PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D06G1651

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

WRKY

Protein Properties

Length: 551aa MW: 59686.1 Da PI: 6.6704

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D06G1651	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	97.3	9.9e-31	304	362	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 +Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+aed +++++tYeg+Hnh+ Gh_D06G1651 304 SDGCQWRKYGQKMAKGNPCPRAYYRCTMAvGCPVRKQVQRCAEDRTILITTYEGNHNHP 362 7*********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.8E-33	288	364	IPR003657	WRKY domain
SuperFamily	SSF118290	9.42E-28	296	364	IPR003657	WRKY domain
PROSITE profile	PS50811	29.677	298	364	IPR003657	WRKY domain
SMART	SM00774	1.2E-36	303	363	IPR003657	WRKY domain
Pfam	PF03106	1.8E-26	305	362	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 551 aa Download sequence Send to blast
MDKGCGLALH SLSNLFPDNT SSSSNSSTRL NQNPNMFHFP VSLPCSRDDP HDSGTGTSSD 60 ENRLPVDELD FFSAATVNVK KESFHADCAR LDVNGLNLLT ANAGSDQSTV DDGVSSDVDD 120 KRVKNEVAQL QVELKRMNAE NQKLNDMVND VSNNYSALQM HLVTLMQQHQ RHEINEVKEQ 180 EASLIVPRQF MDLRPSGIAE TDHEPSHSSS EERTPSGSPP NNVQVTSPKD CLKTKNPVSQ 240 LDQESSSFRD GKRTGREESP ESENLGRNKL QKMNPSKPID QATEATMRKA RVSVRARSEA 300 PMISDGCQWR KYGQKMAKGN PCPRAYYRCT MAVGCPVRKQ VQRCAEDRTI LITTYEGNHN 360 HPLPPAAMAM ASTTASAATM LLSGSMHSGD GMMNPNLFPR ATLPCSSMAT ISASAPFPTV 420 TLDLTHSPNA LQFQRPNTQF HVSFPGQPQN STSTSATQFP QVFGQALYNQ SKFSGLQLSQ 480 DIVSSSQLQQ PQQSTLADTV SAATAAIAND PSFTAALAAA ITSIIGGAHP NSSSNTSNNN 540 NNNGNTANSR Q

Sequence ? help Back to Top

Protein Sequence Length: 551 aa Download sequence Send to blast

MDKGCGLALH SLSNLFPDNT SSSSNSSTRL NQNPNMFHFP VSLPCSRDDP HDSGTGTSSD  60
ENRLPVDELD FFSAATVNVK KESFHADCAR LDVNGLNLLT ANAGSDQSTV DDGVSSDVDD  120
KRVKNEVAQL QVELKRMNAE NQKLNDMVND VSNNYSALQM HLVTLMQQHQ RHEINEVKEQ  180
EASLIVPRQF MDLRPSGIAE TDHEPSHSSS EERTPSGSPP NNVQVTSPKD CLKTKNPVSQ  240
LDQESSSFRD GKRTGREESP ESENLGRNKL QKMNPSKPID QATEATMRKA RVSVRARSEA  300
PMISDGCQWR KYGQKMAKGN PCPRAYYRCT MAVGCPVRKQ VQRCAEDRTI LITTYEGNHN  360
HPLPPAAMAM ASTTASAATM LLSGSMHSGD GMMNPNLFPR ATLPCSSMAT ISASAPFPTV  420
TLDLTHSPNA LQFQRPNTQF HVSFPGQPQN STSTSATQFP QVFGQALYNQ SKFSGLQLSQ  480
DIVSSSQLQQ PQQSTLADTV SAATAAIAND PSFTAALAAA ITSIIGGAHP NSSSNTSNNN  540
NNNGNTANSR Q

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	6e-22	290	366	1	76	WRKY transcription factor 1
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Ghi.3273	0.0	ovule

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Roots, leaves, shoots, flowers and siliques.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KJ825865	0.0	KJ825865.1 Gossypium hirsutum WRKY protein 20 (WRKY20) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012452689.1	0.0	PREDICTED: probable WRKY transcription factor 31
Swissprot	Q9C519	1e-158	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A0D2SV21	0.0	A0A0D2SV21_GOSRA; Uncharacterized protein
STRING	Gorai.010G182500.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1057	28	107

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	1e-126	WRKY family protein

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]