PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_012824
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family AP2
Protein Properties Length: 546aa    MW: 61210.6 Da    PI: 6.6592
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_012824genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP223.11.8e-07210259855
          AP2   8 wdkkrgrWvAeIrdpse..ngkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  +++++gr++A+++d s+   g++ k  + g ++++e+Aa+a++ a++k++g
  DCAR_012824 210 RHRWTGRYEAHLWDNSStkEGQTrKGRQ-GGYDSEEKAARAYDCAALKYWG 259
                  699***********55535444525555.77******************98 PP
2AP245.51.8e-14302353155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  DCAR_012824 302 SVYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFCTQEEAAEAYDIAAIKFRG 353
                  78****************988532...5************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000182.77E-15190267No hitNo description
SMARTSM003804.3E-14191273IPR001471AP2/ERF domain
PROSITE profilePS5103216.212191267IPR001471AP2/ERF domain
SuperFamilySSF541717.19E-11209268IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.101.1E-9210268IPR001471AP2/ERF domain
PfamPF008472.4E-5210259IPR001471AP2/ERF domain
CDDcd000181.77E-22302361No hitNo description
SuperFamilySSF541711.44E-16302362IPR016177DNA-binding domain
PfamPF008473.1E-9302353IPR001471AP2/ERF domain
PROSITE profilePS5103218.492303361IPR001471AP2/ERF domain
SMARTSM003804.8E-30303367IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.7E-17303361IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 546 aa     Download sequence    Send to blast
MPLNSDGSLC IMKNPSRSQH SQDSPKLENL LGNATIGAHC INYEREAMAL SFDNMYYHQN  60
VNDQEPDQSQ RQQQEEEAHL QYFSGMPCYE MYQTNDLFPG NFKGQQLGNN TMLHDHSSVE  120
PMGYGDLQCL SLSMSPGSQS SSITPATQIS PTESHCLAIE TKKRGTGSAK LSTKQPSHRK  180
TIDTFGQRTS QYRGVTRLVI NLAEFDNLLR HRWTGRYEAH LWDNSSTKEG QTRKGRQGGY  240
DSEEKAARAY DCAALKYWGS ATHINFPLES YQQQLEDMNS MNRQEYVAHL RRRSSGFSRG  300
ASVYRGVTRH HQHGRWQARI GRVAGNKDLY LGTFCTQEEA AEAYDIAAIK FRGIGAVTNF  360
EMTKYDVEKI MASDTLLAGE QARRINDIEE SRLTEAIVEY VIPASVAPGQ ENNYQNTSHD  420
NNGRSIDWKM MLNQFPHQQQ QNVEAVAENQ RHDKNLSFSV ALQNLISDET LSSSSTQLML  480
HDSSSTKTDD RHHFSDPSSL VTSLGSSREA SPDKPCFSSW ISGAQMRPAQ TSMAHLPVFG  540
SCNSP*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017244219.10.0PREDICTED: AP2-like ethylene-responsive transcription factor AIL1
SwissprotQ389141e-131ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A165ZAT00.0A0A165ZAT0_DAUCS; Uncharacterized protein
STRINGEMJ260440.0(Prunus persica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20742460
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-100AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]