-2932144IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.01633148IPR001789Signal transduction response regulator, receiver domain
PfamPF000722.0E-2234142IPR001789Signal transduction response regulator, receiver domain
CDDcd001563.93E-2635147No hitNo description
PROSITE profilePS5129410.301211270IPR017930Myb domain
SuperFamilySSF466893.76E-20212271IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.6E-30213272IPR009057Homeodomain-like
TIGRFAMsTIGR015577.3E-25214267IPR006447Myb domain, plants
PfamPF002499.2E-8216266IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010082Biological Processregulation of root meristem growth
GO:0010119Biological Processregulation of stomatal movement
GO:0010150Biological Processleaf senescence
GO:0071368Biological Processcellular response to cytokinin stimulus
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 605 aa     Download sequence    Send to blast
MDLGVKSTPF TSSNASWKSG ADAIPGQFPA GLKVLVVDDD PTCLRILEKM LKNCLYEVTT  60
CNRAEVALNF LRDNKNGCDI VISDVHMPDM DGFKLLEHVG LEMDLPVIMM SADDSKQVVM  120
KGVTHGACDY LIKPVRIEAL KNIWQHVVRK KKHEWREKDL EHSGSVEEGE RQQKPHEDVD  180
CSSSVNEGNW KNSKKRKDEE DEAEERDDTS ALKKPRVVWS VELHQQFVTA VNQLGIDKAV  240
PKKILELMNV PGLTRENVAS HLQKYRLYLR RLSGVSQHHN GLGSSFMGPT DTQFGQMSSL  300
NGVDLQALAA SGQIPHQSLA SMQAAALGRA TSKSAVPLPL VDQRNVFNFE NPKLRFVEAQ  360
HESSKQVNLL HGIPTNMDSK QLATLHQSVL GNMNMHIHSQ TSQSSSLLMQ MAQLQPQSRT  420
QILNEINGLK TFSTEFLGND YFPTSSNSGM SSTEMKESRG FLPNYDVLNN LNQNRSQEWR  480
LRNAGSTFGP PRQSNIQGGL DASPSLSMSG QSRISSANKA ALSLAEGRSH TPNVTQHLNF  540
PASDKSLRNK AERPPGIGFQ NNLLHECFGQ EDLMSALLKQ QQEGMVVPIE AEFGFDGYQL  600
DNLPV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A1e-21210273164ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00054PBMTransfer from AT4G16110Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011100812.10.0two-component response regulator ARR2 isoform X1
SwissprotQ9ZWJ90.0ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A4D9BHL40.0A0A4D9BHL4_SALSN; Two-component response regulator ARR-B family
STRINGMigut.G00111.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA31912450
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-165response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]