PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA18G00181
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family ARR-B
Protein Properties Length: 233aa    MW: 26176.4 Da    PI: 8.7115
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA18G00181genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like76.43.7e-24171220151
     G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQ 51 
                 kpr++W+ eLH++Fv av+qL   ekA+Pk+ile+m+v+gLt+e+v+SHLQ
  AA18G00181 171 KPRVVWSVELHQQFVAAVNQL-SVEKAVPKKILEMMNVPGLTRENVASHLQ 220
                 79*******************.9**************************** PP

2Response_reg84.62.9e-28331411109
                   EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTES CS
  Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGak 95 
                   vl+vdD+p+ +++l+++l+  +y +v+ +  +e al ll++++  +D+++ D+ mp+mdG++ll++i  e  +lp+i+++a ++++ +l+ +  Ga 
    AA18G00181  33 VLVVDDDPTSLMILEKMLRTCRY-RVTKCNRAEIALSLLRKNKngFDIVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDSKSVVLKGVTHGAV 127
                   89*********************.***************999999**********************6654.8************************ PP

                   EEEESS--HHHHHH CS
  Response_reg  96 dflsKpfdpeelvk 109
                   d+l Kp+ +e+l +
    AA18G00181 128 DYLIKPVRIEALKN 141
                   **********9986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.40.50.23001.0E-4230169No hitNo description
SuperFamilySSF521724.84E-3730162IPR011006CheY-like superfamily
SMARTSM004482.2E-3031143IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.35432147IPR001789Signal transduction response regulator, receiver domain
PfamPF000721.0E-2433141IPR001789Signal transduction response regulator, receiver domain
CDDcd001561.39E-2734146No hitNo description
SuperFamilySSF466891.04E-15168221IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.0E-23170220IPR009057Homeodomain-like
TIGRFAMsTIGR015571.8E-20171221IPR006447Myb domain, plants
PfamPF002493.1E-6173221IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 233 aa     Download sequence    Send to blast
MMNPGLVRVP ESNSGRNLAG EVAPDQFPAG LRVLVVDDDP TSLMILEKML RTCRYRVTKC  60
NRAEIALSLL RKNKNGFDIV ISDVHMPDMD GFKLLEHIGL EMDLPVIMMS ADDSKSVVLK  120
GVTHGAVDYL IKPVRIEALK NIWQHVVRKK RNEWNVSEQR DDKEDASTLT KPRVVWSVEL  180
HQQFVAAVNQ LSVEKAVPKK ILEMMNVPGL TRENVASHLQ SVDDSKSVSK SKL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A3e-18171220554ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA18G00181
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013671742.11e-126two-component response regulator ARR2
SwissprotQ9ZWJ91e-123ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A0D3A7S01e-124A0A0D3A7S0_BRAOL; Two-component response regulator
STRINGBo1g055180.11e-125(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM24032773
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-125response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]