PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Tp57577_TGAC_v2_mRNA8769
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium
Family bZIP
Protein Properties Length: 322aa    MW: 35169.7 Da    PI: 8.0024
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Tp57577_TGAC_v2_mRNA8769genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_149.31.1e-15241302162
                               XXXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
                    bZIP_1   1 ekelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklkse 62 
                               +ke+kr +r+ +NR++A+  R+RKka++  Le++v  Le++N++Lk++l++l++e + l++ 
  Tp57577_TGAC_v2_mRNA8769 241 DKESKRLKRLLRNRVSAQQARERKKAYLSDLETRVNDLEKKNSELKEKLSTLQNENQMLRQI 302
                               689******************************************************99876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF578509.36E-3224103No hitNo description
Gene3DG3DSA:3.30.40.105.4E-2925108IPR013083Zinc finger, RING/FYVE/PHD-type
PfamPF145696.1E-3728103IPR027934Cellulose synthase, RING-type zinc finger
SMARTSM003382.4E-17241305IPR004827Basic-leucine zipper domain
PfamPF001704.6E-14242303IPR004827Basic-leucine zipper domain
PROSITE profilePS5021712.875243306IPR004827Basic-leucine zipper domain
Gene3DG3DSA:1.20.5.1702.4E-17245305No hitNo description
SuperFamilySSF579591.31E-13245303No hitNo description
CDDcd147041.18E-19246297No hitNo description
PROSITE patternPS000360248263IPR004827Basic-leucine zipper domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 322 aa     Download sequence    Send to blast
MNMEGIATGS HERNELVRVR NGSASGSKPL KNLNGQICQI CGDTVGLTAT GDVFVACHEC  60
PFPLCHPCYE YERKNGQSCL QCKTKYKIHK EGPRVKGDDD DEDDLRNEVK YGQGNNSKTG  120
WQWDEDADLS SSSGHDSQLQ NPHLVNGQLM SGEILGATSD TQSVQTTSGP LGQSENVHSR  180
PYVDQKQPGL ESDEEIRRVP EMGGESAGTS ASRKGTGSTA GPERAQGAGE GQKKRGRSPA  240
DKESKRLKRL LRNRVSAQQA RERKKAYLSD LETRVNDLEK KNSELKEKLS TLQNENQMLR  300
QILKNTTASR RGNNGGANNA E*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1weo_A6e-282495577cellulose synthase, catalytic subunit (IRX3)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtCatalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the primary cell wall formation. Required during embryogenesis for cell elongation, orientation of cell expansion and complex cell wall formations, such as interdigitated pattern of epidermal pavement cells, stomatal guard cells and trichomes. Plays a role in lateral roots formation, but seems not necessary for the development of tip-growing cells such as root hairs. The presence of each protein CESA1 and CESA6 is critical for cell expansion after germination. {ECO:0000269|PubMed:10987560, ECO:0000269|PubMed:11148287, ECO:0000269|PubMed:11732051, ECO:0000269|PubMed:11732056, ECO:0000269|PubMed:11901167, ECO:0000269|PubMed:12068120, ECO:0000269|PubMed:12481071, ECO:0000269|PubMed:17878302, ECO:0000269|PubMed:17878303, ECO:0000269|PubMed:9445479}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapTp57577_TGAC_v2_mRNA8769
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankFJ3741220.0FJ374122.1 Pisum sativum cultivar Torsdag LONG1 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013459310.10.0cellulose synthase A catalytic subunit 1 [UDP-forming]
SwissprotO489466e-55CESA1_ARATH; Cellulose synthase A catalytic subunit 1 [UDP-forming]
TrEMBLA0A2K3NQE50.0A0A2K3NQE5_TRIPR; Cellulose synthase A catalytic subunit 1
STRINGXP_004513402.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF70643248
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G11260.12e-46bZIP family protein
Publications ? help Back to Top
  1. Taylor NG,Scheible WR,Cutler S,Somerville CR,Turner SR
    The irregular xylem3 locus of Arabidopsis encodes a cellulose synthase required for secondary cell wall synthesis.
    Plant Cell, 1999. 11(5): p. 769-80
    [PMID:10330464]
  2. Holland N, et al.
    A comparative analysis of the plant cellulose synthase (CesA) gene family.
    Plant Physiol., 2000. 123(4): p. 1313-24
    [PMID:10938350]
  3. Peng L,Hocart CH,Redmond JW,Williamson RE
    Fractionation of carbohydrates in Arabidopsis root cell walls shows that three radial swelling loci are specifically involved in cellulose production.
    Planta, 2000. 211(3): p. 406-14
    [PMID:10987560]
  4. Fagard M, et al.
    PROCUSTE1 encodes a cellulose synthase required for normal cell elongation specifically in roots and dark-grown hypocotyls of Arabidopsis.
    Plant Cell, 2000. 12(12): p. 2409-2424
    [PMID:11148287]
  5. Richmond T
    Higher plant cellulose synthases.
    Genome Biol., 2000. 1(4): p. REVIEWS3001
    [PMID:11178255]
  6. Lane DR, et al.
    Temperature-sensitive alleles of RSW2 link the KORRIGAN endo-1,4-beta-glucanase to cellulose synthesis and cytokinesis in Arabidopsis.
    Plant Physiol., 2001. 126(1): p. 278-88
    [PMID:11351091]
  7. Peng L, et al.
    The experimental herbicide CGA 325'615 inhibits synthesis of crystalline cellulose and causes accumulation of non-crystalline beta-1,4-glucan associated with CesA protein.
    Plant Physiol., 2001. 126(3): p. 981-92
    [PMID:11457949]
  8. Scheible WR,Eshed R,Richmond T,Delmer D,Somerville C
    Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants.
    Proc. Natl. Acad. Sci. U.S.A., 2001. 98(18): p. 10079-84
    [PMID:11517344]
  9. Williamson RE, et al.
    Morphology of rsw1, a cellulose-deficient mutant of Arabidopsis thaliana.
    Protoplasma, 2001. 215(1-4): p. 116-27
    [PMID:11732051]
  10. Sugimoto K,Williamson RE,Wasteneys GO
    Wall architecture in the cellulose-deficient rsw1 mutant of Arabidopsis thaliana: microfibrils but not microtubules lose their transverse alignment before microfibrils become unrecognizable in the mitotic and elongation zones of roots.
    Protoplasma, 2001. 215(1-4): p. 172-83
    [PMID:11732056]
  11. Gillmor CS,Poindexter P,Lorieau J,Palcic MM,Somerville C
    Alpha-glucosidase I is required for cellulose biosynthesis and morphogenesis in Arabidopsis.
    J. Cell Biol., 2002. 156(6): p. 1003-13
    [PMID:11901167]
  12. Burn JE,Hocart CH,Birch RJ,Cork AC,Williamson RE
    Functional analysis of the cellulose synthase genes CesA1, CesA2, and CesA3 in Arabidopsis.
    Plant Physiol., 2002. 129(2): p. 797-807
    [PMID:12068120]
  13. Ellis C,Karafyllidis I,Wasternack C,Turner JG
    The Arabidopsis mutant cev1 links cell wall signaling to jasmonate and ethylene responses.
    Plant Cell, 2002. 14(7): p. 1557-66
    [PMID:12119374]
  14. Beeckman T, et al.
    Genetic complexity of cellulose synthase a gene function in Arabidopsis embryogenesis.
    Plant Physiol., 2002. 130(4): p. 1883-93
    [PMID:12481071]
  15. Burn JE, et al.
    The cellulose-deficient Arabidopsis mutant rsw3 is defective in a gene encoding a putative glucosidase II, an enzyme processing N-glycans during ER quality control.
    Plant J., 2002. 32(6): p. 949-60
    [PMID:12492837]
  16. Sugimoto K,Himmelspach R,Williamson RE,Wasteneys GO
    Mutation or drug-dependent microtubule disruption causes radial swelling without altering parallel cellulose microfibril deposition in Arabidopsis root cells.
    Plant Cell, 2003. 15(6): p. 1414-29
    [PMID:12782733]
  17. Kalluri UC,Joshi CP
    Differential expression patterns of two cellulose synthase genes are associated with primary and secondary cell wall development in aspen trees.
    Planta, 2004. 220(1): p. 47-55
    [PMID:15278458]
  18. Nühse TS,Stensballe A,Jensen ON,Peck SC
    Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database.
    Plant Cell, 2004. 16(9): p. 2394-405
    [PMID:15308754]
  19. Wang J,Howles PA,Cork AH,Birch RJ,Williamson RE
    Chimeric proteins suggest that the catalytic and/or C-terminal domains give CesA1 and CesA3 access to their specific sites in the cellulose synthase of primary walls.
    Plant Physiol., 2006. 142(2): p. 685-95
    [PMID:16891551]
  20. Bosca S, et al.
    Interactions between MUR10/CesA7-dependent secondary cellulose biosynthesis and primary cell wall structure.
    Plant Physiol., 2006. 142(4): p. 1353-63
    [PMID:17041031]
  21. Hématy K, et al.
    A receptor-like kinase mediates the response of Arabidopsis cells to the inhibition of cellulose synthesis.
    Curr. Biol., 2007. 17(11): p. 922-31
    [PMID:17540573]
  22. Persson S, et al.
    Genetic evidence for three unique components in primary cell-wall cellulose synthase complexes in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(39): p. 15566-71
    [PMID:17878302]
  23. Desprez T, et al.
    Organization of cellulose synthase complexes involved in primary cell wall synthesis in Arabidopsis thaliana.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(39): p. 15572-7
    [PMID:17878303]
  24. Kang JS, et al.
    Salt tolerance of Arabidopsis thaliana requires maturation of N-glycosylated proteins in the Golgi apparatus.
    Proc. Natl. Acad. Sci. U.S.A., 2008. 105(15): p. 5933-8
    [PMID:18408158]
  25. Wang J,Elliott JE,Williamson RE
    Features of the primary wall CESA complex in wild type and cellulose-deficient mutants of Arabidopsis thaliana.
    J. Exp. Bot., 2008. 59(10): p. 2627-37
    [PMID:18495638]
  26. Bischoff V,Cookson SJ,Wu S,Scheible WR
    Thaxtomin A affects CESA-complex density, expression of cell wall genes, cell wall composition, and causes ectopic lignification in Arabidopsis thaliana seedlings.
    J. Exp. Bot., 2009. 60(3): p. 955-65
    [PMID:19269997]
  27. Betancur L, et al.
    Phylogenetically distinct cellulose synthase genes support secondary wall thickening in arabidopsis shoot trichomes and cotton fiber.
    J Integr Plant Biol, 2010. 52(2): p. 205-20
    [PMID:20377682]
  28. Gu Y, et al.
    Identification of a cellulose synthase-associated protein required for cellulose biosynthesis.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(29): p. 12866-71
    [PMID:20616083]
  29. Chen S,Ehrhardt DW,Somerville CR
    Mutations of cellulose synthase (CESA1) phosphorylation sites modulate anisotropic cell expansion and bidirectional mobility of cellulose synthase.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(40): p. 17188-93
    [PMID:20855602]
  30. Bischoff V, et al.
    Phytochrome regulation of cellulose synthesis in Arabidopsis.
    Curr. Biol., 2011. 21(21): p. 1822-7
    [PMID:22036185]
  31. Harris DM, et al.
    Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1A903V and CESA3T942I of cellulose synthase.
    Proc. Natl. Acad. Sci. U.S.A., 2012. 109(11): p. 4098-103
    [PMID:22375033]
  32. Carroll A, et al.
    Complexes with mixed primary and secondary cellulose synthases are functional in Arabidopsis plants.
    Plant Physiol., 2012. 160(2): p. 726-37
    [PMID:22926318]
  33. Li S,Lei L,Gu Y
    Functional analysis of complexes with mixed primary and secondary cellulose synthases.
    Plant Signal Behav, 2013. 8(3): p. e23179
    [PMID:23299322]
  34. Fujita M, et al.
    The anisotropy1 D604N mutation in the Arabidopsis cellulose synthase1 catalytic domain reduces cell wall crystallinity and the velocity of cellulose synthase complexes.
    Plant Physiol., 2013. 162(1): p. 74-85
    [PMID:23532584]
  35. Sethaphong L, et al.
    Tertiary model of a plant cellulose synthase.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(18): p. 7512-7
    [PMID:23592721]
  36. Panteris E,Adamakis ID,Daras G,Rigas S
    Cortical microtubule patterning in roots of Arabidopsis thaliana primary cell wall mutants reveals the bidirectional interplay with cell expansion.
    Plant Signal Behav, 2018.
    [PMID:24717634]
  37. Boex-Fontvieille E, et al.
    Photosynthetic activity influences cellulose biosynthesis and phosphorylation of proteins involved therein in Arabidopsis leaves.
    J. Exp. Bot., 2014. 65(17): p. 4997-5010
    [PMID:25039072]
  38. Nikolovski N,Shliaha PV,Gatto L,Dupree P,Lilley KS
    Label-free protein quantification for plant Golgi protein localization and abundance.
    Plant Physiol., 2014. 166(2): p. 1033-43
    [PMID:25122472]
  39. Slabaugh E, et al.
    Computational and genetic evidence that different structural conformations of a non-catalytic region affect the function of plant cellulose synthase.
    J. Exp. Bot., 2014. 65(22): p. 6645-53
    [PMID:25262226]
  40. Gonneau M,Desprez T,Guillot A,Vernhettes S,Höfte H
    Catalytic subunit stoichiometry within the cellulose synthase complex.
    Plant Physiol., 2014. 166(4): p. 1709-12
    [PMID:25352273]
  41. Abu-Abied M, et al.
    Dissecting the contribution of microtubule behaviour in adventitious root induction.
    J. Exp. Bot., 2015. 66(9): p. 2813-24
    [PMID:25788735]
  42. Panteris E,Adamakis ID,Daras G,Rigas S
    Cortical microtubule patterning in roots of Arabidopsis thaliana primary cell wall mutants reveals the bidirectional interplay with cell expansion.
    Plant Signal Behav, 2015. 10(6): p. e1028701
    [PMID:26042727]
  43. Endler A, et al.
    A Mechanism for Sustained Cellulose Synthesis during Salt Stress.
    Cell, 2015. 162(6): p. 1353-64
    [PMID:26343580]
  44. Vandavasi VG, et al.
    A Structural Study of CESA1 Catalytic Domain of Arabidopsis Cellulose Synthesis Complex: Evidence for CESA Trimers.
    Plant Physiol., 2016. 170(1): p. 123-35
    [PMID:26556795]
  45. Slabaugh E, et al.
    The valine and lysine residues in the conserved FxVTxK motif are important for the function of phylogenetically distant plant cellulose synthases.
    Glycobiology, 2016. 26(5): p. 509-19
    [PMID:26646446]
  46. Jaipargas EA,Mathur N,Bou Daher F,Wasteneys GO,Mathur J
    High Light Intensity Leads to Increased Peroxule-Mitochondria Interactions in Plants.
    Front Cell Dev Biol, 2016. 4: p. 6
    [PMID:26870732]
  47. Zhang Y, et al.
    Golgi-localized STELLO proteins regulate the assembly and trafficking of cellulose synthase complexes in Arabidopsis.
    Nat Commun, 2016. 7: p. 11656
    [PMID:27277162]
  48. Kumar M, et al.
    S-Acylation of the cellulose synthase complex is essential for its plasma membrane localization.
    Science, 2016. 353(6295): p. 166-9
    [PMID:27387950]
  49. Hu Z, et al.
    Mitochondrial Defects Confer Tolerance against Cellulose Deficiency.
    Plant Cell, 2016. 28(9): p. 2276-2290
    [PMID:27543091]
  50. Li S, et al.
    Cellulose synthase complexes act in a concerted fashion to synthesize highly aggregated cellulose in secondary cell walls of plants.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(40): p. 11348-11353
    [PMID:27647923]
  51. Yang W, et al.
    PhCESA3 silencing inhibits elongation and stimulates radial expansion in petunia.
    Sci Rep, 2017. 7: p. 41471
    [PMID:28150693]
  52. Sánchez-Rodríguez C, et al.
    BRASSINOSTEROID INSENSITIVE2 negatively regulates cellulose synthesis in Arabidopsis by phosphorylating cellulose synthase 1.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(13): p. 3533-3538
    [PMID:28289192]
  53. Hill JL,Josephs C,Barnes WJ,Anderson CT,Tien M
    Longevity in vivo of primary cell wall cellulose synthases.
    Plant Mol. Biol., 2018. 96(3): p. 279-289
    [PMID:29388029]
  54. Hu H, et al.
    Cellulose Synthase Mutants Distinctively Affect Cell Growth and Cell Wall Integrity for Plant Biomass Production in Arabidopsis.
    Plant Cell Physiol., 2018. 59(6): p. 1144-1157
    [PMID:29514326]
  55. Arioli T, et al.
    Molecular analysis of cellulose biosynthesis in Arabidopsis.
    Science, 1998. 279(5351): p. 717-20
    [PMID:9445479]
  56. Nakagawa N,Sakurai N
    Increase in the amount of celA1 protein in tobacco BY-2 cells by a cellulose biosynthesis inhibitor, 2,6-dichlorobenzonitrile.
    Plant Cell Physiol., 1998. 39(7): p. 779-85
    [PMID:9729901]