PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G28550.3
Common NameRAP2.7, TOE1
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family AP2
Protein Properties Length: 464aa    MW: 51157.1 Da    PI: 6.794
Description related to AP2.7
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G28550.3genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP253.65.7e-17152201155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  s+y+GV++++++grW+++I+d      + k+++lg f+ta  Aa+a+++a+ k++g
  AT2G28550.3 152 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 201
                  78*******************......55************************997 PP
2AP240.76.1e-13244293154
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkle 54 
                  s+y+GV+ +k  grW+A+   +     +k+++lg f+++ eAa+a+++a+ + +
  AT2G28550.3 244 SKYRGVTLHK-CGRWEARMGQF--L-GKKYIYLGLFDSEVEAARAYDKAAINTN 293
                  89********.7******5553..2.26**********99*********98765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008475.2E-9152201IPR001471AP2/ERF domain
SuperFamilySSF541711.5E-15152209IPR016177DNA-binding domain
PROSITE profilePS5103217.82153209IPR001471AP2/ERF domain
CDDcd000189.88E-11153208No hitNo description
SMARTSM003801.2E-32153215IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.108.1E-17153209IPR001471AP2/ERF domain
PfamPF008473.2E-8244291IPR001471AP2/ERF domain
SuperFamilySSF541712.55E-16244304IPR016177DNA-binding domain
CDDcd000187.45E-23244304No hitNo description
PROSITE profilePS5103215.409245302IPR001471AP2/ERF domain
SMARTSM003802.5E-29245308IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.5E-15245303IPR001471AP2/ERF domain
PRINTSPR003679.0E-6246257IPR001471AP2/ERF domain
PRINTSPR003679.0E-6284304IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
Sequence ? help Back to Top
Protein Sequence    Length: 464 aa     Download sequence    Send to blast
MLDLNLNADS PESTQYGGDS YLDRQTSDNS AGNRVEESGT STSSVINADG DEDSCSTRAF  60
TLSFDILKVG SSSGGDESPA ASASVTKEFF PVSGDCGHLR DVEGSSSSRN WIDLSFDRIG  120
DGETKLVTPV PTPAPVPAQV KKSRRGPRSR SSQYRGVTFY RRTGRWESHI WDCGKQVYLG  180
GFDTAHAAAR AYDRAAIKFR GVDADINFTL GDYEEDMKQV QNLSKEEFVH ILRRQSTGFS  240
RGSSKYRGVT LHKCGRWEAR MGQFLGKKYI YLGLFDSEVE AARAYDKAAI NTNGREAVTN  300
FEMSSYQNEI NSESNNSEID LNLGISLSTG NAPKQNGRLF HFPSNTYETQ RGVSLRIDNE  360
YMGKPVNTPL PYGSSDHRLY WNGACPSYNN PAEGRATEKR SEAEGMMSNW GWQRPGQTSA  420
VRPQPPGPQP PPLFSVAAAS SGFSHFRPQP PNDNATRGYF YPHP
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.140090.0vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible264057_at0.0
Expression AtlasAT2G28550-
AtGenExpressAT2G28550-
ATTED-IIAT2G28550-
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay. {ECO:0000250, ECO:0000269|PubMed:14555699}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00615PBM24477691Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G28550.3
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR172a-2/EAT. {ECO:0000269|PubMed:14555699}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G65480(R)
Interaction ? help Back to Top
Source Intact With
BioGRIDAT2G37260, AT5G16560, AT5G60120, AT1G14920
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G28550
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF3250740.0AF325074.1 Arabidopsis thaliana putative AP2 domain transcription factor (At2g28550) mRNA, complete cds.
GenBankAY0508150.0AY050815.1 Arabidopsis thaliana putative AP2 domain transcription factor (At2g28550) mRNA, complete cds.
GenBankAY0914180.0AY091418.1 Arabidopsis thaliana putative AP2 domain transcription factor (At2g28550) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001189625.10.0related to AP2.7
SwissprotQ9SK030.0RAP27_ARATH; Ethylene-responsive transcription factor RAP2-7
TrEMBLF4IIR30.0F4IIR3_ARATH; Related to AP2.7
STRINGAT2G28550.30.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58612747
Representative plantOGRP4971784
Publications ? help Back to Top
  1. Krizek BA,Prost V,Macias A
    AINTEGUMENTA promotes petal identity and acts as a negative regulator of AGAMOUS.
    Plant Cell, 2000. 12(8): p. 1357-66
    [PMID:10948255]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Kreps JA, et al.
    Transcriptome changes for Arabidopsis in response to salt, osmotic, and cold stress.
    Plant Physiol., 2002. 130(4): p. 2129-41
    [PMID:12481097]
  4. Kasschau KD, et al.
    P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA unction.
    Dev. Cell, 2003. 4(2): p. 205-17
    [PMID:12586064]
  5. Hudson ME,Lisch DR,Quail PH
    The FHY3 and FAR1 genes encode transposase-related proteins involved in regulation of gene expression by the phytochrome A-signaling pathway.
    Plant J., 2003. 34(4): p. 453-71
    [PMID:12753585]
  6. Aukerman MJ,Sakai H
    Regulation of flowering time and floral organ identity by a MicroRNA and its APETALA2-like target genes.
    Plant Cell, 2003. 15(11): p. 2730-41
    [PMID:14555699]
  7. Schmid M, et al.
    Dissection of floral induction pathways using global expression analysis.
    Development, 2003. 130(24): p. 6001-12
    [PMID:14573523]
  8. Tepperman JM, et al.
    Expression profiling of phyB mutant demonstrates substantial contribution of other phytochromes to red-light-regulated gene expression during seedling de-etiolation.
    Plant J., 2004. 38(5): p. 725-39
    [PMID:15144375]
  9. Kawaguchi R,Girke T,Bray EA,Bailey-Serres J
    Differential mRNA translation contributes to gene regulation under non-stress and dehydration stress conditions in Arabidopsis thaliana.
    Plant J., 2004. 38(5): p. 823-39
    [PMID:15144383]
  10. Vogel JT,Zarka DG,Van Buskirk HA,Fowler SG,Thomashow MF
    Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis.
    Plant J., 2005. 41(2): p. 195-211
    [PMID:15634197]
  11. Masaki T, et al.
    ACTIVATOR of Spomin::LUC1/WRINKLED1 of Arabidopsis thaliana transactivates sugar-inducible promoters.
    Plant Cell Physiol., 2005. 46(4): p. 547-56
    [PMID:15753106]
  12. Hecht V, et al.
    Conservation of Arabidopsis flowering genes in model legumes.
    Plant Physiol., 2005. 137(4): p. 1420-34
    [PMID:15778459]
  13. Axtell MJ,Bartel DP
    Antiquity of microRNAs and their targets in land plants.
    Plant Cell, 2005. 17(6): p. 1658-73
    [PMID:15849273]
  14. Nawy T, et al.
    Transcriptional profile of the Arabidopsis root quiescent center.
    Plant Cell, 2005. 17(7): p. 1908-25
    [PMID:15937229]
  15. Nole-Wilson S,Tranby TL,Krizek BA
    AINTEGUMENTA-like (AIL) genes are expressed in young tissues and may specify meristematic or division-competent states.
    Plant Mol. Biol., 2005. 57(5): p. 613-28
    [PMID:15988559]
  16. Kim S,Soltis PS,Wall K,Soltis DE
    Phylogeny and domain evolution in the APETALA2-like gene family.
    Mol. Biol. Evol., 2006. 23(1): p. 107-20
    [PMID:16151182]
  17. Mlotshwa S, et al.
    Ectopic DICER-LIKE1 expression in P1/HC-Pro Arabidopsis rescues phenotypic anomalies but not defects in microRNA and silencing pathways.
    Plant Cell, 2005. 17(11): p. 2873-85
    [PMID:16214897]
  18. Lee BH,Henderson DA,Zhu JK
    The Arabidopsis cold-responsive transcriptome and its regulation by ICE1.
    Plant Cell, 2005. 17(11): p. 3155-75
    [PMID:16214899]
  19. Würschum T,Gross-Hardt R,Laux T
    APETALA2 regulates the stem cell niche in the Arabidopsis shoot meristem.
    Plant Cell, 2006. 18(2): p. 295-307
    [PMID:16387832]
  20. Jung J, et al.
    The barley ERF-type transcription factor HvRAF confers enhanced pathogen resistance and salt tolerance in Arabidopsis.
    Planta, 2007. 225(3): p. 575-88
    [PMID:16937017]
  21. Jung JH, et al.
    The GIGANTEA-regulated microRNA172 mediates photoperiodic flowering independent of CONSTANS in Arabidopsis.
    Plant Cell, 2007. 19(9): p. 2736-48
    [PMID:17890372]
  22. Jackson SD
    Plant responses to photoperiod.
    New Phytol., 2009. 181(3): p. 517-31
    [PMID:19154317]
  23. Glazińska P,Zienkiewicz A,Wojciechowski W,Kopcewicz J
    The putative miR172 target gene InAPETALA2-like is involved in the photoperiodic flower induction of Ipomoea nil.
    J. Plant Physiol., 2009. 166(16): p. 1801-13
    [PMID:19560230]
  24. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  25. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  26. Han Y,Zhang X,Wang W,Wang Y,Ming F
    The suppression of WRKY44 by GIGANTEA-miR172 pathway is involved in drought response of Arabidopsis thaliana.
    PLoS ONE, 2013. 8(11): p. e73541
    [PMID:24223111]
  27. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
    [PMID:25118255]
  28. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  29. Klucher KM,Chow H,Reiser L,Fischer RL
    The AINTEGUMENTA gene of Arabidopsis required for ovule and female gametophyte development is related to the floral homeotic gene APETALA2.
    Plant Cell, 1996. 8(2): p. 137-53
    [PMID:8742706]
  30. Okamuro JK,Caster B,Villarroel R,Van Montagu M,Jofuku KD
    The AP2 domain of APETALA2 defines a large new family of DNA binding proteins in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 1997. 94(13): p. 7076-81
    [PMID:9192694]
  31. Schneitz K,Baker SC,Gasser CS,Redweik A
    Pattern formation and growth during floral organogenesis: HUELLENLOS and AINTEGUMENTA are required for the formation of the proximal region of the ovule primordium in Arabidopsis thaliana.
    Development, 1998. 125(14): p. 2555-63
    [PMID:9636071]