PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 220aa MW: 25003.9 Da PI: 4.5489

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_28624_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	55.6	1.3e-17	87	137	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd + + +r++lg+f++ae Aa a+++a+ ++g Cotton_A_28624_BGI-A2_v1.0 87 SYRGVRKRP-WGKFAAEIRDSTR---HgARVWLGTFDSAEAAALAYDQAAFLMRG 137 69*****.******422...25*********************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	8.87E-20	86	145	No hit	No description
Gene3D	G3DSA:3.30.730.10	9.2E-31	87	146	IPR001471	AP2/ERF domain
SMART	SM00380	1.7E-36	87	151	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.97E-22	87	146	IPR016177	DNA-binding domain
Pfam	PF00847	4.2E-13	87	137	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.906	87	145	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.6E-10	88	99	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.6E-10	111	127	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 220 aa Download sequence Send to blast
MEEESWLFQY SNNAELLAFG SEEAFSSSCE WDELLLKFNI SQETAWMDLL GDEEEERGKA 60 SSEFSDNSID GVKEEEVCSE EPKETKSYRG VRKRPWGKFA AEIRDSTRHG ARVWLGTFDS 120 AEAAALAYDQ AAFLMRGPSA TLNFPTEAVK ASLKELKCRC DEDKGWSPVV DLKNRYSSRK 180 RSKNKKIKPK DAALRQQQNL LVFEDLGADY LEQLLISSCE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	9e-28	84	147	11	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	179	185	KRSKNKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX615721	5e-75	JX615721.1 Gossypium hirsutum clone NBRI_GE59864 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017634489.1	1e-160	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	3e-54	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1U8P9H5	1e-158	A0A1U8P9H5_GOSHI; ethylene-responsive transcription factor 1B-like
STRING	Gorai.001G253000.1	1e-146	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM18989	3	8

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	1e-33	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]