PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 225aa MW: 25339.2 Da PI: 4.7079

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_03026_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.3	1.9e-18	85	135	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd + ng r++lg+f++ae Aa a+++a+ +++g Cotton_A_03026_BGI-A2_v1.0 85 SYRGVRKRP-WGKYAAEIRDSTRNG--VRVWLGTFDSAEAAAIAYDQAAFSMKG 135 69*****.******44465..**********************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	3.27E-19	84	144	No hit	No description
PROSITE profile	PS51032	22.392	85	143	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.5E-29	85	144	IPR001471	AP2/ERF domain
SMART	SM00380	3.6E-37	85	149	IPR001471	AP2/ERF domain
Pfam	PF00847	3.3E-12	85	135	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	7.85E-22	85	145	IPR016177	DNA-binding domain
PRINTS	PR00367	3.9E-10	86	97	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.9E-10	109	125	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 225 aa Download sequence Send to blast
MEEPTLFQNS TTPDFSPESS SFGCWDDLLP DYNISIPFNF SDLDEMIWMD SLGDGPKEST 60 ESSSTNSVRE EEVTSDANHP KKEKSYRGVR KRPWGKYAAE IRDSTRNGVR VWLGTFDSAE 120 AAAIAYDQAA FSMKGSLATL NFPVEVVRES LQDIKYRCEE GCSPVVALKK RHCLRKRSKS 180 TNKNTKQNVA PTPLQHQNLV VLEDLGADYL EQLLTSCETE TNVPW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	4e-28	84	146	1	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	4e-28	82	146	2	66	ATERF1
3gcc_A	4e-28	82	146	2	66	ATERF1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF430217	0.0	KF430217.1 Gossypium hirsutum transcription factor ERF10 (ERF10) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017648633.1	1e-169	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	7e-68	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	U5YF92	1e-167	U5YF92_GOSHI; Transcription factor ERF10
STRING	Gorai.007G145800.1	1e-155	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2275	28	76

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	2e-54	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]