PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676755576

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bHLH

Protein Properties

Length: 1183aa MW: 134630 Da PI: 7.9278

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676755576	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.7	1e-08	61	106	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++h +ErrRR riN f++Lr++lP+++ +Ka +L ++v+Y ++L 676755576 61 KKHRDAERRRRLRINCQFATLRTILPNLV------KDKAYVLGETVRYFNEL 106 679************************83......57888888888888776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.62E-9	52	112	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	9.794	58	106	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.1E-9	61	111	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.0E-6	61	106	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.8E-7	64	112	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF54695	1.02E-8	467	572	IPR011333	SKP1/BTB/POZ domain
Gene3D	G3DSA:3.30.710.10	8.4E-9	468	573	No hit	No description
PROSITE profile	PS50005	5.841	677	710	IPR019734	Tetratricopeptide repeat
SuperFamily	SSF48452	6.58E-14	679	712	IPR011990	Tetratricopeptide-like helical domain
Gene3D	G3DSA:1.25.40.10	2.1E-19	679	706	IPR011990	Tetratricopeptide-like helical domain
Gene3D	G3DSA:1.25.40.10	2.1E-19	769	874	IPR011990	Tetratricopeptide-like helical domain
PROSITE profile	PS50005	5.812	806	839	IPR019734	Tetratricopeptide repeat
SMART	SM00028	7.4	806	839	IPR019734	Tetratricopeptide repeat
SuperFamily	SSF48452	6.58E-14	808	841	IPR011990	Tetratricopeptide-like helical domain
SuperFamily	SSF48452	6.58E-14	900	1035	IPR011990	Tetratricopeptide-like helical domain
SMART	SM00028	120	932	965	IPR019734	Tetratricopeptide repeat
Gene3D	G3DSA:1.25.40.10	2.1E-19	934	1070	IPR011990	Tetratricopeptide-like helical domain
SuperFamily	SSF48452	3.57E-13	990	1173	IPR011990	Tetratricopeptide-like helical domain
SMART	SM00028	0.28	1006	1039	IPR019734	Tetratricopeptide repeat
PROSITE profile	PS50005	8.113	1006	1039	IPR019734	Tetratricopeptide repeat
Gene3D	G3DSA:1.25.40.10	2.1E-10	1071	1178	IPR011990	Tetratricopeptide-like helical domain
PROSITE profile	PS50005	6.815	1102	1135	IPR019734	Tetratricopeptide repeat
SMART	SM00028	0.22	1135	1168	IPR019734	Tetratricopeptide repeat

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 1183 aa Download sequence Send to blast
MVLLQHLEQR MSPISRCYNP TTYSTTMGRN FFPCATTSSK LFSKDFSAAK PKVESKEAAA 60 KKHRDAERRR RLRINCQFAT LRTILPNLVK DKAYVLGETV RYFNELKKMV KDIPTTPALE 120 DDFRLGYCNN KDLARVVFSC SDREGLMSEV AESIKAAKAK AVRAEIMTIG GRTKCALFIK 180 GVNGNEGLVR LKKSLKPLVN GDNESVPLSK TNNESWKLSV QSLQLLGFFL IDWLKMQPNL 240 FTAMRSLKFI EGCKGTHVYA LNPSSAPPPP PPIPTNAGGV GEKLLQHLQD HLRVNSIRSK 300 SSRTYQPPNR KNVVVSRDSL LPYGLPVTDQ LEPQIDPCLK FVDLIDKLAE IYRQIENCLE 360 FEKSDAYLEQ CAIFRGLSDP KLFRRSLRSA RQHAVNVHTK VVVASWLRYE RREDELIGTT 420 SIDCCGRNLE CPKATLVSGY DPESVYDHCV CSGAYVRSET SRDDDVSECS TSEVDYDMSF 480 CIGDDEVPCV RYKIASLSRP FKAMLYGGFR EMKRSVINFT HNGISVEGMR AAERFSRIQK 540 VEIFPPTIVL ELLRLANRFC CDELKSACDL HLARLVDNLD DAMLLMEYGL EEAAYLLVAA 600 CLQVFLRELP SSMHNSNVVK ILCSVEGRER LELVGHASFT LYLFLSHVAM EDDMISNTTV 660 MVLECLVECA VDTWQKQLAC HQLGVVMLER KEYKDAQRWF DYAVEAGHTY SLVGVARSKF 720 KRGHRYSAYK IMNSLISECS ATGWMHQERS MYCNGKEKLL DMDFATDLDP TLTFPYKFRA 780 VSLVEKSQFG AAVAELNKIM GFKVSPDCLE MRAWISIVME NYEGALKDIR ALLTLEPNFL 840 MFNKKIHGDH MVELLRPMVQ KWNQADCWMQ LYDRWSSVDD IGSLAVVHHM LAHDPWKSLL 900 RFRQSLLLLR LNCQKAAMRS LRLARNHSKS EHERLVYEGW ILYDTGHREE ALAKAEESIS 960 IQRSFEAYFL KAYVLADSTL DPESSKYVIQ LLEEALRCPS DGLRKGQALN NLGSVYVDCD 1020 KLDLAADCYM NALNIKHTRA HQGLARVYHL KNQRKAAYNE MTKLIKKAQN NASAFEKRSE 1080 YCDRDMAHGD LGMATQLDPL RTYPYRYRAA VLMDDRKESE AVEEISKAIA FKPDLQLLHL 1140 RAAFFDSMRE SADAIRDCEA ALSLDPSHTD TINLYHKARE PQS

Sequence ? help Back to Top

Protein Sequence Length: 1183 aa Download sequence Send to blast

MVLLQHLEQR MSPISRCYNP TTYSTTMGRN FFPCATTSSK LFSKDFSAAK PKVESKEAAA  60
KKHRDAERRR RLRINCQFAT LRTILPNLVK DKAYVLGETV RYFNELKKMV KDIPTTPALE  120
DDFRLGYCNN KDLARVVFSC SDREGLMSEV AESIKAAKAK AVRAEIMTIG GRTKCALFIK  180
GVNGNEGLVR LKKSLKPLVN GDNESVPLSK TNNESWKLSV QSLQLLGFFL IDWLKMQPNL  240
FTAMRSLKFI EGCKGTHVYA LNPSSAPPPP PPIPTNAGGV GEKLLQHLQD HLRVNSIRSK  300
SSRTYQPPNR KNVVVSRDSL LPYGLPVTDQ LEPQIDPCLK FVDLIDKLAE IYRQIENCLE  360
FEKSDAYLEQ CAIFRGLSDP KLFRRSLRSA RQHAVNVHTK VVVASWLRYE RREDELIGTT  420
SIDCCGRNLE CPKATLVSGY DPESVYDHCV CSGAYVRSET SRDDDVSECS TSEVDYDMSF  480
CIGDDEVPCV RYKIASLSRP FKAMLYGGFR EMKRSVINFT HNGISVEGMR AAERFSRIQK  540
VEIFPPTIVL ELLRLANRFC CDELKSACDL HLARLVDNLD DAMLLMEYGL EEAAYLLVAA  600
CLQVFLRELP SSMHNSNVVK ILCSVEGRER LELVGHASFT LYLFLSHVAM EDDMISNTTV  660
MVLECLVECA VDTWQKQLAC HQLGVVMLER KEYKDAQRWF DYAVEAGHTY SLVGVARSKF  720
KRGHRYSAYK IMNSLISECS ATGWMHQERS MYCNGKEKLL DMDFATDLDP TLTFPYKFRA  780
VSLVEKSQFG AAVAELNKIM GFKVSPDCLE MRAWISIVME NYEGALKDIR ALLTLEPNFL  840
MFNKKIHGDH MVELLRPMVQ KWNQADCWMQ LYDRWSSVDD IGSLAVVHHM LAHDPWKSLL  900
RFRQSLLLLR LNCQKAAMRS LRLARNHSKS EHERLVYEGW ILYDTGHREE ALAKAEESIS  960
IQRSFEAYFL KAYVLADSTL DPESSKYVIQ LLEEALRCPS DGLRKGQALN NLGSVYVDCD  1020
KLDLAADCYM NALNIKHTRA HQGLARVYHL KNQRKAAYNE MTKLIKKAQN NASAFEKRSE  1080
YCDRDMAHGD LGMATQLDPL RTYPYRYRAA VLMDDRKESE AVEEISKAIA FKPDLQLLHL  1140
RAAFFDSMRE SADAIRDCEA ALSLDPSHTD TINLYHKARE PQS

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	61	72	KHRDAERRRRLR

Functional Description ? help Back to Top
Source	Description
UniProt	Essential regulator of the ethylene pathway, which acts by regulating the stability of 1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes. May act as a substrate-specific adapter that connects ACS enzymes, such as ACS5, to ubiquitin ligase complexes, leading to proteasomal degradation of ACS enzymes. {ECO:0000269\|PubMed:15118728, ECO:0000269\|PubMed:16091151, ECO:0000269\|PubMed:18808454}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676755576

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006411032.1	0.0	ethylene-overproduction protein 1
Swissprot	O65020	0.0	ETO1_ARATH; Ethylene-overproduction protein 1
TrEMBL	V4LPM6	0.0	V4LPM6_EUTSA; Uncharacterized protein
STRING	XP_006411032.1	0.0	(Eutrema salsugineum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G38070.1	1e-91	bHLH family protein

Publications ? help Back to Top
Comella P, et al. Fine sequence analysis of 60 kb around the Arabidopsis thaliana AtEm1 locus on chromosome III. Plant Mol. Biol., 1999. 41(5): p. 687-700 [PMID:10645728] Wang KL,Yoshida H,Lurin C,Ecker JR Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein. Nature, 2004. 428(6986): p. 945-50 [PMID:15118728] Gingerich DJ, et al. Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis. J. Biol. Chem., 2005. 280(19): p. 18810-21 [PMID:15749712] Yoshida H,Nagata M,Saito K,Wang KL,Ecker JR Arabidopsis ETO1 specifically interacts with and negatively regulates type 2 1-aminocyclopropane-1-carboxylate synthases. BMC Plant Biol., 2005. 5: p. 14 [PMID:16091151] Christians MJ, et al. The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels. Plant J., 2009. 57(2): p. 332-45 [PMID:18808454] Strader LC,Chen GL,Bartel B Ethylene directs auxin to control root cell expansion. Plant J., 2010. 64(5): p. 874-84 [PMID:21105933] Wang L,Dong J,Gao Z,Liu D The Arabidopsis gene hypersensitive to phosphate starvation 3 encodes ethylene overproduction 1. Plant Cell Physiol., 2012. 53(6): p. 1093-105 [PMID:22623414] Lockhart J Salt of the earth: ethylene promotes salt tolerance by enhancing Na/K homeostasis. Plant Cell, 2013. 25(9): p. 3150 [PMID:24064767] Jiang C,Belfield EJ,Cao Y,Smith JA,Harberd NP An Arabidopsis soil-salinity-tolerance mutation confers ethylene-mediated enhancement of sodium/potassium homeostasis. Plant Cell, 2013. 25(9): p. 3535-52 [PMID:24064768] Yoon GM,Kieber JJ ACC synthase and its cognate E3 ligase are inversely regulated by light. Plant Signal Behav, 2013. 8(12): p. e26478 [PMID:24065059] Woeste KE,Ye C,Kieber JJ Two Arabidopsis mutants that overproduce ethylene are affected in the posttranscriptional regulation of 1-aminocyclopropane-1-carboxylic acid synthase. Plant Physiol., 1999. 119(2): p. 521-30 [PMID:9952448]