PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00018329-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family HD-ZIP
Protein Properties Length: 239aa    MW: 26874.8 Da    PI: 5.0177
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00018329-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox60.23.4e-1957110356
                            --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
               Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                            k+++++ +q+++Le+ Fe ++++  e++ +LA++lgL+ rqV vWFqNrRa++k
  SMil_00018329-RA_Salv  57 KKRRLSVDQVKALEKNFEVENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWK 110
                            566899***********************************************9 PP
2HD-ZIP_I/II129.11.7e-4156148193
            HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLr 88 
                            ekkrrls +qvk+LE++Fe e+kLeperKv+la+eLglqprqvavWFqnrRAR+ktkqlE+dy  Lk++++alk++ e+L++e+++L 
  SMil_00018329-RA_Salv  56 EKKRRLSVDQVKALEKNFEVENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWKTKQLERDYGLLKANHEALKHKYESLHRENQSLL 143
                            69************************************************************************************** PP

            HD-ZIP_I/II  89 eelke 93 
                            ++++e
  SMil_00018329-RA_Salv 144 NQIRE 148
                            99986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466892.44E-1948114IPR009057Homeodomain-like
PROSITE profilePS5007117.50852112IPR001356Homeobox domain
SMARTSM003896.3E-1855116IPR001356Homeobox domain
CDDcd000862.02E-1657113No hitNo description
PfamPF000462.2E-1657110IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.604.8E-2059119IPR009057Homeodomain-like
PRINTSPR000315.7E-68392IPR000047Helix-turn-helix motif
PROSITE patternPS00027087110IPR017970Homeobox, conserved site
PRINTSPR000315.7E-692108IPR000047Helix-turn-helix motif
PfamPF021832.3E-17112152IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 239 aa     Download sequence    Send to blast
MKRLSSSDSL GGLMSICPNS TVDVDEHNHG GNPMYTREFQ TMLEGLEEEE SGQISEKKRR  60
LSVDQVKALE KNFEVENKLE PERKVKLAQE LGLQPRQVAV WFQNRRARWK TKQLERDYGL  120
LKANHEALKH KYESLHRENQ SLLNQIRELN GKIGVKEEAS VSESEEKCDV EIDEGGGAME  180
HQENEMMGAV FGDFKDGSSD SDSSAILNED NNSPITSPAG SSTTTALTAD SRRPRRVLL
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1104112RRARWKTKQ
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that may act as growth regulators in response to water deficit. Interacts with the core sequence 5'-CAATTATTA-3' of promoters in response to ABA and in an ABI1-dependent manner. Involved in the negative regulation of the ABA signaling pathway. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By water deficit, by abscisic acid (ABA) and by salt stress. Self expression regulation. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416, ECO:0000269|PubMed:16055682}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011100030.13e-90homeobox-leucine zipper protein ATHB-6-like
SwissprotP466681e-62ATHB6_ARATH; Homeobox-leucine zipper protein ATHB-6
TrEMBLA0A2G9I4D61e-100A0A2G9I4D6_9LAMI; Transcription factor HEX
STRINGcassava4.1_012419m2e-83(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA27182453
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22430.14e-55homeobox protein 6
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]