PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT4G06634.1

Common Name

AtYY1, F8H12, YY1

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

C2H2

Protein Properties

Length: 387aa MW: 44703.4 Da PI: 6.47

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT4G06634.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	10.8	0.0016	81	103	3	23
ET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 3 Cp..dCgksFsrksnLkrHirtH 23 C+ Cgk+F + s L++H H AT4G06634.1 81 CSydGCGKTFFDVSALRKHSHIH 103 78889**************7766 PP
2	zf-C2H2	17	1.7e-05	108	132	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 y+C Cgk F ++s LkrH H AT4G06634.1 108 YVCDqeGCGKKFLDSSKLKRHYLIH 132 99*******************9988 PP
3	zf-C2H2	20.1	1.7e-06	138	162	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 y C+ Cgk Fs nL++H++tH AT4G06634.1 138 YICTyeGCGKAFSLDFNLRSHMKTH 162 899999******************9 PP
4	zf-C2H2	12.9	0.00033	230	255	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y Cp C k + + + Lk H+++ H AT4G06634.1 230 YACPyeGCEKAYIHEYKLKLHLKReH 255 89*********************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	3.7E-14	74	105	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.949	79	108	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0053	79	103	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	81	103	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.69E-9	82	132	No hit	No description
Gene3D	G3DSA:3.30.160.60	4.9E-14	106	130	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	14.274	108	137	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0011	108	132	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	110	132	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	3.55E-15	119	175	No hit	No description
Gene3D	G3DSA:3.30.160.60	5.9E-21	131	164	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	5.2E-4	138	162	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.84	138	167	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	140	162	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	9.8E-6	165	189	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.12	168	193	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	170	193	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.33E-5	225	253	No hit	No description
Gene3D	G3DSA:3.30.160.60	6.7E-9	226	252	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.012	230	255	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.328	230	260	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	232	255	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000293	anatomy	guard cell

Sequence ? help Back to Top
Protein Sequence Length: 387 aa Download sequence Send to blast
MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATG GKCHLHKWVT EDTFSRLKEK 60 EKEPDVPEPE PEPTTEILFL CSYDGCGKTF FDVSALRKHS HIHGERQYVC DQEGCGKKFL 120 DSSKLKRHYL IHTGERNYIC TYEGCGKAFS LDFNLRSHMK THSQENYHIC PYSGCVKRYA 180 HEYKLKNHVA AYHEKNGGGE TPKYTPPAEK VLRTVKTPAT VCGPSSDRPY ACPYEGCEKA 240 YIHEYKLKLH LKREHPGHLQ EENADTPTLN KHNGNDRNEI DDGSDQDVYR KHASNGKGQT 300 HKQQSRAKPN MRTPPAKVGK KGSTSSPAKA RIAKKPWQAK ETFEEVEREE EEDSEETEED 360 RDNVEDGWRF GENNEDDDDD EETEYED

Sequence ? help Back to Top

Protein Sequence Length: 387 aa Download sequence Send to blast

MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATG GKCHLHKWVT EDTFSRLKEK  60
EKEPDVPEPE PEPTTEILFL CSYDGCGKTF FDVSALRKHS HIHGERQYVC DQEGCGKKFL  120
DSSKLKRHYL IHTGERNYIC TYEGCGKAFS LDFNLRSHMK THSQENYHIC PYSGCVKRYA  180
HEYKLKNHVA AYHEKNGGGE TPKYTPPAEK VLRTVKTPAT VCGPSSDRPY ACPYEGCEKA  240
YIHEYKLKLH LKREHPGHLQ EENADTPTLN KHNGNDRNEI DDGSDQDVYR KHASNGKGQT  300
HKQQSRAKPN MRTPPAKVGK KGSTSSPAKA RIAKKPWQAK ETFEEVEREE EEDSEETEED  360
RDNVEDGWRF GENNEDDDDD EETEYED

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ubd_C	8e-37	81	192	8	117	PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.47264	0.0	inflorescence\| silique

Expression -- Microarray ? help Back to Top
Source	ID
Expression Atlas	AT4G06634
AtGenExpress	AT4G06634

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269\|PubMed:26961720}.
Uniprot	TISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269\|PubMed:26961720}.

Functional Description ? help Back to Top
Source	Description
UniProt	Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269\|PubMed:22508367, ECO:0000269\|PubMed:24451981, ECO:0000269\|PubMed:26961720}.

Function -- GeneRIF ? help Back to Top
genome-wide target gene analysis revealed that AtYY1 was involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism, and stress response[AtYY1] [PMID: 22508367]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT4G06634.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269\|PubMed:26961720}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT4G06634

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB073162	0.0	AB073162.1 Arabidopsis thaliana DNA, chromosome 4 centromere region, BAC clone:F8H12.
GenBank	CP002687	0.0	CP002687.1 Arabidopsis thaliana chromosome 4 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_849323.1	0.0	zinc finger (C2H2 type) family protein
Swissprot	Q2V3L3	0.0	YY1_ARATH; Zinc finger transcription factor YY1
TrEMBL	A0A178V3M9	0.0	A0A178V3M9_ARATH; Uncharacterized protein
STRING	AT4G06634.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5859	28	46
Representative plant	OGRP3856	16	26

Link Out ? help Back to Top
Phytozome	AT4G06634.1
Entrez Gene	826093
iHOP	AT4G06634
wikigenes	AT4G06634

Publications ? help Back to Top
Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4. DNA Res., 2001. 8(6): p. 285-90 [PMID:11853315] Reiland S, et al. Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks. Plant Physiol., 2009. 150(2): p. 889-903 [PMID:19376835] Rehrauer H, et al. AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling. Plant Physiol., 2010. 152(2): p. 487-99 [PMID:20032078] Wu X,Cheng Y,Li T,Wang Z,Liu JY In vitro identification of DNA-binding motif for the new zinc finger protein AtYY1. Acta Biochim. Biophys. Sin. (Shanghai), 2012. 44(6): p. 483-9 [PMID:22508367] Lai Z, et al. MED18 interaction with distinct transcription factors regulates multiple plant functions. Nat Commun, 2014. 5: p. 3064 [PMID:24451981] Bieluszewski T, et al. AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex. BMC Plant Biol., 2015. 15: p. 75 [PMID:25849764] Li T,Wu XY,Li H,Song JH,Liu JY A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network. Mol Plant, 2016. 9(5): p. 650-661 [PMID:26961720] Wu XY,Li T A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response. Front Plant Sci, 2017. 8: p. 323 [PMID:28348572]