PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Solyc01g079620.2.1
Common Namemyb12, MYB12
Organism
Solanum lycopersicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family MYB
Protein Properties Length: 339aa    MW: 38567.4 Da    PI: 4.7253
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Solyc01g079620.2.1genomeITAGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding491.4e-151461148
                        TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
     Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                        rgrWT+eEd++l +++   G g+W++ ++  g+ R++k+c++rw +yl
  Solyc01g079620.2.1 14 RGRWTAEEDQILTNYIISNGEGSWRSLPKNAGLLRCGKSCRLRWINYL 61
                        8*******************************99************97 PP
2Myb_DNA-binding50.54.7e-1667112148
                         TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
     Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                         rg+ T +E+++++++++ lG++ W++Ia+++  gRt++++k++w+++l
  Solyc01g079620.2.1  67 RGNITSQEEDIIIKLHATLGNR-WSLIAEHLS-GRTDNEIKNYWNSHL 112
                         7999******************.*********.************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.4E-20564IPR009057Homeodomain-like
PROSITE profilePS5129415.387961IPR017930Myb domain
SuperFamilySSF466891.11E-2611108IPR009057Homeodomain-like
SMARTSM007173.9E-111363IPR001005SANT/Myb domain
PfamPF002492.6E-131461IPR001005SANT/Myb domain
CDDcd001671.53E-71661No hitNo description
PROSITE profilePS5129424.45162116IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.0E-2465116IPR009057Homeodomain-like
SMARTSM007171.6E-1566114IPR001005SANT/Myb domain
PfamPF002493.4E-1467112IPR001005SANT/Myb domain
CDDcd001671.92E-971112No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009651Biological Processresponse to salt stress
GO:0009723Biological Processresponse to ethylene
GO:0009733Biological Processresponse to auxin
GO:0009813Biological Processflavonoid biosynthetic process
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0009001anatomyfruit
PO:0009085anatomyexocarp
Sequence ? help Back to Top
Protein Sequence    Length: 339 aa     Download sequence    Send to blast
MGRTPCCEKV GIKRGRWTAE EDQILTNYII SNGEGSWRSL PKNAGLLRCG KSCRLRWINY  60
LRSDLKRGNI TSQEEDIIIK LHATLGNRWS LIAEHLSGRT DNEIKNYWNS HLSRKVDSLR  120
IPSDEKLPKA VVDLAKKGIP KPIKKSSISR PKNKKSNLLE KEALCCTNMP ACDSAMELMQ  180
EDLAKIEVPN SWAGPIEAKG SLSSDSDIEW PRLEEIMPDV VIDDEDKNTN FILNCFREEV  240
TSNNVGNSYS CIEEGNKKIS SDDEKIKLLM DWQDNDELVW PTLPWELETD IVPSWPQWDD  300
TDTNLLQNCT NDNNNYEEAT TMEINNQNHS TIVSWLLS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A1e-22141187110B-MYB
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1135144KKGIPKPIKK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Les.134730.0flower
Function -- GeneRIF ? help Back to Top
  1. These experiments demonstrate that the MYB12 transcription factor plays an important role in regulating the flavonoid pathway in tomato fruit; the SLMYB12 mutation may be a candidate for the y mutation.
    [PMID: 19906891]
  2. MYB12 role in flavonol metabolism and fruit color
    [PMID: 27208285]
  3. The authors suggest that SlMYB12 plays a positive role in the flavonol biosynthesis pathway in cherry tomatoes.[SlMYB12]
    [PMID: 29371612]
Cis-element ? help Back to Top
SourceLink
PlantRegMapSolyc01g079620.2.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEU4197480.0Solanum lycopersicum MYB12 (MYB12) mRNA, complete cds
GenBankFN5551260.0Solanum lycopersicum mRNA for Myb 12 transcription factor (myb12 gene), cultivar Moneyberg
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001234401.10.0Myb12 transcription factor
TrEMBLB4YAJ80.0B4YAJ8_SOLLC; MYB12
STRINGSolyc01g079620.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA12242154
Representative plantOGRP5171784
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G47460.11e-71myb domain protein 12
Publications ? help Back to Top
  1. Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments.
    Theor. Appl. Genet., 2005. 112(1): p. 72-84
    [PMID:16208505]
  2. Luo J, et al.
    AtMYB12 regulates caffeoyl quinic acid and flavonol synthesis in tomato: expression in fruit results in very high levels of both types of polyphenol.
    Plant J., 2008. 56(2): p. 316-26
    [PMID:18643978]
  3. Ballester AR, et al.
    Biochemical and molecular analysis of pink tomatoes: deregulated expression of the gene encoding transcription factor SlMYB12 leads to pink tomato fruit color.
    Plant Physiol., 2010. 152(1): p. 71-84
    [PMID:19906891]
  4. Fernandez-Moreno JP, et al.
    Characterization of a New Pink-Fruited Tomato Mutant Results in the Identification of a Null Allele of the SlMYB12 Transcription Factor.
    Plant Physiol., 2016. 171(3): p. 1821-36
    [PMID:27208285]
  5. Wang S, et al.
    SlMYB12 Regulates Flavonol Synthesis in Three Different Cherry Tomato Varieties.
    Sci Rep, 2018. 8(1): p. 1582
    [PMID:29371612]