PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA18G00127
Organism
Aethionema arabicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family HD-ZIP
Protein Properties Length: 819aa    MW: 89797 Da    PI: 6.1081
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA18G00127genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox56.45e-182178457
                -SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
    Homeobox  4 RttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                  ++++eq+e+Le+++ ++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  AA18G00127 21 YVRYSPEQVEALERVYTECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 78
                6789****************************************************97 PP
2START181.83.7e-571413492205
                 HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEXX CS
       START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvael 98 
                 +aeea++e+++ka+ ++  Wv++  +++g++++ +++ s+++sg a+ra+g+v  +++  v+e+l+d++ W ++++ ++tl vi  g  g+++l+++++
  AA18G00127 141 IAEEALAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAVSRNCSGIAARACGLVSLEPM-KVAEILKDRPSWFRDCRCVDTLSVIPAGngGTIELIYTQM 238
                 799*******************************************************.8888888888*****************999********** PP

                 TTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHH CS
       START  99 qalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaega 193
                 +a+++l++ Rdf+++Ry+ +l++g++v++++S++s +  p+   sss+vRae + Sg+li+p+++g+s v++v+hvdl++++++++lr+l++s+ + ++
  AA18G00127 239 YAPTTLAAaRDFWTLRYSTSLEDGSYVVCERSLTSATGGPTgpsSSSFVRAEIRSSGFLIRPCDGGGSIVHIVDHVDLDAWSVPEVLRPLYESSKILAQ 337
                 **************************************999999******************************************************* PP

                 HHHHHHTXXXXX CS
       START 194 ktwvatlqrqce 205
                 k++va+l++ ++
  AA18G00127 338 KMTVAALRHVRQ 349
                 *******98765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.2241579IPR001356Homeobox domain
SMARTSM003899.3E-151783IPR001356Homeobox domain
SuperFamilySSF466891.11E-161983IPR009057Homeodomain-like
CDDcd000866.42E-162080No hitNo description
PfamPF000461.5E-152178IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.603.8E-182278IPR009057Homeodomain-like
CDDcd146865.22E-672111No hitNo description
PROSITE profilePS5084826.049131359IPR002913START domain
CDDcd088755.28E-73138351No hitNo description
Gene3DG3DSA:3.30.530.203.8E-21139345IPR023393START-like domain
SuperFamilySSF559612.47E-36140352No hitNo description
SMARTSM002341.8E-58140350IPR002913START domain
PfamPF018522.3E-54141349IPR002913START domain
SuperFamilySSF559614.67E-6388469No hitNo description
SuperFamilySSF559614.67E-6501575No hitNo description
PfamPF086702.4E-48673818IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0080060Biological Processintegument development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 819 aa     Download sequence    Send to blast
MMMTHSMNRD SPDKGLDSGK YVRYSPEQVE ALERVYTECP KPSSLRRQQL IRECPILSNI  60
EPKQIKVWFQ NRRCREKQRK EAARLQTVNR KLNAMNKLLM EENDRLQKQV SHLVYENGHM  120
KHQLHTASGT TTDNSCDLLS IAEEALAEFL SKATGTAVDW VQMIGMKPGP DSIGIVAVSR  180
NCSGIAARAC GLVSLEPMKV AEILKDRPSW FRDCRCVDTL SVIPAGNGGT IELIYTQMYA  240
PTTLAAARDF WTLRYSTSLE DGSYVVCERS LTSATGGPTG PSSSSFVRAE IRSSGFLIRP  300
CDGGGSIVHI VDHVDLDAWS VPEVLRPLYE SSKILAQKMT VAALRHVRQI AQETSGEVQY  360
GGGRQPAVLR TFSQRLCRGF NDAVNGFVDD GWTPMGSDGA EDITVMINLS PGKFGGSQYS  420
NSFLPSFGSG VLCAKASMLL QNVPPAVLVR FLREHRSEWA DYGVDAYAAA SLRSSPFAVP  480
CARAGGFPSN QVILPLAQTV EHEEFLEVIR LEGHAYSPED MGLARDMYLL QLCSGVDENV  540
VGGCAQLVFA PIDESFADDA PLLPSGFRVI PLEHNTNLNG ASANRTLDLA SALEGSTRQA  600
GETDPNDCNF RSVLTIAFQF TFDNHSRDNV ASMARQYVRS IVGSIQRVAL AIAPRPGSQL  660
GSIPVPTSPE ALTLVRWITR SYSVHTGANL FGSDSQINGD TLLKQLWNYT DAILCCSLKT  720
NASPVFTFAN QAGLDMLETT LVALQDIMLD KTLDESGRKA LCSEFPKIMQ QGYAHLRAGV  780
CGSSMGRAVS YEQVVVWKVL DDDESNHCLA FMFNNWSFV
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates. {ECO:0000269|PubMed:11395776, ECO:0000269|PubMed:15328016, ECO:0000269|PubMed:15598805}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA18G00127
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR165 and miR166. {ECO:0000269|PubMed:14999284, ECO:0000269|PubMed:16033795, ECO:0000269|PubMed:17237362}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010504942.10.0PREDICTED: homeobox-leucine zipper protein ATHB-14
SwissprotO042910.0ATB14_ARATH; Homeobox-leucine zipper protein ATHB-14
TrEMBLV4M7290.0V4M729_EUTSA; Uncharacterized protein
STRINGXP_010504942.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM42562653
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G34710.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  3. Müller CJ, et al.
    PHABULOSA Mediates an Auxin Signaling Loop to Regulate Vascular Patterning in Arabidopsis.
    Plant Physiol., 2016. 170(2): p. 956-70
    [PMID:26637548]
  4. Yamada T,Sasaki Y,Hashimoto K,Nakajima K,Gasser CS
    CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules.
    Development, 2016. 143(3): p. 422-6
    [PMID:26700684]
  5. Kim ES, et al.
    HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots.
    Physiol Plant, 2016. 157(2): p. 221-33
    [PMID:26968317]
  6. Husbands AY,Aggarwal V,Ha T,Timmermans MC
    In Planta Single-Molecule Pull-Down Reveals Tetrameric Stoichiometry of HD-ZIPIII:LITTLE ZIPPER Complexes.
    Plant Cell, 2016. 28(8): p. 1783-94
    [PMID:27385814]
  7. Di Ruocco G, et al.
    Differential spatial distribution of miR165/6 determines variability in plant root anatomy.
    Development, 2018.
    [PMID:29158439]
  8. Wójcik AM,Nodine MD,Gaj MD
    miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 2024
    [PMID:29321785]
  9. Hashimoto K,Miyashima S,Sato-Nara K,Yamada T,Nakajima K
    Functionally Diversified Members of the MIR165/6 Gene Family Regulate Ovule Morphogenesis in Arabidopsis thaliana.
    Plant Cell Physiol., 2018. 59(5): p. 1017-1026
    [PMID:29462472]