PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000401086
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family bHLH
Protein Properties Length: 503aa    MW: 55925.9 Da    PI: 6.3666
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000401086genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.78.8e-13356402455
                    HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
            HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                    +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  MDP0000401086 356 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAITYITDLQ 402
                    799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.9E-4449235IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.831352401IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.31E-14355406No hitNo description
SuperFamilySSF474591.7E-18355422IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.9E-10356402IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.7E-18356421IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.6E-15358407IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS516718.711437502IPR002912ACT domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 503 aa     Download sequence    Send to blast
MGEKFWVNDE DKVVXESVLG TEACQFLISL ASENALSELI RPPGQLGVQQ GLCQLVNGSN  60
WNYAIFWQAV SSKSGGPALI WGDGHCRDTK GGGAGDVNSN RDSSSEAMQK KKEVKKWVLE  120
KLHACFGGLN GDNYARRLDG VSDMEMFHLS SMFYAFQLDS ISHCGPGESY KSGKLIWVSD  180
AGSCLHHYQS RSFLARLAGF QTVVFVPMKS GVVELGSVKS TPEEQSYVDT VRSAFGESXP  240
IQAKAFPMIF GRELSLGGPK SQSVNISFTP KIEEDFAFPP ESFELQSVGT SNGCRSEDXE  300
VKLFPQMNQM MVDGFNVQTR VSSSELLKDE SSAQIDERKP RKRGRKPANG REEPLNHVEA  360
ERQRREKLNQ RFYALRAVVP NISKMDKASL LGDAITYITD LQXKIRXMET EKQMVNNKGK  420
QLPVPEIDFQ ERLEDAVVRM NCPLDSHPVS EVFRTLREHK IVAQESNVSI TDNDKVIHTF  480
SIQTQSGDAE QLKEKLVASL SK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A3e-30350434283Transcription factor MYC2
5gnj_B3e-30350434283Transcription factor MYC2
5gnj_E3e-30350434283Transcription factor MYC2
5gnj_F3e-30350434283Transcription factor MYC2
5gnj_G3e-30350434283Transcription factor MYC2
5gnj_I3e-30350434283Transcription factor MYC2
5gnj_M3e-30350434283Transcription factor MYC2
5gnj_N3e-30350434283Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1337345RKPRKRGRK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.128690.0bud| leaf| stem
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMap-Retrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008372342.20.0transcription factor bHLH3-like
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A498JXX30.0A0A498JXX3_MALDO; Uncharacterized protein
STRINGXP_008372342.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF82633445
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-165bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]