PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676717988
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family HSF
Protein Properties Length: 407aa    MW: 45677.2 Da    PI: 4.7741
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676717988genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind107.21.3e-33491402102
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k++++++d++l+ +isw  +g sfvv+d+ efa+ +Lp+ Fkh+nf+SFvRQLn+YgF+k+++++         weF+++ F +gkk+ll++i+
     676717988  49 FLSKTFDLVDDPSLDLVISWGLTGASFVVWDPVEFARIILPRNFKHNNFSSFVRQLNTYGFRKIDTDK---------WEFANEAFLRGKKHLLKNIH 136
                   9****************************************************************999.........******************** PP

                   XXXX CS
  HSF_DNA-bind  99 rkks 102
                   r++s
     676717988 137 RRRS 140
                   *987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467851.26E-3244138IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004151.3E-5445138IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.103.2E-3546138IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004472.6E-2949138IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.5E-174972IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.5E-178799IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434088112IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.5E-17100112IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 407 aa     Download sequence    Send to blast
MSPEKDGVSK PTPISIPIST RPESVVDTDV VSPLPMPLDI LHGNPIPPFL SKTFDLVDDP  60
SLDLVISWGL TGASFVVWDP VEFARIILPR NFKHNNFSSF VRQLNTYGFR KIDTDKWEFA  120
NEAFLRGKKH LLKNIHRRRS PQSNQTCSSS SSQSQGSPTE VGEEIEKLRK ERRALMEEMV  180
ELQQQNRGTA RHVDTVNQRL KAAEQRQKQM LSFLAKLFQN PGFLDRLKNL KGGRERGGAL  240
GFEKARKKFI KHQQPQDSST GGEIVKYEAD DWERLLMSEE ETENIPLSSG GMTSSIGVTD  300
PKGKNLMNPS EEEMVDPDYL MPLPTPEGLI KQEETWSVGF DTTIPSFSND DVWGNTMDYN  360
VLEFGSVAET TSGGHLPDVC WEQFAAGVTE TGFNWPTGDD NTPMDDP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A4e-244613817120Heat shock factor protein 1
5d5u_B4e-244613826129Heat shock factor protein 1
5d5v_B4e-244613826129Heat shock factor protein 1
5d5v_D4e-244613826129Heat shock factor protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress response. Activated by DREB2A under heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676717988
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1173180.0AK117318.1 Arabidopsis thaliana At5g03720 mRNA for putative heat shock transcription factor, complete cds, clone: RAFL16-88-H09.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002873110.10.0heat stress transcription factor A-3
SwissprotQ8GYY10.0HSFA3_ARATH; Heat stress transcription factor A-3
TrEMBLD7LWT00.0D7LWT0_ARALL; AT-HSFA3
STRINGscaffold_600303.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM109502529
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03720.10.0heat shock transcription factor A3
Publications ? help Back to Top
  1. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nie S,Yue H,Xing D
    A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.
    Plant Physiol., 2016.
    [PMID:26099269]
  4. Hu Z, et al.
    Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.
    Plant J., 2015. 84(6): p. 1178-91
    [PMID:26576681]
  5. Song C,Chung WS,Lim CO
    Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis.
    Mol. Cells, 2016. 39(6): p. 477-83
    [PMID:27109422]
  6. Kim GD,Cho YH,Lee BH,Yoo SD
    STABILIZED1 Modulates Pre-mRNA Splicing for Thermotolerance.
    Plant Physiol., 2017. 173(4): p. 2370-2382
    [PMID:28223317]
  7. Song C,Lee J,Kim T,Hong JC,Lim CO
    VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis.
    Planta, 2018. 247(6): p. 1439-1448
    [PMID:29536220]