PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000229725
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family bHLH
Protein Properties Length: 583aa    MW: 64549.5 Da    PI: 8.3211
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000229725genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH36.77.3e-12437483455
                    HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
            HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                    +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ +I +Lq
  MDP0000229725 437 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAITHITDLQ 483
                    799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.2E-43130316IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474592.62E-17432503IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.456433482IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000834.45E-14436487No hitNo description
PfamPF000102.2E-9437483IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.1E-16437502IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.3E-14439488IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 583 aa     Download sequence    Send to blast
MHAMKLVMML ILLIIFTAKF PSDHVAAAAR PPGGMMKPKT FGPKTAFLPQ ARESVPTPGP  60
NPCKPKVGGG NASCGRRREV KMGEKFWVNE EDKVMVESVL GTEACRFLIS LASENVLSDL  120
IRPPGKLGVQ QGLCQLVNGS NWNYAIFWQA VGSKSGGSAL SWGDGHCRDP KDGGAGDANS  180
SRDSSLEAVQ NKEEVKKLVV EKLHACFGGL NADNYARRLD GVSDVEMFYL TSMCYAFQLD  240
SISHCGPAES YNSRKSIWVS DAGSCLHHYQ SRSFLARLAG FQTVVFVPMK SGVVELGSVK  300
STLEEQSYVD MVRSAFWESS PIQPKAFPMI FGRELSLGGP KSQSVNVSFT PKIEEDFVFP  360
SESFELQSVG TSNGFRSEGG EVKLFPQMNQ MMVDGFNTQT RVSSSELLKD ESSTQVDEQK  420
PRKRGRKPSN GREEPLNHVE AERQRREKLN QRFYALRAVV PNISKMDKAS LLGDAITHIT  480
DLQTKIRVIE TEKQMVNNKG KQLPVPEIDF QERHGDAVVR MNFPLDSHPV SDVIRTLREH  540
KIVPQESNVS ITDNDKVIHT FSIQTQGGDA EKLREKLVAF LSK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A9e-29431499270Transcription factor MYC2
5gnj_B9e-29431499270Transcription factor MYC2
5gnj_E9e-29431499270Transcription factor MYC2
5gnj_F9e-29431499270Transcription factor MYC2
5gnj_G9e-29431499270Transcription factor MYC2
5gnj_I9e-29431499270Transcription factor MYC2
5gnj_M9e-29431499270Transcription factor MYC2
5gnj_N9e-29431499270Transcription factor MYC2
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.128690.0bud| leaf| stem
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001287804.10.0transcription factor bHLH3-like
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLD9ZIN70.0D9ZIN7_MALDO; BHLH domain class transcription factor
STRINGXP_008345141.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF82633445
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-166bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]