PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr2g064470.1

Common Name

MTR_2g064470

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

NAC

Protein Properties

Length: 307aa MW: 34667.3 Da PI: 8.0409

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr2g064470.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	166.5	9.4e-52	11	134	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevls 94 lppGfrFhP+deelv++yL kkv++++ l + +vd++k+ePwd+p+++ + kewyf+++rd+kyatg r+nrat+sgyWkatgkd+++l+ Medtr2g064470.1 11 LPPGFRFHPRDEELVCDYLMKKVTHSDSFL---MIDVDLNKCEPWDIPEAACVGGKEWYFYTQRDRKYATGLRTNRATASGYWKATGKDRAILR 101 79********************999444...789********7666789**********************************9 PP NAM 95 kkgelvglkktLvfykgrapkgektdWvmheyrl 128 kg+lvg++ktLvfy+grapkg+kt+Wvmhe+r+ Medtr2g064470.1 102 -KGTLVGMRKTLVFYQGRAPKGRKTEWVMHEFRI 134 .999**************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.4E-60	2	159	IPR003441	NAC domain
PROSITE profile	PS51005	56.164	11	158	IPR003441	NAC domain
Pfam	PF02365	2.3E-27	12	134	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 307 aa Download sequence Send to blast
MSNISMVEAK LPPGFRFHPR DEELVCDYLM KKVTHSDSFL MIDVDLNKCE PWDIPEAACV 60 GGKEWYFYTQ RDRKYATGLR TNRATASGYW KATGKDRAIL RKGTLVGMRK TLVFYQGRAP 120 KGRKTEWVMH EFRIEGPHGP PKISSSKEDW VLCRVFYKNR EVATKPPSMG SCYDDTGSSS 180 LPALMDSYIS FDQAQFHTDE YEQVPCFSMF SQNQTNPIYN NITTNMEPKL PLANNNNAST 240 FGGAPYSLDP LSCDRKVLKA VLSQLSKMER NPINDQNLKG SSPSLGEGSS ESYLSEVGMP 300 HMWNNF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	4e-49	6	165	12	171	NO APICAL MERISTEM PROTEIN
1ut4_B	4e-49	6	165	12	171	NO APICAL MERISTEM PROTEIN
1ut7_A	4e-49	6	165	12	171	NO APICAL MERISTEM PROTEIN
1ut7_B	4e-49	6	165	12	171	NO APICAL MERISTEM PROTEIN
3swm_A	4e-49	6	165	15	174	NAC domain-containing protein 19
3swm_B	4e-49	6	165	15	174	NAC domain-containing protein 19
3swm_C	4e-49	6	165	15	174	NAC domain-containing protein 19
3swm_D	4e-49	6	165	15	174	NAC domain-containing protein 19
3swp_A	4e-49	6	165	15	174	NAC domain-containing protein 19
3swp_B	4e-49	6	165	15	174	NAC domain-containing protein 19
3swp_C	4e-49	6	165	15	174	NAC domain-containing protein 19
3swp_D	4e-49	6	165	15	174	NAC domain-containing protein 19
4dul_A	4e-49	6	165	12	171	NAC domain-containing protein 19
4dul_B	4e-49	6	165	12	171	NAC domain-containing protein 19
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.3392	0.0	flower\| leaf\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Predominantly expressed in the root tip and in lateral root initiation sites. Also detected in expanding cotyledon, and in leaf primordia. {ECO:0000269\|PubMed:11114891}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that mediates auxin signaling to promote lateral root development. Activates the expression of two downstream auxin-responsive genes, DBP and AIR3. {ECO:0000269\|PubMed:11114891}.

Function -- GeneRIF ? help Back to Top
MicroRNA164 and MtNAC1 show an overlapping expression pattern in symbiotic nodules, and overexpression of this miRNA led to a reduction in nodule number. [PMID: 21770944]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr2g064470.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by auxin.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ343415	0.0	HQ343415.1 Medicago truncatula NAC1 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003595973.1	0.0	NAC domain-containing protein 21/22
Swissprot	Q84TE6	1e-129	NAC22_ARATH; NAC domain-containing protein 21/22
TrEMBL	F6KIF1	0.0	F6KIF1_MEDTR; NAC transcription factor-like protein
STRING	AES66224	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF10010	32	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G56010.2	1e-125	NAC domain containing protein 1

Link Out ? help Back to Top
Phytozome	Medtr2g064470.1
Entrez Gene	11423905

Publications ? help Back to Top
D'haeseleer K, et al. Transcriptional and post-transcriptional regulation of a NAC1 transcription factor in Medicago truncatula roots. New Phytol., 2011. 191(3): p. 647-61 [PMID:21770944] Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Le Hénanff G, et al. Grapevine NAC1 transcription factor as a convergent node in developmental processes, abiotic stresses, and necrotrophic/biotrophic pathogen tolerance. J. Exp. Bot., 2013. 64(16): p. 4877-93 [PMID:24043850] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Huo X,Wang C,Teng Y,Liu X Identification of miRNAs associated with dark-induced senescence in Arabidopsis. BMC Plant Biol., 2015. 15: p. 266 [PMID:26530097] Chen X, et al. Auxin-Independent NAC Pathway Acts in Response to Explant-Specific Wounding and Promotes Root Tip Emergence during de Novo Root Organogenesis in Arabidopsis. Plant Physiol., 2016. 170(4): p. 2136-45 [PMID:26850273] Liu C,Wang B,Li Z,Peng Z,Zhang J TsNAC1 Is a Key Transcription Factor in Abiotic Stress Resistance and Growth. Plant Physiol., 2018. 176(1): p. 742-756 [PMID:29122985]