PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G34710.1

Common Name

ATHB14, ATHB-14, PHB, PHB-1D, T29F13.8

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

HD-ZIP

Protein Properties

Length: 852aa MW: 93217.8 Da PI: 6.1505

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G34710.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	57.4	2.4e-18	25	83	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 k ++t+eq+e+Le+++ ++++ps +r++L +++ +++ +q+kvWFqNrR +ek+ AT2G34710.1 25 KYVRYTPEQVEALERVYTECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 83 5678*****************************************************97 PP
2	START	191.4	4.4e-60	174	382	2	205
HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEX CS START 2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvae 97 +aeea++e+++ka+ ++ Wv++ +++g++++ +++ s+++sg a+ra+g+v +++ v+e+l+d++ W +++++++tl vi g g+++l++++ AT2G34710.1 174 IAEEALAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAISRNCSGIAARACGLVSLEPM-KVAEILKDRPSWLRDCRSVDTLSVIPAGngGTIELIYTQ 270 799*****************************************************.8888888888*************999***** PP XTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHH CS START 98 lqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglae 191 ++a+++l++ Rdf+++Ry+ +l++g++v++++S++s + p+ ss++vRae+ pSg+li+p+++g+s +++v+hvdl+++++++++r+l++s+ + AT2G34710.1 271 MYAPTTLAAaRDFWTLRYSTCLEDGSYVVCERSLTSATGGPTgppSSNFVRAEMKPSGFLIRPCDGGGSILHIVDHVDLDAWSVPEVMRPLYESSKIL 368 **********************************9999999************************************************* PP HHHHHHHHTXXXXX CS START 192 gaktwvatlqrqce 205 ++k++va+l++ ++ AT2G34710.1 369 AQKMTVAALRHVRQ 382 *******98765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.321	20	84	IPR001356	Homeobox domain
SMART	SM00389	5.7E-15	22	88	IPR001356	Homeobox domain
SuperFamily	SSF46689	8.55E-17	24	88	IPR009057	Homeodomain-like
CDD	cd00086	4.10E-16	25	85	No hit	No description
Pfam	PF00046	6.4E-16	26	83	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	2.0E-18	27	83	IPR009057	Homeodomain-like
CDD	cd14686	5.48E-6	77	116	No hit	No description
PROSITE profile	PS50848	26.711	164	392	IPR002913	START domain
CDD	cd08875	1.49E-74	168	384	No hit	No description
Gene3D	G3DSA:3.30.530.20	1.2E-23	172	378	IPR023393	START-like domain
SuperFamily	SSF55961	3.16E-37	173	385	No hit	No description
SMART	SM00234	3.3E-64	173	383	IPR002913	START domain
Pfam	PF01852	1.2E-57	174	382	IPR002913	START domain
SuperFamily	SSF55961	5.49E-6	421	502	No hit	No description
SuperFamily	SSF55961	5.49E-6	534	609	No hit	No description
Pfam	PF08670	2.7E-49	706	851	IPR013978	MEKHLA

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009855	Biological Process	determination of bilateral symmetry
GO:0009944	Biological Process	polarity specification of adaxial/abaxial axis
GO:0010072	Biological Process	primary shoot apical meristem specification
GO:0030154	Biological Process	cell differentiation
GO:0080060	Biological Process	integument development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0008289	Molecular Function	lipid binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000026	anatomy	primary root tip
PO:0000037	anatomy	shoot apex
PO:0000229	anatomy	flower meristem
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0005059	anatomy	root endodermis
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009015	anatomy	portion of vascular tissue
PO:0009025	anatomy	vascular leaf
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020022	anatomy	inner integument
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020124	anatomy	root stele
PO:0020137	anatomy	leaf apex
PO:0020148	anatomy	shoot apical meristem
PO:0020149	anatomy	quiescent center
PO:0025022	anatomy	collective leaf structure
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 852 aa Download sequence Send to blast
MMMVHSMSRD MMNRESPDKG LDSGKYVRYT PEQVEALERV YTECPKPSSL RRQQLIRECP 60 ILSNIEPKQI KVWFQNRRCR EKQRKEAARL QTVNRKLNAM NKLLMEENDR LQKQVSNLVY 120 ENGHMKHQLH TASGTTTDNS CESVVVSGQQ HQQQNPNPQH QQRDANNPAG LLSIAEEALA 180 EFLSKATGTA VDWVQMIGMK PGPDSIGIVA ISRNCSGIAA RACGLVSLEP MKVAEILKDR 240 PSWLRDCRSV DTLSVIPAGN GGTIELIYTQ MYAPTTLAAA RDFWTLRYST CLEDGSYVVC 300 ERSLTSATGG PTGPPSSNFV RAEMKPSGFL IRPCDGGGSI LHIVDHVDLD AWSVPEVMRP 360 LYESSKILAQ KMTVAALRHV RQIAQETSGE VQYGGGRQPA VLRTFSQRLC RGFNDAVNGF 420 VDDGWSPMGS DGAEDVTVMI NLSPGKFGGS QYGNSFLPSF GSGVLCAKAS MLLQNVPPAV 480 LVRFLREHRS EWADYGVDAY AAASLRASPF AVPCARAGGF PSNQVILPLA QTVEHEESLE 540 VVRLEGHAYS PEDMGLARDM YLLQLCSGVD ENVVGGCAQL VFAPIDESFA DDAPLLPSGF 600 RIIPLEQKST PNGASANRTL DLASALEGST RQAGEADPNG CNFRSVLTIA FQFTFDNHSR 660 DSVASMARQY VRSIVGSIQR VALAIAPRPG SNISPISVPT SPEALTLVRW ISRSYSLHTG 720 ADLFGSDSQT SGDTLLHQLW NHSDAILCCS LKTNASPVFT FANQTGLDML ETTLVALQDI 780 MLDKTLDEPG RKALCSEFPK IMQQGYAHLP AGVCASSMGR MVSYEQATVW KVLEDDESNH 840 CLAFMFVNWS FV

Sequence ? help Back to Top

Protein Sequence Length: 852 aa Download sequence Send to blast

MMMVHSMSRD MMNRESPDKG LDSGKYVRYT PEQVEALERV YTECPKPSSL RRQQLIRECP  60
ILSNIEPKQI KVWFQNRRCR EKQRKEAARL QTVNRKLNAM NKLLMEENDR LQKQVSNLVY  120
ENGHMKHQLH TASGTTTDNS CESVVVSGQQ HQQQNPNPQH QQRDANNPAG LLSIAEEALA  180
EFLSKATGTA VDWVQMIGMK PGPDSIGIVA ISRNCSGIAA RACGLVSLEP MKVAEILKDR  240
PSWLRDCRSV DTLSVIPAGN GGTIELIYTQ MYAPTTLAAA RDFWTLRYST CLEDGSYVVC  300
ERSLTSATGG PTGPPSSNFV RAEMKPSGFL IRPCDGGGSI LHIVDHVDLD AWSVPEVMRP  360
LYESSKILAQ KMTVAALRHV RQIAQETSGE VQYGGGRQPA VLRTFSQRLC RGFNDAVNGF  420
VDDGWSPMGS DGAEDVTVMI NLSPGKFGGS QYGNSFLPSF GSGVLCAKAS MLLQNVPPAV  480
LVRFLREHRS EWADYGVDAY AAASLRASPF AVPCARAGGF PSNQVILPLA QTVEHEESLE  540
VVRLEGHAYS PEDMGLARDM YLLQLCSGVD ENVVGGCAQL VFAPIDESFA DDAPLLPSGF  600
RIIPLEQKST PNGASANRTL DLASALEGST RQAGEADPNG CNFRSVLTIA FQFTFDNHSR  660
DSVASMARQY VRSIVGSIQR VALAIAPRPG SNISPISVPT SPEALTLVRW ISRSYSLHTG  720
ADLFGSDSQT SGDTLLHQLW NHSDAILCCS LKTNASPVFT FANQTGLDML ETTLVALQDI  780
MLDKTLDEPG RKALCSEFPK IMQQGYAHLP AGVCASSMGR MVSYEQATVW KVLEDDESNH  840
CLAFMFVNWS FV

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.37771	0.0	root

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	145360618	0.0
Genevisible	267316_at	0.0
Expression Atlas	AT2G34710	-
AtGenExpress	AT2G34710	-
ATTED-II	AT2G34710	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed at the youngest stages of ovule development, predominantly to the adaxial side of the ovule primordium. Later, expression becomes restricted to a region in the distal chalaza. When the integuments initiate, expressed in the inner integument, with highest expression in the inner layer of the inner integument. Expressed in the vegetative shoot apical meristem (SAM) and initially throughout the presumptive cotyledons. At the globular stage, just before cotyledon outgrowth, expressed at high levels in cotyledon adaxial domains. Expression is lost from the SAM of torpedo stage embryos but is regained late in embryogenesis, extending to young primordia after germination, and becoming progressively restricted to the adaxial domain and the vasculature. Preferentially expressed in the adaxial domain of the developing leaf. Expressed throughout the plastochron 0 (P0) leaf primordium and expression increases in P1 to become preferentially localized to the adaxial leaf domain by the P2 stage (polar expression). {ECO:0000269\|PubMed:11395776, ECO:0000269\|PubMed:15328016}.
Uniprot	TISSUE SPECIFICITY: Expressed in the center of the meristem and on the adaxial side of the leaves. {ECO:0000269\|PubMed:11395776}.

Functional Description ? help Back to Top
Source	Description
TAIR	Dominant PHB mutations cause transformation of abaxial leaf fates into adaxial leaf fates. Encodes a member of HD-Zip family which contains homeodomain-leucine zipper domains and domain similar to a mammalian sterol binding domain. Has overlapping functions with PHAVOLUTA, REVOLUTA and CORONA.
UniProt	Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates. {ECO:0000269\|PubMed:11395776, ECO:0000269\|PubMed:15328016, ECO:0000269\|PubMed:15598805}.

Function -- GeneRIF ? help Back to Top
Pairing to the 5' portion of the small silencing RNA of PHAVOLUTA appears crucial regardless of the mode of post-transcriptional repression [PMID: 15282547] Class III HD-Zip genes required for root development [PHABULOSA (PHB)] [PMID: 15286295] findings show that the HD-ZIPIII transcription factor PHABULOSA directly activates the cytokinin biosynthesis gene ISOPENTENYL TRANSFERASE 7, thus promoting cell differentiation and regulating root length [PMID: 22902752] our study suggests that PHB can dynamically regulate TA cell activities in a QC-independent manner, and that the SHR-PHB pathway enables a robust root growth system by coordinating the stem cell niche and TA domain. [PMID: 25730098] stem cell specification pathway is normally repressed by the activity of the HD-zip III transcription factors PHABULOSA (PHB), PHAVOLUTA (PHV) and CORONA (CNA). [PMID: 26011610] PHABULOSA, directly binds the promoter of both MONOPTEROS (MP)/AUXIN RESPONSE FACTOR5, a key factor in vascular formation. [PMID: 26637548] The branching ovules of the mutant resemble those of some fossil gymnosperms, implicating BEL1 and HD-ZIPIII genes as players in the evolution of the unbranched ovule form in extant angiosperms. [PMID: 26700684] In Planta Single-Molecule Pull-Down Reveals Tetrameric Stoichiometry of HD-ZIPIII:LITTLE ZIPPER Complexes. [PMID: 27385814]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G34710.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by miR165 and miR166. {ECO:0000269\|PubMed:14999284, ECO:0000269\|PubMed:16033795, ECO:0000269\|PubMed:17237362}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source	Upstream Regulator (A: Activate/R: Repress)
ATRM	AT1G65620 (A), AT2G37630 (A), AT2G45190 (A), AT3G44750 (A), AT4G37750 (A)

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT1G65620(A), AT2G17950(R), AT2G45190(A), AT3G52770(A), AT5G16560(R)

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT2G38300
IntAct	Search O04291

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G34710

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ441291	0.0	AJ441291.1 Arabidopsis thaliana mRNA for homeodomain-leucine zipper protein 14 (ATHB-14 gene).
GenBank	AY099791	0.0	AY099791.1 Arabidopsis thaliana homeodomain transcription factor (At2g34710) mRNA, complete cds.
GenBank	BT000335	0.0	BT000335.1 Arabidopsis thaliana homeodomain transcription factor (At2g34710) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_181018.1	0.0	Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein
Swissprot	O04291	0.0	ATB14_ARATH; Homeobox-leucine zipper protein ATHB-14
TrEMBL	A0A178VWD3	0.0	A0A178VWD3_ARATH; PHB-1D
STRING	AT2G34710.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4256	26	53
Representative plant	OGRP651	16	71

Link Out ? help Back to Top
Phytozome	AT2G34710.1
Entrez Gene	818036
iHOP	AT2G34710
wikigenes	AT2G34710

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] McConnell JR, et al. Role of PHABULOSA and PHAVOLUTA in determining radial patterning in shoots. Nature, 2001. 411(6838): p. 709-13 [PMID:11395776] Eshed Y,Baum SF,Perea JV,Bowman JL Establishment of polarity in lateral organs of plants. Curr. Biol., 2001. 11(16): p. 1251-60 [PMID:11525739] Golz JF,Hudson A Signalling in plant lateral organ development. Plant Cell, 2002. 14 Suppl: p. S277-88 [PMID:12045283] Lin WC,Shuai B,Springer PS The Arabidopsis LATERAL ORGAN BOUNDARIES-domain gene ASYMMETRIC LEAVES2 functions in the repression of KNOX gene expression and in adaxial-abaxial patterning. Plant Cell, 2003. 15(10): p. 2241-52 [PMID:14508003] Emery JF, et al. Radial patterning of Arabidopsis shoots by class III HD-ZIP and KANADI genes. Curr. Biol., 2003. 13(20): p. 1768-74 [PMID:14561401] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Kidner CA,Martienssen RA Spatially restricted microRNA directs leaf polarity through ARGONAUTE1. Nature, 2004. 428(6978): p. 81-4 [PMID:14999284] Juarez MT,Kui JS,Thomas J,Heller BA,Timmermans MC microRNA-mediated repression of rolled leaf1 specifies maize leaf polarity. Nature, 2004. 428(6978): p. 84-8 [PMID:14999285] Eshed Y,Izhaki A,Baum SF,Floyd SK,Bowman JL Asymmetric leaf development and blade expansion in Arabidopsis are mediated by KANADI and YABBY activities. Development, 2004. 131(12): p. 2997-3006 [PMID:15169760] Engstrom EM,Izhaki A,Bowman JL Promoter bashing, microRNAs, and Knox genes. New insights, regulators, and targets-of-regulation in the establishment of lateral organ polarity in Arabidopsis. Plant Physiol., 2004. 135(2): p. 685-94 [PMID:15208415] Mallory AC, et al. MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region. EMBO J., 2004. 23(16): p. 3356-64 [PMID:15282547] Hawker NP,Bowman JL Roles for Class III HD-Zip and KANADI genes in Arabidopsis root development. Plant Physiol., 2004. 135(4): p. 2261-70 [PMID:15286295] Sieber P, et al. Pattern formation during early ovule development in Arabidopsis thaliana. Dev. Biol., 2004. 273(2): p. 321-34 [PMID:15328016] Prigge MJ, et al. Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development. Plant Cell, 2005. 17(1): p. 61-76 [PMID:15598805] Li H, et al. The Putative RNA-dependent RNA polymerase RDR6 acts synergistically with ASYMMETRIC LEAVES1 and 2 to repress BREVIPEDICELLUS and MicroRNA165/166 in Arabidopsis leaf development. Plant Cell, 2005. 17(8): p. 2157-71 [PMID:16006579] Williams L,Grigg SP,Xie M,Christensen S,Fletcher JC Regulation of Arabidopsis shoot apical meristem and lateral organ formation by microRNA miR166g and its AtHD-ZIP target genes. Development, 2005. 132(16): p. 3657-68 [PMID:16033795] Grigg SP,Canales C,Hay A,Tsiantis M SERRATE coordinates shoot meristem function and leaf axial patterning in Arabidopsis. Nature, 2005. 437(7061): p. 1022-6 [PMID:16222298] Lee JY, et al. Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots. Proc. Natl. Acad. Sci. U.S.A., 2006. 103(15): p. 6055-60 [PMID:16581911] Ochando I, et al. Mutations in the microRNA complementarity site of the INCURVATA4 gene perturb meristem function and adaxialize lateral organs in arabidopsis. Plant Physiol., 2006. 141(2): p. 607-19 [PMID:16617092] Franks RG,Liu Z,Fischer RL SEUSS and LEUNIG regulate cell proliferation, vascular development and organ polarity in Arabidopsis petals. Planta, 2006. 224(4): p. 801-11 [PMID:16625397] Nole-Wilson S,Krizek BA AINTEGUMENTA contributes to organ polarity and regulates growth of lateral organs in combination with YABBY genes. Plant Physiol., 2006. 141(3): p. 977-87 [PMID:16714408] Prigge MJ,Clark SE Evolution of the class III HD-Zip gene family in land plants. Evol. Dev., 2006 Jul-Aug. 8(4): p. 350-61 [PMID:16805899] Lobbes D,Rallapalli G,Schmidt DD,Martin C,Clarke J SERRATE: a new player on the plant microRNA scene. EMBO Rep., 2006. 7(10): p. 1052-8 [PMID:16977334] Huang W, et al. The proteolytic function of the Arabidopsis 26S proteasome is required for specifying leaf adaxial identity. Plant Cell, 2006. 18(10): p. 2479-92 [PMID:17028202] Zhou GK,Kubo M,Zhong R,Demura T,Ye ZH Overexpression of miR165 affects apical meristem formation, organ polarity establishment and vascular development in Arabidopsis. Plant Cell Physiol., 2007. 48(3): p. 391-404 [PMID:17237362] Ueno Y, et al. Histone deacetylases and ASYMMETRIC LEAVES2 are involved in the establishment of polarity in leaves of Arabidopsis. Plant Cell, 2007. 19(2): p. 445-57 [PMID:17293570] Chandler JW,Cole M,Flier A,Grewe B,Werr W The AP2 transcription factors DORNROSCHEN and DORNROSCHEN-LIKE redundantly control Arabidopsis embryo patterning via interaction with PHAVOLUTA. Development, 2007. 134(9): p. 1653-62 [PMID:17376809] Kim YK, et al. ATHB23, an Arabidopsis class I homeodomain-leucine zipper gene, is expressed in the adaxial region of young leaves. Plant Cell Rep., 2007. 26(8): p. 1179-85 [PMID:17387478] Fu Y, et al. Genetic interactions between leaf polarity-controlling genes and ASYMMETRIC LEAVES1 and 2 in Arabidopsis leaf patterning. Plant Cell Physiol., 2007. 48(5): p. 724-35 [PMID:17395603] Ha CM,Jun JH,Nam HG,Fletcher JC BLADE-ON-PETIOLE 1 and 2 control Arabidopsis lateral organ fate through regulation of LOB domain and adaxial-abaxial polarity genes. Plant Cell, 2007. 19(6): p. 1809-25 [PMID:17601823] Baucher M,El Jaziri M,Vandeputte O From primary to secondary growth: origin and development of the vascular system. J. Exp. Bot., 2007. 58(13): p. 3485-501 [PMID:17898423] Wenkel S,Emery J,Hou BH,Evans MM,Barton MK A feedback regulatory module formed by LITTLE ZIPPER and HD-ZIPIII genes. Plant Cell, 2007. 19(11): p. 3379-90 [PMID:18055602] Azhakanandam S,Nole-Wilson S,Bao F,Franks RG SEUSS and AINTEGUMENTA mediate patterning and ovule initiation during gynoecium medial domain development. Plant Physiol., 2008. 146(3): p. 1165-81 [PMID:18184731] Kim YS, et al. HD-ZIP III activity is modulated by competitive inhibitors via a feedback loop in Arabidopsis shoot apical meristem development. Plant Cell, 2008. 20(4): p. 920-33 [PMID:18408069] Yang JY, et al. betaC1, the pathogenicity factor of TYLCCNV, interacts with AS1 to alter leaf development and suppress selective jasmonic acid responses. Genes Dev., 2008. 22(18): p. 2564-77 [PMID:18794352] Ochando I,González-Reig S,Ripoll JJ,Vera A,Martínez-Laborda A Alteration of the shoot radial pattern in Arabidopsis thaliana by a gain-of-function allele of the class III HD-Zip gene INCURVATA4. Int. J. Dev. Biol., 2008. 52(7): p. 953-61 [PMID:18956325] Kelley DR,Skinner DJ,Gasser CS Roles of polarity determinants in ovule development. Plant J., 2009. 57(6): p. 1054-64 [PMID:19054366] Grigg SP, et al. Repression of apical homeobox genes is required for embryonic root development in Arabidopsis. Curr. Biol., 2009. 19(17): p. 1485-90 [PMID:19646874] Zhong R,Ye ZH Regulation of HD-ZIP III Genes by MicroRNA 165. Plant Signal Behav, 2007. 2(5): p. 351-3 [PMID:19704656] Yao X, et al. Two types of cis-acting elements control the abaxial epidermis-specific transcription of the MIR165a and MIR166a genes. FEBS Lett., 2009. 583(22): p. 3711-7 [PMID:19879265] Bao F,Azhakanandam S,Franks RG SEUSS and SEUSS-LIKE transcriptional adaptors regulate floral and embryonic development in Arabidopsis. Plant Physiol., 2010. 152(2): p. 821-36 [PMID:20007451] Miyashima S,Koi S,Hashimoto T,Nakajima K Non-cell-autonomous microRNA165 acts in a dose-dependent manner to regulate multiple differentiation status in the Arabidopsis root. Development, 2011. 138(11): p. 2303-13 [PMID:21558378] Arabidopsis Interactome Mapping Consortium Evidence for network evolution in an Arabidopsis interactome map. 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