PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Seita.2G091100.1.p
Common NameSETIT_029636mg
Organism
Setaria italica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria
Family AP2
Protein Properties Length: 508aa    MW: 53928.2 Da    PI: 8.445
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Seita.2G091100.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP254.23.7e-17183232155
                 AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                         s+y+GV++++++grW+++I+d      + k+++lg f+ta  Aa+a+++a+ k++g
  Seita.2G091100.1.p 183 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 232
                         78*******************......55************************998 PP
2AP242.51.6e-13275325155
                 AP2   1 sgykGVrwdkkrgrWvAeIrdpseng...krkrfslgkfgtaeeAakaaiaarkkleg 55 
                         s+y+GV+ +k  grW+A+       g    +k+++lg f+++ eAa+a+++a+ +++g
  Seita.2G091100.1.p 275 SKYRGVTLHK-CGRWEAR---M---GqllGKKYIYLGLFDSEIEAARAYDRAAIRFNG 325
                         89********.7******...5...334336**********99**********99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008472.4E-9183232IPR001471AP2/ERF domain
SuperFamilySSF541711.05E-15183241IPR016177DNA-binding domain
PROSITE profilePS5103217.754184240IPR001471AP2/ERF domain
SMARTSM003802.2E-31184246IPR001471AP2/ERF domain
CDDcd000181.40E-10184239No hitNo description
Gene3DG3DSA:3.30.730.106.5E-17184240IPR001471AP2/ERF domain
CDDcd000185.03E-25275335No hitNo description
PfamPF008473.8E-9275325IPR001471AP2/ERF domain
SuperFamilySSF541715.89E-17275334IPR016177DNA-binding domain
SMARTSM003801.2E-32276339IPR001471AP2/ERF domain
PROSITE profilePS5103216.081276333IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.105.1E-16276334IPR001471AP2/ERF domain
PRINTSPR003671.9E-6277288IPR001471AP2/ERF domain
PRINTSPR003671.9E-6315335IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 508 aa     Download sequence    Send to blast
MASPSIPFVP LTSHRAVPFA LGTTPPWPPP PRPDAAAARL LQEEEEAGVG GSRARSPAGL  60
ELEPMVLDLN AESPTAGSAS ATSSSSGVAG GGGGFFRFDL LGGSPDEEGC SPSPPVVTRQ  120
LFPSPHPYAA SPASDGSPPP GVAGASAHRA ADLGASAPAP AAAAPSSPAA GKKSRRGPRS  180
RSSQYRGVTF YRRTGRWESH IWDCGKQVYL GGFDTAHAAA RAYDRAAIKF RGLDADINFH  240
LKDYESDLKQ MRNWTKEEFV HILRRQSTGF ARGSSKYRGV TLHKCGRWEA RMGQLLGKKY  300
IYLGLFDSEI EAARAYDRAA IRFNGPDAVT NFDSSSYDGD VPLPPEIEKD VVDRDILDLN  360
LRISQPNVHD PKSDGILTGF GSNRDSPEAS SSIASQPIRP QWLVHPHSTL GSPQQPQLYA  420
SPPGFFVNLR EAPGMENYRT VEPAPQAFPP WAWQMQGSPA PLLPATAASS GFSTAAAAAT  480
AGVPPPPLGP SPFAGRHHHQ LRFPPTA*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor (By similarity). Involved in spikelet transition (Probable). Together with IDS1, controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes (PubMed:22003982). Prevents lemma and palea elongation as well as grain growth (PubMed:28066457). Regulates the transition from spikelet meristem to floral meristem, spikelet meristem determinancy and the floral organ development (PubMed:17144896). {ECO:0000250|UniProtKB:P47927, ECO:0000269|PubMed:17144896, ECO:0000269|PubMed:22003982, ECO:0000269|PubMed:28066457, ECO:0000305|PubMed:26631749}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSeita.2G091100.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Target of miR172 microRNA mediated cleavage, particularly during floral organ development. {ECO:0000269|PubMed:20017947, ECO:0000269|PubMed:22003982, ECO:0000305|PubMed:26631749, ECO:0000305|PubMed:28066457}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004955853.10.0floral homeotic protein APETALA 2 isoform X2
SwissprotQ8H4430.0AP23_ORYSJ; APETALA2-like protein 3
TrEMBLA0A368PWS20.0A0A368PWS2_SETIT; Uncharacterized protein
STRINGSi029636m0.0(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP24483890
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G28550.31e-88related to AP2.7
Publications ? help Back to Top
  1. Lee DY,An G
    Two AP2 family genes, supernumerary bract (SNB) and Osindeterminate spikelet 1 (OsIDS1), synergistically control inflorescence architecture and floral meristem establishment in rice.
    Plant J., 2012. 69(3): p. 445-61
    [PMID:22003982]
  2. Wang L, et al.
    Coordinated regulation of vegetative and reproductive branching in rice.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(50): p. 15504-9
    [PMID:26631749]
  3. Dai Z,Wang J,Zhu M,Miao X,Shi Z
    OsMADS1 Represses microRNA172 in Elongation of Palea/Lemma Development in Rice.
    Front Plant Sci, 2016. 7: p. 1891
    [PMID:28066457]