PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Medtr2g098180.1 | ||||||||
Common Name | MTR_2g098180 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
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Family | AP2 | ||||||||
Protein Properties | Length: 526aa MW: 58685.4 Da PI: 6.5112 | ||||||||
Description | AP2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 47.2 | 5.7e-15 | 169 | 228 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + g ++ ++++lg ++ +e+Aa+a++ a++k++g Medtr2g098180.1 169 SIYRGVTRHRWTGRYEAHLWDnTCRrEGqsRKgRQVYLGGYDKEEKAARAYDLAALKYWG 228 57*******************665564477446*************************98 PP | |||||||
2 | AP2 | 51.3 | 2.9e-16 | 273 | 322 | 3 | 55 |
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GV+++++ grW A+I + +k +lg+fgt+eeAa+a++ a+ k++g Medtr2g098180.1 273 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFGTEEEAAEAYDIAAIKFRG 322 9***************988532...5************************998 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
CDD | cd00018 | 1.73E-22 | 169 | 238 | No hit | No description |
SuperFamily | SSF54171 | 2.42E-17 | 169 | 238 | IPR016177 | DNA-binding domain |
Pfam | PF00847 | 7.4E-12 | 169 | 228 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 19.216 | 170 | 236 | IPR001471 | AP2/ERF domain |
Gene3D | G3DSA:3.30.730.10 | 8.2E-16 | 170 | 237 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 9.7E-30 | 170 | 242 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 3.4E-6 | 171 | 182 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 3.51E-24 | 271 | 330 | No hit | No description |
SuperFamily | SSF54171 | 7.85E-18 | 271 | 331 | IPR016177 | DNA-binding domain |
Gene3D | G3DSA:3.30.730.10 | 1.1E-17 | 272 | 330 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 6.8E-32 | 272 | 336 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 19.164 | 272 | 330 | IPR001471 | AP2/ERF domain |
Pfam | PF00847 | 7.1E-11 | 273 | 322 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 3.4E-6 | 312 | 332 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 526 aa Download sequence Send to blast |
MGSNNWLSFP LSPTHHPSLP PHLQPNQSHH HFSLGTLVND NMLQNPFQNH DWNLMNSSHN 60 SNEVPKVADF LGVSSKSTEN ESDLAAYNEM NSSNHHSLDN YLFMPPVQNS SATSSNNYDQ 120 YEENPNNNLQ SLTLSMGSGT TKDSTCDNNI VEAAATPRRA LDTFGQRTSI YRGVTRHRWT 180 GRYEAHLWDN TCRREGQSRK GRQVYLGGYD KEEKAARAYD LAALKYWGTS TTTNFPISNY 240 EKEVEDMKHM TRLEFVAAIR RKSSGFSRGA SMYRGVTRHH QHGRWQARIG RVAGNKDLYL 300 GTFGTEEEAA EAYDIAAIKF RGLNAVTNFD MNRYDVKAIL ESITLPIGGG AAKRLKEAQA 360 LESSRKREQE MISLAGSTFQ YGISSNSSRI QLQGYPLMQF EQHAQQNLYD SSTQDTTSFD 420 HQSYIQTQLQ LQQQQSGGFY NYDGNFVQNN PSLMNMGMIE NNGGGGYIGN MNCANNNVVG 480 GHAAEEVAYV KVDYEMPSGD YGSWSGADAS NAAGVLTMWN DHLTN* |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Accumulates in the basal embryo region that gives rise to hypocotyl, root, and root stem cells. Expressed in the root meristem throughout embryo development. {ECO:0000269|PubMed:15454085, ECO:0000269|PubMed:20190735}. | |||||
Uniprot | TISSUE SPECIFICITY: Expressed in roots, seedlings, flowers, and siliques. Also detected at low levels in leaves. In roots, specifically detected in the distal root meristem, including the QC. This tissue specificity is regulated by auxin gradient and depends on PIN proteins. {ECO:0000269|PubMed:15454085, ECO:0000269|PubMed:15635403, ECO:0000269|PubMed:15988559, ECO:0000269|PubMed:16424342, ECO:0000269|PubMed:20190735}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs). {ECO:0000250, ECO:0000269|PubMed:15454085, ECO:0000269|PubMed:15635403, ECO:0000269|PubMed:16424342, ECO:0000269|PubMed:20190735}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Medtr2g098180.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: By auxin accumulation. {ECO:0000269|PubMed:15454085}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AC161406 | 0.0 | AC161406.8 Medicago truncatula chromosome 2 BAC clone mth2-83p17, complete sequence. | |||
GenBank | AC233177 | 0.0 | AC233177.2 Medicago truncatula strain A17 clone mth2-54k10, complete sequence. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_003597448.2 | 0.0 | AP2-like ethylene-responsive transcription factor PLT2 isoform X1 | ||||
Swissprot | Q5YGP7 | 0.0 | PLET2_ARATH; AP2-like ethylene-responsive transcription factor PLT2 | ||||
TrEMBL | G7IUD4 | 0.0 | G7IUD4_MEDTR; AP2-like ethylene-responsive transcription factor | ||||
STRING | AES67699 | 0.0 | (Medicago truncatula) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF4942 | 31 | 52 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G51190.1 | 1e-180 | AP2 family protein |
Link Out ? help Back to Top | |
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Phytozome | Medtr2g098180.1 |
Entrez Gene | 11434282 |