PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00001022-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family HD-ZIP
Protein Properties Length: 842aa    MW: 91914.5 Da    PI: 6.4339
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00001022-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.13e-182684357
                           --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
               Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                           k  ++t+eq+e+Le+++ ++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  SMil_00001022-RA_Salv 26 KYVRYTAEQVEALERVYSECPKPSSLRRQQLIRECpilcNIEPKQIKVWFQNRRCREKQ 84
                           56789****************************************************97 PP
2START154.39.9e-491653722204
                            HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT. CS
                  START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg. 88 
                            +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s+ + g a+ra+g+v  ++    +e+l+d++ W ++++++e+      g 
  SMil_00001022-RA_Salv 165 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQRRGGVAARACGLVSLEPS-KIAEILKDRPSWFRDCRSQEIFTMFPAGn 251
                            7899******************************************************.7777777777**********999999999 PP

                            .EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE CS
                  START  89 .galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvd 171
                             g+++l  ++++a+++l+p Rdf+++Ry+ +l+ g++v++++S++ +   p+    s++vRae+lpSg+li+p+++g+s +++v+h +
  SMil_00001022-RA_Salv 252 gGTIELLHTQTYAPTTLAPaRDFWTLRYTTSLENGSLVVCETSLSGTGAGPSaaaASQFVRAEMLPSGYLIRPCEGGGSIIHIVDHLN 339
                            9***********************************************99999999******************************** PP

                            --SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXX CS
                  START 172 lkgrlphwllrslvksglaegaktwvatlqrqc 204
                            l++++++++lr+l++s+ + ++k++ ++l++ +
  SMil_00001022-RA_Salv 340 LQAWSVPEVLRPLYESSKVVAQKMTISALRYIR 372
                            **************************9998765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.2242185IPR001356Homeobox domain
SMARTSM003892.6E-142389IPR001356Homeobox domain
SuperFamilySSF466893.42E-162487IPR009057Homeodomain-like
CDDcd000861.24E-152686No hitNo description
PfamPF000469.7E-162784IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.6E-182884IPR009057Homeodomain-like
CDDcd146867.79E-678117No hitNo description
PROSITE profilePS5084826.662155383IPR002913START domain
CDDcd088754.23E-67159375No hitNo description
SMARTSM002347.1E-39164374IPR002913START domain
Gene3DG3DSA:3.30.530.201.8E-19164355IPR023393START-like domain
SuperFamilySSF559619.2E-34164376No hitNo description
PfamPF018525.8E-46165372IPR002913START domain
PfamPF086703.2E-48697841IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 842 aa     Download sequence    Send to blast
MAMVAQHHRE RENSSGSINK HLDSGKYVRY TAEQVEALER VYSECPKPSS LRRQQLIREC  60
PILCNIEPKQ IKVWFQNRRC REKQRKESTR LQSVNRKLSA MNKLLMEEND RLQKQVSQLV  120
CENGYMRQQL QTASVPTTDA SSESAVTTPQ HSLRDANNPA GLLSIAEETL AEFLSKATGT  180
AVDWVQMPGM KPGPDSVGIF AISQRRGGVA ARACGLVSLE PSKIAEILKD RPSWFRDCRS  240
QEIFTMFPAG NGGTIELLHT QTYAPTTLAP ARDFWTLRYT TSLENGSLVV CETSLSGTGA  300
GPSAAAASQF VRAEMLPSGY LIRPCEGGGS IIHIVDHLNL QAWSVPEVLR PLYESSKVVA  360
QKMTISALRY IRQIAQETSG EVVYGLGRQP AVLRTFTQKL SRGFNDAING FNNDGWSILN  420
CDGAEDVVVA INSAKNLTAD SSVVSLLGGV LCAKASMLLQ NVPPAVLVRF LREHRSEWAD  480
FNVDAYAAMS LKSSTCSYPG TRPTRFTGTQ IIMPLGQTIE HEEMLEVVRL EGHSLTHEDA  540
FASRDVHLLQ MCSGVDETAV GACSELIFAP IDEMFPDDAP LLPSGFRIIP LDSKSGDSHD  600
VLTSHKTLDL TSSLEVGPAT SHGAENAGSS CNARSVLTIA FQFPFESNLH DNVATMARQY  660
VRSVISSVQR VATAISPSGL SPTAGPKVSP ASPEALTLAH WICQSYSYHV GTELLRSDSV  720
GGDSVLKTLW HHQDAILCCS LKALPVFIFA NQAGLDMLET TLVSLQDIAL DKIFDDSGRK  780
ALFSEFAKIM QEGFASLPGG ICTSTMGRHV SYEQAVVWKV FAAEESSSVH CLALSFVNWS  840
FV
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011089912.10.0homeobox-leucine zipper protein REVOLUTA
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A4D9B7A60.0A0A4D9B7A6_SALSN; Homeobox-leucine zipper protein
STRINGVIT_06s0004g02800.t010.0(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA45724140
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]