PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676783686
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family C2H2
Protein Properties Length: 383aa    MW: 44379.3 Da    PI: 6.707
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676783686genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H210.80.001582104323
                ET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                C+   Cgk+F + s L++H   H
  676783686  82 CSyeGCGKTFFDVSALRKHSHIH 104
                77779**************7766 PP
2zf-C2H214.50.0001109133123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                y+C    C k F ++s LkrH   H
  676783686 109 YVCDypGCEKKFLDSSKLKRHWLIH 133
                89*******************9988 PP
3zf-C2H220.51.3e-06139163123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                ++C+   Cgk Fs   nL++H++tH
  676783686 139 FVCTyeGCGKAFSLDFNLRSHMKTH 163
                89**********************9 PP
4zf-C2H213.50.00022169194123
                EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                + Cp   Cgk++ + + Lk+H    H
  676783686 169 HICPysGCGKRYAHEYKLKNHVAAyH 194
                68*******************87666 PP
5zf-C2H212.90.00032232257123
                EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                y Cp   C k + + + Lk H+++ H
  676783686 232 YACPyeGCEKAYIHEYKLKLHLKReH 257
                89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.603.3E-1475106IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.006480104IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.94980109IPR007087Zinc finger, C2H2
PROSITE patternPS00028082104IPR007087Zinc finger, C2H2
SuperFamilySSF576671.71E-883133No hitNo description
Gene3DG3DSA:3.30.160.602.4E-14107129IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.279109138IPR007087Zinc finger, C2H2
SMARTSM003550.0057109133IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280111133IPR007087Zinc finger, C2H2
SuperFamilySSF576672.02E-14120174No hitNo description
Gene3DG3DSA:3.30.160.601.7E-19130165IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.757139168IPR007087Zinc finger, C2H2
SMARTSM003557.2E-4139163IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280141163IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.6E-7166190IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0074169194IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280171194IPR007087Zinc finger, C2H2
SuperFamilySSF576671.06E-5225255No hitNo description
Gene3DG3DSA:3.30.160.605.0E-9227254IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.016232259IPR007087Zinc finger, C2H2
SMARTSM003550.012232257IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280234257IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 383 aa     Download sequence    Send to blast
MEQQQHYPYH NPFERRPILK SKAPAVKWIK EWVPQDIVAT GGKCYLRKWV TEETVKRLKE  60
KEKEPEVPEP EPEPTTEVLF LCSYEGCGKT FFDVSALRKH SHIHGERQYV CDYPGCEKKF  120
LDSSKLKRHW LIHTGARDFV CTYEGCGKAF SLDFNLRSHM KTHSQENYHI CPYSGCGKRY  180
AHEYKLKNHV AAYHEKNAAG ETPKYTPPTE KVARTPKTPA TVYATATLER PYACPYEGCE  240
KAYIHEYKLK LHLKREHPGH LLEENAENPT PHKHELEEGS DQDFYRKHAS NGKSQAHKQQ  300
SRAKPNMRTP PAKAGKKGST SSPAKARIAK KPWQVKETFE GEREQEEEED SEETEEDREN  360
VDDGWRFGGN NEEDDDEETE DED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-35821938117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676783686
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013702531.10.0zinc finger transcription factor YY1-like
SwissprotQ2V3L30.0YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A3P6D7V80.0A0A3P6D7V8_BRACM; Uncharacterized protein
STRINGBo00829s040.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58592846
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.10.0C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]