PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GRMZM2G380515_P02
Common Namepco068737, ZEAMMB73_981121
Organism
Zea mays
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Family C2H2
Protein Properties Length: 476aa    MW: 53947.6 Da    PI: 8.7444
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GRMZM2G380515_P02genomeMaizeSequenceView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H215.64.6e-05172194123
                        EEETTTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                        ++C+ Cg++F  + +Lk+H+++H
  GRMZM2G380515_P02 172 HRCQECGRCFQKPAHLKQHMQSH 194
                        79*******************98 PP
2zf-C2H223.41.5e-07200224123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        + Cp  dC+ s++rk++L+rH+ +H
  GRMZM2G380515_P02 200 FICPleDCPFSYKRKDHLNRHMLKH 224
                        78*********************99 PP
3zf-C2H214.40.00011229254123
                        EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                        ++C+   C+++Fs k +++rH +  H
  GRMZM2G380515_P02 229 FSCTldGCDMRFSMKADMQRHVKEiH 254
                        899999****************9988 PP
4zf-C2H217.98.3e-06262286123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        ++C+   C+k+F+ +s Lk+H  +H
  GRMZM2G380515_P02 262 FVCKedGCNKVFRYSSKLKKHEESH 286
                        89*******************9988 PP
5zf-C2H211.70.00079353377223
                        EET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                        kC+   C   Fs+ksnL++H +  H
  GRMZM2G380515_P02 353 KCTfdGCEHFFSNKSNLTKHVKAcH 377
                        799999***************9955 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM0035522126148IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.604.2E-6170193IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.484172199IPR007087Zinc finger, C2H2
SMARTSM003550.012172194IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280174196IPR007087Zinc finger, C2H2
SuperFamilySSF576673.29E-10184226No hitNo description
Gene3DG3DSA:3.30.160.608.5E-11194226IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PfamPF000962.9E-5200224IPR007087Zinc finger, C2H2
SMARTSM003551.9E-4200224IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.037200229IPR007087Zinc finger, C2H2
PROSITE patternPS000280202224IPR007087Zinc finger, C2H2
SuperFamilySSF576677.54E-8210261No hitNo description
Gene3DG3DSA:3.30.160.602.0E-6227256IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003556.3E-4229254IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.572229259IPR007087Zinc finger, C2H2
PROSITE patternPS000280231254IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.4E-8259286IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0033262286IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.471262286IPR007087Zinc finger, C2H2
PROSITE patternPS000280264286IPR007087Zinc finger, C2H2
SMARTSM003555294319IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280296319IPR007087Zinc finger, C2H2
SMARTSM0035514322343IPR015880Zinc finger, C2H2-like
SuperFamilySSF576679.96E-8335394No hitNo description
PROSITE profilePS5015710.97352382IPR007087Zinc finger, C2H2
SMARTSM003550.17352377IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.606.1E-5353377IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280354377IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.7E-5378403IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003556.5383409IPR015880Zinc finger, C2H2-like
PROSITE profilePS501578.704383409IPR007087Zinc finger, C2H2
PROSITE patternPS000280385409IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0006310anatomytassel floret
PO:0006339anatomyjuvenile vascular leaf
PO:0006340anatomyadult vascular leaf
PO:0006341anatomyprimary shoot system
PO:0006354anatomyear floret
PO:0006505anatomycentral spike of ear inflorescence
PO:0008018anatomytransition vascular leaf
PO:0009001anatomyfruit
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009054anatomyinflorescence bract
PO:0009066anatomyanther
PO:0009074anatomystyle
PO:0009084anatomypericarp
PO:0009089anatomyendosperm
PO:0020040anatomyleaf base
PO:0020104anatomyleaf sheath
PO:0020126anatomytassel inflorescence
PO:0020127anatomyprimary root
PO:0020136anatomyear inflorescence
PO:0020142anatomystem internode
PO:0020148anatomyshoot apical meristem
PO:0025142anatomyleaf tip
PO:0025287anatomyseedling coleoptile
PO:0001007developmental stagepollen development stage
PO:0001009developmental stageD pollen mother cell meiosis stage
PO:0001052developmental stagevascular leaf expansion stage
PO:0001053developmental stagevascular leaf post-expansion stage
PO:0001083developmental stageinflorescence development stage
PO:0001094developmental stageplant embryo coleoptilar stage
PO:0001095developmental stageplant embryo true leaf formation stage
PO:0001180developmental stageplant proembryo stage
PO:0007001developmental stageearly whole plant fruit ripening stage
PO:0007003developmental stageIL.03 full inflorescence length reached stage
PO:0007006developmental stageIL.00 inflorescence just visible stage
PO:0007015developmental stageradicle emergence stage
PO:0007016developmental stagewhole plant flowering stage
PO:0007022developmental stageseed imbibition stage
PO:0007026developmental stageFL.00 first flower(s) open stage
PO:0007031developmental stagemid whole plant fruit ripening stage
PO:0007032developmental stagewhole plant fruit formation stage up to 10%
PO:0007045developmental stagecoleoptile emergence stage
PO:0007063developmental stageLP.07 seven leaves visible stage
PO:0007065developmental stageLP.05 five leaves visible stage
PO:0007072developmental stageLP.18 eighteen leaves visible stage
PO:0007094developmental stageLP.01 one leaf visible stage
PO:0007101developmental stageLP.09 nine leaves visible stage
PO:0007104developmental stageLP.15 fifteen leaves visible stage
PO:0007106developmental stageLP.03 three leaves visible stage
PO:0007112developmental stage1 main shoot growth stage
PO:0007116developmental stageLP.11 eleven leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007633developmental stageendosperm development stage
PO:0021004developmental stageinflorescence initiation stage
Sequence ? help Back to Top
Protein Sequence    Length: 476 aa     Download sequence    Send to blast
MHGGTLELHP FLAPAFRRTT SLTTGAAAHT AAHCTPSVPR PRSALSARPP VARDARRTAP  60
SLLAAGDGTG GPLLGCAQAA RARSTPASVH LRQALLRTST HRMCSEVHVE GDASVGQKGC  120
KDIRRYKCEF CTVVRSKKCL IQAHMVAHHK DELDKSEIYN SDGEKIVHEQ EHRCQECGRC  180
FQKPAHLKQH MQSHSHERLF ICPLEDCPFS YKRKDHLNRH MLKHEGKLFS CTLDGCDMRF  240
SMKADMQRHV KEIHDSKNPH QFVCKEDGCN KVFRYSSKLK KHEESHVKLD YVEVVCCEPG  300
CMKMFRNVEY LRAHNQSCHQ YVQCEICGEK HLKKNIKRHL QSHDKVPSDG RMKCTFDGCE  360
HFFSNKSNLT KHVKACHDQL KPFKCGIVGC GKAFTYKHVR DNHETSGAHV YMEGDFEELD  420
EQLRARPRGG RKRKALTVET LTRKRVTISG EASSLDDGVE YLRWLLSGGD DSIDCQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A1e-1617637719188PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D1e-1617637719188PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1425433RPRGGRKRK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Zm.669470.0ear| meristem| ovary| shoot| tassel
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasGRMZM2G380515
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGRMZM2G380515_P02
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0383390.0BT038339.1 Zea mays full-length cDNA clone ZM_BFb0227N03 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008654475.10.0uncharacterized protein LOC100216772 isoform X2
SwissprotQ84MZ43e-94TF3A_ARATH; Transcription factor IIIA
TrEMBLK7V1N90.0K7V1N9_MAIZE; Pentatricopeptide repeat-containing protein
STRINGGRMZM2G380515_P020.0(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP23823882
Representative plantOGRP29811627
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.27e-87transcription factor IIIA