PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_011071286.1

Organism

Sesamum indicum

Taxonomic ID

4182

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

C2H2

Protein Properties

Length: 663aa MW: 73731.6 Da PI: 6.904

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011071286.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.8	0.00035	73	95	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C k+F ++ L H++ H XP_011071286.1 73 FECGYCFKVFANSQALGGHQNAH 95 89******************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.91E-6	69	100	No hit	No description
Gene3D	G3DSA:3.30.160.60	3.7E-4	70	99	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.157	73	100	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	75	95	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.40.630.10	6.2E-103	273	440	No hit	No description
SuperFamily	SSF53187	2.86E-83	273	459	No hit	No description
CDD	cd08017	0	278	653	No hit	No description
TIGRFAMs	TIGR01891	4.8E-115	280	641	IPR017439	Amidohydrolase
Pfam	PF01546	6.3E-31	335	648	IPR002933	Peptidase M20
SuperFamily	SSF55031	1.07E-26	443	562	IPR011650	Peptidase M20, dimerisation domain
Gene3D	G3DSA:3.30.70.360	6.4E-40	443	561	IPR011650	Peptidase M20, dimerisation domain
Pfam	PF07687	8.4E-9	444	542	IPR011650	Peptidase M20, dimerisation domain
Gene3D	G3DSA:3.40.630.10	6.2E-103	562	653	No hit	No description
SuperFamily	SSF53187	2.86E-83	564	653	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008152	Biological Process	metabolic process
GO:0003676	Molecular Function	nucleic acid binding
GO:0016787	Molecular Function	hydrolase activity
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 663 aa Download sequence Send to blast
MEGICISRVH EEYTEKSTTE KKLKLFGIEL DSSSHEAHKG LPEVGEESIN SSASGSGKSS 60 GDGDHRMAEE KKFECGYCFK VFANSQALGG HQNAHKKERM RKKRLQLQAR KASINYYIQP 120 YYNSHKNINV NTCSDYYGSN VNPAWIYDPS PNQIISFGPY GPDPDMNGSN VLRWDVDELP 180 ADRVPFRHDA HRFSLTEVDR SSREKSRPLM TCKSSSLPNS KKSLLLIFNV VSLFPFMQLI 240 ASRSSDRYCF NPFLHQHNAS LTDYVKELAN EPETLNWLKN IRREIHKNPE LAFQEFNTSA 300 LVRLELEKMG VRYRWPVART GVVAAIGTGA PPFVALRADM DALPIQEMRE WEHKSQIDGK 360 MHACGHDAHV AMLLGAAKIL QELSNYLHGT VILIFQPAEE NGEGAKEMIR EGVLDNVSAI 420 LGLHTVHKYP SGTVASRPGQ FLAGCGSFKA VIRGKGGHAA APHNSVDPIL AASVSISSLQ 480 SIVSRELDPM DSQVVSVTTV RGGSGFDVIP ESATIAGTFR AFGRESFCAL RKRIEEVIDG 540 QAAVHRCLAD IEFDGKDHPT LPPTINDERI YKHVEQVSRM VVGEETTLLA PHFMGSEDFA 600 VYMERVAGTF LLLGVRNEKV GSVYPPHSPY YTIDEDVLPI GATIHATFAF SYLLTFHDHC 660 RLL

Sequence ? help Back to Top

Protein Sequence Length: 663 aa Download sequence Send to blast

MEGICISRVH EEYTEKSTTE KKLKLFGIEL DSSSHEAHKG LPEVGEESIN SSASGSGKSS  60
GDGDHRMAEE KKFECGYCFK VFANSQALGG HQNAHKKERM RKKRLQLQAR KASINYYIQP  120
YYNSHKNINV NTCSDYYGSN VNPAWIYDPS PNQIISFGPY GPDPDMNGSN VLRWDVDELP  180
ADRVPFRHDA HRFSLTEVDR SSREKSRPLM TCKSSSLPNS KKSLLLIFNV VSLFPFMQLI  240
ASRSSDRYCF NPFLHQHNAS LTDYVKELAN EPETLNWLKN IRREIHKNPE LAFQEFNTSA  300
LVRLELEKMG VRYRWPVART GVVAAIGTGA PPFVALRADM DALPIQEMRE WEHKSQIDGK  360
MHACGHDAHV AMLLGAAKIL QELSNYLHGT VILIFQPAEE NGEGAKEMIR EGVLDNVSAI  420
LGLHTVHKYP SGTVASRPGQ FLAGCGSFKA VIRGKGGHAA APHNSVDPIL AASVSISSLQ  480
SIVSRELDPM DSQVVSVTTV RGGSGFDVIP ESATIAGTFR AFGRESFCAL RKRIEEVIDG  540
QAAVHRCLAD IEFDGKDHPT LPPTINDERI YKHVEQVSRM VVGEETTLLA PHFMGSEDFA  600
VYMERVAGTF LLLGVRNEKV GSVYPPHSPY YTIDEDVLPI GATIHATFAF SYLLTFHDHC  660
RLL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1xmb_A	1e-153	251	653	3	402	IAA-amino acid hydrolase homolog 2
2q43_A	1e-153	251	653	3	402	IAA-amino acid hydrolase ILR1-like 2
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Hydrolyzes certain amino acid conjugates of the plant growth regulator indole-3-acetic acid (IAA), including IAA-Ala, IAA-Leu, IAA-Met, IAA-Phe, IAA-Ser, IAA-Thr, IAA-Tyr and IAA-Val (PubMed:11923288). Is the most efficient enzyme of the ILL family for IAA-Ala (PubMed:11923288). Not important for IAA-Leu hydrolysis in roots (PubMed:15155875). May act with ILR1 to provide free IAA to germinating seedlings (PubMed:15155875). {ECO:0000269\|PubMed:11923288, ECO:0000269\|PubMed:15155875}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011071286.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020547648.1	0.0	IAA-amino acid hydrolase ILR1-like 2 isoform X1
Swissprot	P54970	1e-152	ILL2_ARATH; IAA-amino acid hydrolase ILR1-like 2
TrEMBL	A0A2G9HUS9	0.0	A0A2G9HUS9_9LAMI; Aminoacylase ACY1
STRING	XP_009613546.1	0.0	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G10480.1	2e-13	zinc finger protein 5

Publications ? help Back to Top
Davies RT,Goetz DH,Lasswell J,Anderson MN,Bartel B IAR3 encodes an auxin conjugate hydrolase from Arabidopsis. Plant Cell, 1999. 11(3): p. 365-76 [PMID:10072397] LeClere S,Tellez R,Rampey RA,Matsuda SP,Bartel B Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis. J. Biol. Chem., 2002. 277(23): p. 20446-52 [PMID:11923288] Sokolenko A, et al. The gene complement for proteolysis in the cyanobacterium Synechocystis sp. PCC 6803 and Arabidopsis thaliana chloroplasts. Curr. Genet., 2002. 41(5): p. 291-310 [PMID:12185496] Rampey RA, et al. A family of auxin-conjugate hydrolases that contributes to free indole-3-acetic acid levels during Arabidopsis germination. Plant Physiol., 2004. 135(2): p. 978-88 [PMID:15155875] Schuller A,Ludwig-Müller J A family of auxin conjugate hydrolases from Brassica rapa: characterization and expression during clubroot disease. New Phytol., 2006. 171(1): p. 145-57 [PMID:16771990] Levin EJ,Kondrashov DA,Wesenberg GE,Phillips GN Ensemble refinement of protein crystal structures: validation and application. Structure, 2007. 15(9): p. 1040-52 [PMID:17850744] Bitto E, et al. X-ray structure of ILL2, an auxin-conjugate amidohydrolase from Arabidopsis thaliana. Proteins, 2009. 74(1): p. 61-71 [PMID:18543330] Sanchez Carranza AP, et al. Hydrolases of the ILR1-like family of Arabidopsis thaliana modulate auxin response by regulating auxin homeostasis in the endoplasmic reticulum. Sci Rep, 2016. 6: p. 24212 [PMID:27063913] Bartel B,Fink GR ILR1, an amidohydrolase that releases active indole-3-acetic acid from conjugates. Science, 1995. 268(5218): p. 1745-8 [PMID:7792599]