PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 218aa MW: 24935.3 Da PI: 7.9244

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D08G0506	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	56.5	6.9e-18	84	133	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd + ng r++lg+f+++e Aa a+++a+ + +g Gh_D08G0506 84 YRGVRKRP-WGKYAAEIRDSTRNG--VRVWLGTFDSPEAAALAYDQAAFSTRG 133 9*****.******44465..********************99887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	2.2E-29	83	142	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.12E-22	83	143	IPR016177	DNA-binding domain
SMART	SM00380	1.1E-35	83	147	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.642	83	141	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.1E-10	84	95	IPR001471	AP2/ERF domain
Pfam	PF00847	5.1E-12	84	133	IPR001471	AP2/ERF domain
CDD	cd00018	7.58E-19	84	142	No hit	No description
PRINTS	PR00367	8.1E-10	107	123	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 218 aa Download sequence Send to blast
MEEFFQYHSS SQSLFRLPSP STETLPGFWD ELLLNFNDFE EMVWDDMAAA ALDKSKNSVN 60 GVKEERVTSD IPKMEELPKE EKAYRGVRKR PWGKYAAEIR DSTRNGVRVW LGTFDSPEAA 120 ALAYDQAAFS TRGPSATLNF PVEVVRESLR SIKYRCDEGC SPVLALKKRH CLRKRSKKNK 180 MVSPQKEVIS RETRQQKNLV VLEDLGSDYL EQLLTCSS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	3e-26	80	143	11	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX589103	1e-149	JX589103.1 Gossypium hirsutum clone NBRI_GE23728 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012477474.1	1e-159	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	7e-59	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A2P5SNT5	1e-160	A0A2P5SNT5_GOSBA; Uncharacterized protein
STRING	Gorai.004G057000.1	1e-159	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM24345	3	4

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	1e-55	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]