PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

MIKC_MADS

Protein Properties

Length: 208aa MW: 23896.3 Da PI: 8.6648

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa02g016200.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	97	8.1e-31	9	59	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 krien + rqvtfskRrng+lKKA+ELSvLCdaeva+iifs++gklye+ss Csa02g016200.1 9 KRIENATSRQVTFSKRRNGLLKKAFELSVLCDAEVALIIFSPRGKLYEFSS 59 79***********************************************96 PP
2	K-box	77.1	4.6e-26	80	172	7	99
K-box 7 ksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkle 99 +++ + ++++++ e L ++ie L+ + R+++Ge+L+ s++eLqqLe+qL++sl kiR+kK++ll+e+ie+l++ke++l enk+L +k e Csa02g016200.1 80 NHKRNDNSQQSKDETYGLARKIEHLEISTRKMMGEGLDASSIEELQQLENQLDRSLMKIRAKKYQLLREEIEKLKEKERNLVAENKMLMEKCE 172 4467788999*******************************************************************************9976 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	1.2E-41	1	60	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	32.071	1	61	IPR002100	Transcription factor, MADS-box
SuperFamily	SSF55455	3.66E-32	3	74	IPR002100	Transcription factor, MADS-box
PROSITE pattern	PS00350	0	3	57	IPR002100	Transcription factor, MADS-box
CDD	cd00265	6.79E-41	3	72	No hit	No description
PRINTS	PR00404	4.1E-31	3	23	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	4.8E-27	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	4.1E-31	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	4.1E-31	38	59	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	2.6E-25	84	172	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	15.653	87	177	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 208 aa Download sequence Send to blast
MVRGKTEMKR IENATSRQVT FSKRRNGLLK KAFELSVLCD AEVALIIFSP RGKLYEFSSS 60 SSIPKTVERY QKRIQDLGSN HKRNDNSQQS KDETYGLARK IEHLEISTRK MMGEGLDASS 120 IEELQQLENQ LDRSLMKIRA KKYQLLREEI EKLKEKERNL VAENKMLMEK CEMGGRGIVA 180 RTSSSTTTEE VDIDDNEMEV VTDLFIGP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5f28_A	2e-16	1	60	1	60	MEF2C
5f28_B	2e-16	1	60	1	60	MEF2C
5f28_C	2e-16	1	60	1	60	MEF2C
5f28_D	2e-16	1	60	1	60	MEF2C
6byy_A	2e-16	1	60	1	60	MEF2 CHIMERA
6byy_B	2e-16	1	60	1	60	MEF2 CHIMERA
6byy_C	2e-16	1	60	1	60	MEF2 CHIMERA
6byy_D	2e-16	1	60	1	60	MEF2 CHIMERA
6bz1_A	2e-16	1	60	1	60	MEF2 CHIMERA
6bz1_B	2e-16	1	60	1	60	MEF2 CHIMERA
6bz1_C	2e-16	1	60	1	60	MEF2 CHIMERA
6bz1_D	2e-16	1	60	1	60	MEF2 CHIMERA
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that regulates root development by controlling meristem size and patterning of the root apical meristem. Regulates auxin transport and gradients in the root meristematic cells via direct regulation of the auxin efflux carrier PIN1 and PIN4 gene expression. Binds specifically to the CArG-box DNA sequences in the promoter regions of PIN1 and PIN4 genes (PubMed:24121311). Involved in the regulation of shoot apical meristem (SAM) cell identities and transitions. Promotes flowering transition and participates in flower meristem maintenance and determinacy. Positively regulates TFL1 and WUS expression. Binds directly to the TFL1 regulatory sequences (PubMed:25636918). {ECO:0000269\|PubMed:24121311}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa02g016200.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin. {ECO:0000269\|PubMed:24121311}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK230464	0.0	AK230464.1 Arabidopsis thaliana mRNA for MADS-box protein AGL14, complete cds, clone: RAFL26-03-G06.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010434076.1	1e-150	PREDICTED: agamous-like MADS-box protein AGL14
Refseq	XP_019087272.1	1e-150	PREDICTED: agamous-like MADS-box protein AGL14
Swissprot	Q38838	1e-128	AGL14_ARATH; Agamous-like MADS-box protein AGL14
TrEMBL	R0GXA6	1e-127	R0GXA6_9BRAS; Uncharacterized protein
STRING	XP_010434076.1	1e-150	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM78	28	413

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G11880.1	1e-127	AGAMOUS-like 14

Publications ? help Back to Top
Zimmermann P,Hirsch-Hoffmann M,Hennig L,Gruissem W GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox. Plant Physiol., 2004. 136(1): p. 2621-32 [PMID:15375207] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Qu Y, et al. Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis. J. Exp. Bot., 2017. 68(17): p. 4851-4867 [PMID:28992128]