PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 227aa MW: 26030 Da PI: 4.7389

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A11G2280	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	60.4	4.3e-19	95	144	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd + ng r++lg+f+t+e Aa a+++a+++++g Gh_A11G2280 95 YRGVRKRP-WGKYAAEIRDSTRNG--VRVWLGTFDTEESAALAYDQAALAMRG 144 9*****.******44465..***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	2.6E-36	94	158	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.196	94	152	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.2E-30	94	153	IPR001471	AP2/ERF domain
CDD	cd00018	2.97E-29	95	152	No hit	No description
SuperFamily	SSF54171	1.31E-22	95	153	IPR016177	DNA-binding domain
PRINTS	PR00367	2.3E-10	95	106	IPR001471	AP2/ERF domain
Pfam	PF00847	7.1E-14	95	144	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.3E-10	118	134	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 227 aa Download sequence Send to blast
MDSSFFQYPN LHFSSESSSS HISQENFSPH SSFSYARNQA LPFNENDSQE MLLLGVLNQA 60 PEAHSFDTTS LTSFRDDDEV NSEPVEEETV KEISYRGVRK RPWGKYAAEI RDSTRNGVRV 120 WLGTFDTEES AALAYDQAAL AMRGPMAILN FPMDKVYESL QEMNYGFEEG CSPVLTMKKK 180 YSMKTRRSGK KKMMKKDEKE NRLVLENLGT DYLEELLCLS ETATPYW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	1e-26	95	152	15	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	185	191	RRSGKKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016686568.1	1e-171	PREDICTED: ethylene-responsive transcription factor 1B-like
Refseq	XP_017628489.1	1e-171	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	3e-60	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1U8JD07	1e-169	A0A1U8JD07_GOSHI; ethylene-responsive transcription factor 1B-like
STRING	Gorai.007G280900.1	1e-142	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2275	28	76

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	1e-50	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]