PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_9206_f_4
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family MIKC_MADS
Protein Properties Length: 142aa    MW: 16258.9 Da    PI: 10.5221
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_9206_f_4genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF92.61.8e-29959151
                   S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
         SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                   krien   rqvtfskRrng+lKKA+ELSvLCda+v vi+fsstgklye+ss
  Neem_9206_f_4  9 KRIENLNSRQVTFSKRRNGLLKKAKELSVLCDADVGVIVFSSTGKLYEFSS 59
                   79***********************************************96 PP
2K-box52.81.7e-18591223497
          K-box  34 eqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkk 97 
                    + R++ G++L+ L +keLqqLe++L +++ ++++kK+++lleq+++++  e+++  en++Lrk+
  Neem_9206_f_4  59 SSRRMNGKELDGLCFKELQQLENRLSEGIFSVKDKKEQVLLEQLKRSRLLEQKAVLENETLRKQ 122
                    56************************************************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004326.3E-43160IPR002100Transcription factor, MADS-box
PROSITE profilePS5006632.688161IPR002100Transcription factor, MADS-box
SuperFamilySSF554554.97E-30264IPR002100Transcription factor, MADS-box
CDDcd002651.25E-37260No hitNo description
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PRINTSPR004043.1E-30323IPR002100Transcription factor, MADS-box
PfamPF003197.0E-271057IPR002100Transcription factor, MADS-box
PROSITE profilePS512977.34612133IPR002487Transcription factor, K-box
PRINTSPR004043.1E-302338IPR002100Transcription factor, MADS-box
PRINTSPR004043.1E-303859IPR002100Transcription factor, MADS-box
PfamPF014861.2E-1159122IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 142 aa     Download sequence    Send to blast
MGRGKIEIKR IENLNSRQVT FSKRRNGLLK KAKELSVLCD ADVGVIVFSS TGKLYEFSSS  60
RRMNGKELDG LCFKELQQLE NRLSEGIFSV KDKKEQVLLE QLKRSRLLEQ KAVLENETLR  120
KQAIIRCSPP QAESAQVRVH LQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A2e-18160160MEF2C
5f28_B2e-18160160MEF2C
5f28_C2e-18160160MEF2C
5f28_D2e-18160160MEF2C
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Acts as both an activator and a repressor of transcription. Binds DNA in a sequence-specific manner in large CArG motif 5'-CC (A/T)8 GG-3'. Participates probably in the regulation of programs active during the early stages of embryo development. Prevents premature perianth senescence and abscission, fruits development and seed desiccation. Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4. Can enhance somatic embryo development in vitro. {ECO:0000269|PubMed:10318690, ECO:0000269|PubMed:10662856, ECO:0000269|PubMed:12226488, ECO:0000269|PubMed:12743119, ECO:0000269|PubMed:14615187, ECO:0000269|PubMed:15084721, ECO:0000269|PubMed:15686521, ECO:0000269|PubMed:17521410, ECO:0000269|PubMed:18305206, ECO:0000269|PubMed:19269998, ECO:0000269|PubMed:19767455, ECO:0000269|PubMed:8953767}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin (2,4-D). Feedback loop leading to direct down-regulation by itself. {ECO:0000269|PubMed:15686521}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024949072.11e-61agamous-like MADS-box protein AGL18 isoform X1
RefseqXP_024949073.11e-61agamous-like MADS-box protein AGL18 isoform X2
SwissprotQ388472e-42AGL15_ARATH; Agamous-like MADS-box protein AGL15
TrEMBLA0A067DSV88e-60A0A067DSV8_CITSI; Uncharacterized protein
TrEMBLA0A2H5QQR18e-60A0A2H5QQR1_CITUN; Uncharacterized protein
TrEMBLM5W7B76e-60M5W7B7_PRUPE; Uncharacterized protein (Fragment)
TrEMBLV4SC558e-60V4SC55_9ROSI; Uncharacterized protein
STRINGXP_006492965.15e-61(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM7828413
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G13790.19e-45AGAMOUS-like 15
Publications ? help Back to Top
  1. Zheng Q,Zheng Y,Perry SE
    Decreased GmAGL15 expression and reduced ethylene synthesis may contribute to reduced somatic embryogenesis in a poorly embryogenic cultivar of Glycine max.
    Plant Signal Behav, 2014.
    [PMID:23838957]
  2. Perry SE,Zheng Q,Zheng Y
    Transcriptome analysis indicates that GmAGAMOUS-Like 15 may enhance somatic embryogenesis by promoting a dedifferentiated state.
    Plant Signal Behav, 2016. 11(7): p. e1197463
    [PMID:27302197]
  3. Cosio C, et al.
    The class III peroxidase PRX17 is a direct target of the MADS-box transcription factor AGAMOUS-LIKE15 (AGL15) and participates in lignified tissue formation.
    New Phytol., 2017. 213(1): p. 250-263
    [PMID:27513887]
  4. Zheng Q,Zheng Y,Ji H,Burnie W,Perry SE
    Gene Regulation by the AGL15 Transcription Factor Reveals Hormone Interactions in Somatic Embryogenesis.
    Plant Physiol., 2016. 172(4): p. 2374-2387
    [PMID:27794101]
  5. Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
    HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 600-619
    [PMID:29475938]