PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thecc1EG001108t1

Common Name

TCM_001108

Organism

Theobroma cacao

Taxonomic ID

3641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

CAMTA

Protein Properties

Length: 1086aa MW: 123017 Da PI: 6.3523

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG001108t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	178.7	7e-56	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptf 94 ++ ++rwl++ ei++iL++++k++++ e+++ p+sgsl+L++rk++ryfrkDG++w+kkkdgktv+E+he+LK g+++vl+cyYah+e+n++f Thecc1EG001108t1 20 MEAQHRWLRPAEICEILKDYKKFHIAPEPAHMPPSGSLFLFDRKVLRYFRKDGHNWRKKKDGKTVKEAHERLKAGSIDVLHCYYAHGEDNENF 112 5569*************************************************************************************** PP CG-1 95 qrrcywlLeeelekivlvhylevk 118 qrr+yw+Lee+l++ivlvhy+evk Thecc1EG001108t1 113 QRRSYWMLEEDLSHIVLVHYREVK 136 *******************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	82.215	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	6.9E-77	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	8.3E-49	21	134	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	4.5E-6	503	590	IPR013783	Immunoglobulin-like fold
Pfam	PF01833	5.8E-7	504	589	IPR002909	IPT domain
SuperFamily	SSF81296	1.19E-18	504	590	IPR014756	Immunoglobulin E-set
PROSITE profile	PS50297	18.112	685	806	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	2.64E-13	685	794	No hit	No description
SuperFamily	SSF48403	1.15E-16	686	796	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	7.6E-17	691	800	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	6.2E-7	707	799	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.0046	735	764	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	9.912	735	767	IPR002110	Ankyrin repeat
SMART	SM00248	490	774	803	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	6.9E-8	905	960	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	0.16	909	931	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	8.352	911	939	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.0039	912	930	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.019	932	954	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.487	933	957	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.001	935	954	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1086 aa Download sequence Send to blast
MAETRRYGLS NQLDIEQILM EAQHRWLRPA EICEILKDYK KFHIAPEPAH MPPSGSLFLF 60 DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEDNE NFQRRSYWML 120 EEDLSHIVLV HYREVKGNRT NFNRIKETEE AIPYSQDTEG ILPNSEMESS VSSSFHPNNG 180 QIPSKTTDTT SLNSVQASEY EDAESDYNHQ ASSQFNSFLE LQQPVVGRVD SGFSDPYVPL 240 SHSNDYHGKP SGTGFQLTQP DKSREYNDAG LTYEPQKNLD FTSWEDVLEN CTPGVESAQH 300 QPPFSSTQRD TMGQLFNNSF LTKQEFDNQA PVQEEWQASE GDSSHLSKWP LNQKLHPDLR 360 YDLTFRFHEQ EVNHHVHPDK QHDNSMQNNE QIEPSNGKHG YALKPDPESH LTLEGKSINS 420 SAMRQHLFDG SLVEEGLKKL DSFNRWMSKE LGDVDESHMQ SSSGAYWDAV EGQNGVDVST 480 IPSQGQLDTF LLGPSLSQDQ LFSIIDFSPN WAYVGSEIKV LITGRFLKSR DEAENCKWSC 540 MFGEVEVPAE VIADGVLRCH TPIHKAGRVP FYVTCSNRLA CSEVREFEYR VNHMETMDYP 600 RSNTNEILDM RFGRLLCLGP RSPYSITYNV ADVSQLSDEI NSLLKEDIKE WDQMLMHNSA 660 EEISPEKMKE QLLQKLLKEK LRVWLLQKVA EGGKGPNILD DGGQGVIHFA AALGYDWALE 720 PTIVAGVSVN FRDVNGWTAL HWAASYGRER TVASLISLGA APGALTDPTP KYPLGRTPAD 780 LASTNGHKGI SGYLAESDLS FHLRSLNLDN QGNNDTVDSR ADAIQKILER STAPLGCGDA 840 SDGPSLKDSL AAVRNATQAA ARIHQVFRVQ SFQKRQLKEY GDGKFGMSNE RALSLIAVKS 900 NKPGQHDEHV QAAAIRIQNK FRGWKGRKEF LIIRQRIVKI QAHVRGHQVR KTYRKIVWSV 960 GILEKVILRW RRKGSGLRGF KPEALTEGPS IRAPPPKEDD YDFLKEGRKQ TEERLQKALA 1020 RVKSMAQNPA GRDQYSRMKN VVTEIQETKV MYDKVLSSTE TVLDEDLIDL EKLLDADTFM 1080 HTHLE*

Sequence ? help Back to Top

Protein Sequence Length: 1086 aa Download sequence Send to blast

MAETRRYGLS NQLDIEQILM EAQHRWLRPA EICEILKDYK KFHIAPEPAH MPPSGSLFLF  60
DRKVLRYFRK DGHNWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEDNE NFQRRSYWML  120
EEDLSHIVLV HYREVKGNRT NFNRIKETEE AIPYSQDTEG ILPNSEMESS VSSSFHPNNG  180
QIPSKTTDTT SLNSVQASEY EDAESDYNHQ ASSQFNSFLE LQQPVVGRVD SGFSDPYVPL  240
SHSNDYHGKP SGTGFQLTQP DKSREYNDAG LTYEPQKNLD FTSWEDVLEN CTPGVESAQH  300
QPPFSSTQRD TMGQLFNNSF LTKQEFDNQA PVQEEWQASE GDSSHLSKWP LNQKLHPDLR  360
YDLTFRFHEQ EVNHHVHPDK QHDNSMQNNE QIEPSNGKHG YALKPDPESH LTLEGKSINS  420
SAMRQHLFDG SLVEEGLKKL DSFNRWMSKE LGDVDESHMQ SSSGAYWDAV EGQNGVDVST  480
IPSQGQLDTF LLGPSLSQDQ LFSIIDFSPN WAYVGSEIKV LITGRFLKSR DEAENCKWSC  540
MFGEVEVPAE VIADGVLRCH TPIHKAGRVP FYVTCSNRLA CSEVREFEYR VNHMETMDYP  600
RSNTNEILDM RFGRLLCLGP RSPYSITYNV ADVSQLSDEI NSLLKEDIKE WDQMLMHNSA  660
EEISPEKMKE QLLQKLLKEK LRVWLLQKVA EGGKGPNILD DGGQGVIHFA AALGYDWALE  720
PTIVAGVSVN FRDVNGWTAL HWAASYGRER TVASLISLGA APGALTDPTP KYPLGRTPAD  780
LASTNGHKGI SGYLAESDLS FHLRSLNLDN QGNNDTVDSR ADAIQKILER STAPLGCGDA  840
SDGPSLKDSL AAVRNATQAA ARIHQVFRVQ SFQKRQLKEY GDGKFGMSNE RALSLIAVKS  900
NKPGQHDEHV QAAAIRIQNK FRGWKGRKEF LIIRQRIVKI QAHVRGHQVR KTYRKIVWSV  960
GILEKVILRW RRKGSGLRGF KPEALTEGPS IRAPPPKEDD YDFLKEGRKQ TEERLQKALA  1020
RVKSMAQNPA GRDQYSRMKN VVTEIQETKV MYDKVLSSTE TVLDEDLIDL EKLLDADTFM  1080
HTHLE*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007047945.2	0.0	PREDICTED: calmodulin-binding transcription activator 3
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A061DIL9	0.0	A0A061DIL9_THECC; Calmodulin-binding transcription activator protein with CG-1 and Ankyrin domains, putative isoform 1
STRING	EOX92102	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM8601	25	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Link Out ? help Back to Top
Phytozome	Thecc1EG001108t1
Entrez Gene	18611563

Publications ? help Back to Top
Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]