PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

ERF

Protein Properties

Length: 241aa MW: 27105.3 Da PI: 4.7734

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_06009.1_g00002.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	60.6	3.7e-19	80	129	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 y+G+r ++ +g+W++eIrdp + +r++lg+f taeeAa a++ a+k+++g Rsa1.0_06009.1_g00002.1 80 VYRGIRKRP-WGKWASEIRDPE----KgARVWLGTFNTAEEAAMAYDVAAKRIRG 129 69*****.******73....24**********************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	23.538	80	137	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.4E-31	80	138	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	5.49E-22	80	138	IPR016177	DNA-binding domain
SMART	SM00380	2.8E-35	80	143	IPR001471	AP2/ERF domain
Pfam	PF00847	5.7E-13	80	129	IPR001471	AP2/ERF domain
CDD	cd00018	8.03E-32	81	138	No hit	No description
PRINTS	PR00367	1.2E-11	81	92	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.2E-11	103	119	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008219	Biological Process	cell death
GO:0009723	Biological Process	response to ethylene
GO:0009735	Biological Process	response to cytokinin
GO:0009753	Biological Process	response to jasmonic acid
GO:0010286	Biological Process	heat acclimation
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0051707	Biological Process	response to other organism
GO:0005634	Cellular Component	nucleus
GO:0005737	Cellular Component	cytoplasm
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 241 aa Download sequence Send to blast
MCGGAVISDF APSVTRAKSR KLTAEELWSE LDASACDDFW GFDSTFKLLP TKQQVTLKDE 60 AADKEKEPAA TEKRKERKNV YRGIRKRPWG KWASEIRDPE KGARVWLGTF NTAEEAAMAY 120 DVAAKRIRGD KAKLNFSDIL HNPPPAIPTL PRPDNQPPVK KLCVSSQSEL TQSSFPGECI 180 EFGNGDEFRN MSYGYDLKQQ ISSLEYFFEL DGTTPEQPSQ LHETGSEVDL WTLDDVIASY 240 E

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	6e-22	81	136	3	59	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	73	87	RKERKNVYRGIRKRP

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:9159183}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00109	PBM	Transfer from AT3G16770	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_06009.1_g00002.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Also induced by cadmium. {ECO:0000269\|PubMed:18836139, ECO:0000269\|PubMed:9159183}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC189317	0.0	AC189317.2 Brassica rapa subsp. pekinensis cultivar Inbred line 'Chiifu' clone KBrB036B21, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018486289.1	1e-179	PREDICTED: ethylene-responsive transcription factor RAP2-3-like
Swissprot	P42736	1e-119	RAP23_ARATH; Ethylene-responsive transcription factor RAP2-3
TrEMBL	A0A3N6TP03	1e-155	A0A3N6TP03_BRACR; Uncharacterized protein
STRING	Bra001640.1-P	1e-155	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G16770.1	1e-105	ethylene-responsive element binding protein

Publications ? help Back to Top
Bueso E, et al. The lithium tolerance of the Arabidopsis cat2 mutant reveals a cross-talk between oxidative stress and ethylene. Plant J., 2007. 52(6): p. 1052-65 [PMID:17931347] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chen YC, et al. Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance. Sci Rep, 2014. 4: p. 5584 [PMID:24998294] Deslauriers SD,Alvarez AA,Lacey RF,Binder BM,Larsen PB Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis. New Phytol., 2015. 208(2): p. 442-55 [PMID:25988998] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Liu W, et al. Ethylene response factor AtERF72 negatively regulates Arabidopsis thaliana response to iron deficiency. Biochem. Biophys. Res. Commun., 2017. 491(3): p. 862-868 [PMID:28390898] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474]