PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676751404

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

TCP

Protein Properties

Length: 906aa MW: 99403.2 Da PI: 8.7704

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676751404	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	74	4.5e-23	2	73	28	99
TCP 28 caarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssaseceaesssssasnsssgkaaksaakskk 99 caar+F+L++eLG+++d++tieWLlqqa+pai++ tgt++++a++++ ++ ++ s++ ++ +++ +s 676751404 2 CAARVFQLTRELGHKSDGETIEWLLQQAEPAIIASTGTGTIPANFSTLNATLRGGGGSTIFAQPSKSSSSPL 73 **************************************9999988733333333332333322222222222 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51369	19.692	1	36	IPR017887	Transcription factor TCP subgroup
Pfam	PF03634	2.4E-20	2	90	IPR005333	Transcription factor, TCP

Sequence ? help Back to Top
Protein Sequence Length: 906 aa Download sequence Send to blast
MCAARVFQLT RELGHKSDGE TIEWLLQQAE PAIIASTGTG TIPANFSTLN ATLRGGGGST 60 IFAQPSKSSS SPLSFHSTGM SLYDDSNGTN GSSSSAGVDP SRKLLNTATA AQNAAVFGFH 120 HQMYPPIMST ERNPNPNPSP SPSSMGKAYR EDYFKETEPS GSSQKPGQFQ DQELGPGSGM 180 GRGTANVVPQ PMWAVAPGTT NGGSAFWMLP MSGSGGREQM QQQPGHQMWA FNPGNYPVGT 240 GRVVTAPMGS MMLGGQQLGL GVAESNMAAA MRGGRGGDGL GMTLDQHQHQ HHQQHQETNQ 300 TQASANGGGD DKKYVNMLIF LATWEIFLRF ILITLLRGLT LLQHRTASEG ASVDVKKYLK 360 SSYQSTSALL LGHAMDALLV SPSLEPEKPT TEPASSMANH QPKIKPPTLE KRKLTAKNND 420 KTSFSSHSYS TSNPNSTRWV PRVTHRLRNP TVRLGMARRS IGERQAEALA LPLGMSIAAF 480 TNLVIERTNA AGKNVYVDDL AVISASAIKE SLTNVYGDKL GSFATNFERS FKSTLKILRL 540 INGSQKNSVA GFDLDRSTLE ECSDTELPAK ETSSATSSYE EIQGGPRTTP GGIRTTTLMN 600 DIVLHQETRK LCVVPRSSAM SLDPTERYLE EMARSNDLKC IKIGVSVETN NLMKAKLQKD 660 DSKAAYREQK YKTELEGKKE TDMVQKNEDW LRVSVSFMLA AMLYGTSVFS QQRIKEATSV 720 CEPSEENDSN AWWFPEQLSW LNTEFNIFVC RLRVGFQTFS GVLLFLTFAY IVVQRIPSTK 780 QTIIPFIIIF LALVCGYLGK LCVDTLGGNG NLWLCLWEVF CLLQFLANVF KLALYSFIFC 840 PISVSQGTKP SRWDIMVPYW IRRSFFFGVT WFVLPAITGL LPFATFGELW NHFTVVFVGL 900 VRGYIA

Sequence ? help Back to Top

Protein Sequence Length: 906 aa Download sequence Send to blast

MCAARVFQLT RELGHKSDGE TIEWLLQQAE PAIIASTGTG TIPANFSTLN ATLRGGGGST  60
IFAQPSKSSS SPLSFHSTGM SLYDDSNGTN GSSSSAGVDP SRKLLNTATA AQNAAVFGFH  120
HQMYPPIMST ERNPNPNPSP SPSSMGKAYR EDYFKETEPS GSSQKPGQFQ DQELGPGSGM  180
GRGTANVVPQ PMWAVAPGTT NGGSAFWMLP MSGSGGREQM QQQPGHQMWA FNPGNYPVGT  240
GRVVTAPMGS MMLGGQQLGL GVAESNMAAA MRGGRGGDGL GMTLDQHQHQ HHQQHQETNQ  300
TQASANGGGD DKKYVNMLIF LATWEIFLRF ILITLLRGLT LLQHRTASEG ASVDVKKYLK  360
SSYQSTSALL LGHAMDALLV SPSLEPEKPT TEPASSMANH QPKIKPPTLE KRKLTAKNND  420
KTSFSSHSYS TSNPNSTRWV PRVTHRLRNP TVRLGMARRS IGERQAEALA LPLGMSIAAF  480
TNLVIERTNA AGKNVYVDDL AVISASAIKE SLTNVYGDKL GSFATNFERS FKSTLKILRL  540
INGSQKNSVA GFDLDRSTLE ECSDTELPAK ETSSATSSYE EIQGGPRTTP GGIRTTTLMN  600
DIVLHQETRK LCVVPRSSAM SLDPTERYLE EMARSNDLKC IKIGVSVETN NLMKAKLQKD  660
DSKAAYREQK YKTELEGKKE TDMVQKNEDW LRVSVSFMLA AMLYGTSVFS QQRIKEATSV  720
CEPSEENDSN AWWFPEQLSW LNTEFNIFVC RLRVGFQTFS GVLLFLTFAY IVVQRIPSTK  780
QTIIPFIIIF LALVCGYLGK LCVDTLGGNG NLWLCLWEVF CLLQFLANVF KLALYSFIFC  840
PISVSQGTKP SRWDIMVPYW IRRSFFFGVT WFVLPAITGL LPFATFGELW NHFTVVFVGL  900
VRGYIA

Functional Description ? help Back to Top
Source	Description
UniProt	May play a role in transcriptional processes (PubMed:21875893). Regulates negatively the senescence and chlorotic lesions induced by biotic (e.g. pathogens) and abiotic (e.g. sugars, darkness) agents, probably by controlling programmed cell death (pcd) (PubMed:11846876,PubMed:9338960, Ref.6, PubMed:11728314). Negative regulator of plant programmed cell death (PCD) and effector-triggered immunity (ETI) (PubMed:25455564). Promotes cell division and endoreduplication (e.g. in trichomes) (PubMed:11728314). {ECO:0000269\|PubMed:11728314, ECO:0000269\|PubMed:11846876, ECO:0000269\|PubMed:25455564, ECO:0000269\|PubMed:9338960, ECO:0000269\|Ref.6, ECO:0000305\|PubMed:21875893}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676751404

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013630388.1	0.0	PREDICTED: protein CPR-5
Swissprot	Q9LV85	1e-177	CPR5_ARATH; Protein CPR-5
TrEMBL	A0A087GE79	0.0	A0A087GE79_ARAAL; Uncharacterized protein
STRING	A0A087GE79	0.0	(Arabis alpina)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G72010.1	1e-106	TCP family protein

Publications ? help Back to Top
Clarke JD,Volko SM,Ledford H,Ausubel FM,Dong X Roles of salicylic acid, jasmonic acid, and ethylene in cpr-induced resistance in arabidopsis. Plant Cell, 2000. 12(11): p. 2175-90 [PMID:11090217] Chen Z,Kloek AP,Boch J,Katagiri F,Kunkel BN The Pseudomonas syringae avrRpt2 gene product promotes pathogen virulence from inside plant cells. Mol. Plant Microbe Interact., 2000. 13(12): p. 1312-21 [PMID:11106023] Jirage D, et al. Constitutive salicylic acid-dependent signaling in cpr1 and cpr6 mutants requires PAD4. Plant J., 2001. 26(4): p. 395-407 [PMID:11439127] Clarke JD,Aarts N,Feys BJ,Dong X,Parker JE Constitutive disease resistance requires EDS1 in the Arabidopsis mutants cpr1 and cpr6 and is partially EDS1-dependent in cpr5. Plant J., 2001. 26(4): p. 409-20 [PMID:11439128] Deuschle K, et al. A nuclear gene encoding mitochondrial Delta-pyrroline-5-carboxylate dehydrogenase and its potential role in protection from proline toxicity. Plant J., 2001. 27(4): p. 345-56 [PMID:11532180] Kirik V, et al. CPR5 is involved in cell proliferation and cell death control and encodes a novel transmembrane protein. Curr. Biol., 2001. 11(23): p. 1891-5 [PMID:11728314] Yoshida S,Ito M,Nishida I,Watanabe A Identification of a novel gene HYS1/CPR5 that has a repressive role in the induction of leaf senescence and pathogen-defence responses in Arabidopsis thaliana. Plant J., 2002. 29(4): p. 427-37 [PMID:11846876] Clarke SM,Mur LA,Wood JE,Scott IM Salicylic acid dependent signaling promotes basal thermotolerance but is not essential for acquired thermotolerance in Arabidopsis thaliana. Plant J., 2004. 38(3): p. 432-47 [PMID:15086804] Schenk PM,Kazan K,Rusu AG,Manners JM,Maclean DJ The SEN1 gene of Arabidopsis is regulated by signals that link plant defence responses and senescence. Plant Physiol. Biochem., 2005 Oct-Nov. 43(10-11): p. 997-1005 [PMID:16325410] Heidel AJ,Dong X Fitness benefits of systemic acquired resistance during Hyaloperonospora parasitica infection in Arabidopsis thaliana. Genetics, 2006. 173(3): p. 1621-8 [PMID:16648642] Love AJ, et al. Components of Arabidopsis defense- and ethylene-signaling pathways regulate susceptibility to Cauliflower mosaic virus by restricting long-distance movement. Mol. Plant Microbe Interact., 2007. 20(6): p. 659-70 [PMID:17555274] Aki T, et al. Distinct modulations of the hexokinase1-mediated glucose response and hexokinase1-independent processes by HYS1/CPR5 in Arabidopsis. J. Exp. Bot., 2007. 58(12): p. 3239-48 [PMID:17720689] Jing HC,Anderson L,Sturre MJ,Hille J,Dijkwel PP Arabidopsis CPR5 is a senescence-regulatory gene with pleiotropic functions as predicted by the evolutionary theory of senescence. J. Exp. Bot., 2007. 58(14): p. 3885-94 [PMID:18033818] Brininstool G, et al. Constitutive Expressor Of Pathogenesis-related Genes5 affects cell wall biogenesis and trichome development. BMC Plant Biol., 2008. 8: p. 58 [PMID:18485217] Jing HC, et al. Early leaf senescence is associated with an altered cellular redox balance in Arabidopsis cpr5/old1 mutants. Plant Biol (Stuttg), 2008. 10 Suppl 1: p. 85-98 [PMID:18721314] Fujisaki K,Iwahashi F,Kaido M,Okuno T,Mise K Genetic analysis of a host determination mechanism of bromoviruses in Arabidopsis thaliana. Virus Res., 2009. 140(1-2): p. 103-11 [PMID:19059442] Jing HC,Dijkwel PP CPR5: A Jack of all trades in plants. Plant Signal Behav, 2008. 3(8): p. 562-3 [PMID:19704469] Meng PH, et al. Crosstalks between myo-inositol metabolism, programmed cell death and basal immunity in Arabidopsis. PLoS ONE, 2009. 4(10): p. e7364 [PMID:19812700] Gao G, et al. Arabidopsis CPR5 independently regulates seed germination and postgermination arrest of development through LOX pathway and ABA signaling. PLoS ONE, 2011. 6(4): p. e19406 [PMID:21556325] Trotta A, et al. Regulatory subunit B'gamma of protein phosphatase 2A prevents unnecessary defense reactions under low light in Arabidopsis. Plant Physiol., 2011. 156(3): p. 1464-80 [PMID:21571669] Borghi M,Rus A,Salt DE Loss-of-function of Constitutive Expresser of Pathogenesis Related Genes5 affects potassium homeostasis in Arabidopsis thaliana. PLoS ONE, 2011. 6(10): p. e26360 [PMID:22046278] Orjuela J, et al. A recessive resistance to rice yellow mottle virus is associated with a rice homolog of the CPR5 gene, a regulator of active defense mechanisms. Mol. Plant Microbe Interact., 2013. 26(12): p. 1455-63 [PMID:23944999] Okuma E,Nozawa R,Murata Y,Miura K Accumulation of endogenous salicylic acid confers drought tolerance to Arabidopsis. Plant Signal Behav, 2014. 9(3): p. e28085 [PMID:24603484] Bruggeman Q, et al. The Polyadenylation Factor Subunit CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR30: A Key Factor of Programmed Cell Death and a Regulator of Immunity in Arabidopsis. Plant Physiol., 2014. 165(2): p. 732-746 [PMID:24706550] Bao Z,Hua J Interaction of CPR5 with cell cycle regulators UVI4 and OSD1 in Arabidopsis. PLoS ONE, 2014. 9(6): p. e100347 [PMID:24945150] Meng Z,Ruberti C,Gong Z,Brandizzi F CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses. Plant J., 2017. 89(3): p. 486-501 [PMID:27747970] Wang F, et al. Arabidopsis CPR5 regulates ethylene signaling via molecular association with the ETR1 receptor. J Integr Plant Biol, 2017. 59(11): p. 810-824 [PMID:28708312] Höwing T,Dann M,Hoefle C,Hückelhoven R,Gietl C Involvement of Arabidopsis thaliana endoplasmic reticulum KDEL-tailed cysteine endopeptidase 1 (AtCEP1) in powdery mildew-induced and AtCPR5-controlled cell death. PLoS ONE, 2017. 12(8): p. e0183870 [PMID:28846731] Bowling SA,Clarke JD,Liu Y,Klessig DF,Dong X The cpr5 mutant of Arabidopsis expresses both NPR1-dependent and NPR1-independent resistance. Plant Cell, 1997. 9(9): p. 1573-84 [PMID:9338960]