PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00016070-RA_Salv
Common NameWRKY2
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family WRKY
Protein Properties Length: 526aa    MW: 57916.4 Da    PI: 7.6015
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00016070-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY102.81.9e-32209266260
                            --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS-- CS
                   WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhek 60 
                            dDgynWrKYGqK+vkgse+prsYY+Ct+a+C++kkkve++  d++++ei+Y+g+Hnh+k
  SMil_00016070-RA_Salv 209 DDGYNWRKYGQKQVKGSENPRSYYKCTFANCSMKKKVEKDL-DGQITEIVYKGNHNHPK 266
                            8****************************************.***************85 PP
2WRKY107.66.3e-34381439159
                            ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                   WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                            ldDgy+WrKYGqK+vkg+++prsYY+Ct+agCpv+k+ver+++dp+ v++tYeg+Hnh+
  SMil_00016070-RA_Salv 381 LDDGYRWRKYGQKVVKGNPNPRSYYKCTTAGCPVRKHVERASHDPRSVITTYEGKHNHD 439
                            59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.9E-27199267IPR003657WRKY domain
PROSITE profilePS5081123.388203267IPR003657WRKY domain
SuperFamilySSF1182903.53E-24205267IPR003657WRKY domain
SMARTSM007741.8E-34208266IPR003657WRKY domain
PfamPF031069.9E-25209265IPR003657WRKY domain
Gene3DG3DSA:2.20.25.807.0E-38366441IPR003657WRKY domain
SuperFamilySSF1182908.37E-30373441IPR003657WRKY domain
PROSITE profilePS5081138.905376441IPR003657WRKY domain
SMARTSM007741.7E-39381440IPR003657WRKY domain
PfamPF031061.9E-26382439IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009753Biological Processresponse to jasmonic acid
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 526 aa     Download sequence    Send to blast
MSSASFTSLL TSDHHSTTTS SAVGRGLGDR IAQRTGSGVP KFKSLPPPSL PITPPSAASP  60
SSWFAIPPGL SPAELLDSPI LLSASNILPS PTTGTYPIQG FGWNSSFNTN QQEESKLERN  120
NFSEFSFQTR KPLTSYNLGE ETWNYQQSAN QNVQSSVDKP ITKSEVKQMQ SYSPEVAAIQ  180
KNDQSCNAAQ IEYNHYNQNQ SSSQNRKSDD GYNWRKYGQK QVKGSENPRS YYKCTFANCS  240
MKKKVEKDLD GQITEIVYKG NHNHPKPQST RRSSSSSSAS SSVHHQSYSA HFNEISEQSY  300
GQDRIDSSAA TPDNSTISIG DDELEQSSQK SRSVGDEIDD EEPHPKRWKC ESENDGVSTV  360
GSRAVREPRV VVQTTSDIDI LDDGYRWRKY GQKVVKGNPN PRSYYKCTTA GCPVRKHVER  420
ASHDPRSVIT TYEGKHNHDI PAARGSGNGR PSINAGAAMA TRPTPLPNNS TYPIPVSGLR  480
PSLMEPQPGY GMGSYGYSSF GTYDDALFSR AKDEPKDDLF LESLLC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A5e-38200442878Probable WRKY transcription factor 4
2lex_A5e-38200442878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:26025535). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535). Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535). {ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:26025535}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048). Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416). Accumulates in response to jasmonic acid (MeJA) (By similarity). {ECO:0000250|UniProtKB:Q6B6R4, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKM8231250.0KM823125.1 Salvia miltiorrhiza WRKY protein (WRKY2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011080757.10.0probable WRKY transcription factor 25
SwissprotQ6IEQ71e-131WRK24_ORYSJ; WRKY transcription factor WRKY24
TrEMBLA0A0D5YAC00.0A0A0D5YAC0_SALMI; WRKY protein
STRINGEOY346310.0(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA22862460
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.12e-99WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  3. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  4. Zhang L, et al.
    Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.
    Plant Sci., 2015. 236: p. 214-22
    [PMID:26025535]