PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

ERF

Protein Properties

Length: 227aa MW: 25426.7 Da PI: 5.2668

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa11g064550.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.8	7.3e-20	113	163	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIrdp +ng +r++lg+f tae+Aa a+++a+ +++g Csa11g064550.1 113 HYRGVRQRP-WGKFAAEIRDPAKNG--ARVWLGTFETAEDAALAYDRAAFRMRG 163 8******.*******9987..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	4.99E-33	112	171	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.3E-32	112	171	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.276	113	171	IPR001471	AP2/ERF domain
SMART	SM00380	6.8E-41	113	177	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.57E-23	113	173	IPR016177	DNA-binding domain
Pfam	PF00847	4.8E-14	113	163	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-11	114	125	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-11	137	153	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0001944	Biological Process	vasculature development
GO:0009864	Biological Process	induced systemic resistance, jasmonic acid mediated signaling pathway
GO:0010200	Biological Process	response to chitin
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0051301	Biological Process	cell division
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 227 aa Download sequence Send to blast
MYGQCDIESD YDLLEMVRCH LLGGENELRL NESMPSSCLT ERWGDLPLKE NDSEDMLVYG 60 LLKDAFHFDT SSSDLSCLYD FPAVKIEPTE VLAAEKPKKA VTVAAEEAPK GKHYRGVRQR 120 PWGKFAAEIR DPAKNGARVW LGTFETAEDA ALAYDRAAFR MRGSRALLNF PLRVNSGEPE 180 PVRITSKRSS SSSENGKLKR RKKTEYLTSE VKCEVGDETR VDELLV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	1e-44	110	178	2	70	ATERF1
3gcc_A	1e-44	110	178	2	70	ATERF1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Involved in disease resistance pathways. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:9756931}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00548	DAP	Transfer from AT5G47220	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa11g064550.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by jasmonate (JA) and Alternaria brassicicola (locally and systemically). Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2) while wounding induction does not require EIN2. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:12805630}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB008104	1e-146	AB008104.1 Arabidopsis thaliana AtERF-2 mRNA for ethylene responsive element binding factor 2, complete cds.
GenBank	AB018117	1e-146	AB018117.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MQL5.
GenBank	AK175151	1e-146	AK175151.1 Arabidopsis thaliana mRNA for ethylene responsive element binding factor 2 (ATERF2), complete cds, clone: RAFL21-57-E18.
GenBank	AK175229	1e-146	AK175229.1 Arabidopsis thaliana mRNA for ethylene responsive element binding factor 2, complete cds, clone: RAFL21-65-J18.
GenBank	AK176532	1e-146	AK176532.1 Arabidopsis thaliana mRNA for ethylene responsive element binding factor 2 (ATERF2), complete cds, clone: RAFL25-05-B19.
GenBank	AK176606	1e-146	AK176606.1 Arabidopsis thaliana mRNA for ethylene responsive element binding factor 2 (ATERF2), complete cds, clone: RAFL25-13-E16.
GenBank	AK176825	1e-146	AK176825.1 Arabidopsis thaliana mRNA for ethylene responsive element binding factor 2 (ATERF2), complete cds, clone: RAFL25-38-F08.
GenBank	BT024470	1e-146	BT024470.1 Arabidopsis thaliana At5g47220 mRNA, complete cds.
GenBank	CP002688	1e-146	CP002688.1 Arabidopsis thaliana chromosome 5 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010441485.1	1e-167	PREDICTED: ethylene-responsive transcription factor 2-like
Swissprot	O80338	1e-131	EF101_ARATH; Ethylene-responsive transcription factor 2
TrEMBL	A0A178UCP3	1e-129	A0A178UCP3_ARATH; ERF2
STRING	XP_010441485.1	1e-167	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G47220.1	1e-112	ethylene responsive element binding factor 2

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]