PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_08538.1_g00001.1
Organism
Raphanus sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family MYB_related
Protein Properties Length: 335aa    MW: 37872.6 Da    PI: 6.1819
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_08538.1_g00001.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding41.92.2e-1394135144
                              TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
          Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                              r +++++E+   +++ +++G++ W++Ia +++ gRt++++k++w
  Rsa1.0_08538.1_g00001.1  94 RCKFSADEERTVIELQAEFGNK-WARIATYLP-GRTDNDVKNFW 135
                              679*******************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.609.1E-6429IPR009057Homeodomain-like
PROSITE profilePS500904.484629IPR017877Myb-like domain
SMARTSM00717171088IPR001005SANT/Myb domain
SuperFamilySSF466892.65E-1182146IPR009057Homeodomain-like
PROSITE profilePS5129418.38391143IPR017930Myb domain
SMARTSM007172.2E-1293141IPR001005SANT/Myb domain
PfamPF002491.9E-1294135IPR001005SANT/Myb domain
CDDcd001671.92E-1096135No hitNo description
Gene3DG3DSA:1.10.10.603.4E-1696139IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 335 aa     Download sequence    Send to blast
MDASKKEEIK KGPWKAEEDQ VLINHVNRYT VRVTGVPFDP KVFFNAPANH AVSVGSTNSV  60
PISKSIQLYP FPRLLLLVLQ SWFRLLRPYG FFSRCKFSAD EERTVIELQA EFGNKWARIA  120
TYLPGRTDND VKNFWSSRIK RLARILRNSS DASSSSNPKP SSHRNKGKNV KPIQSLYATQ  180
FQRFGLVEEE ITAPCSSSKI LPYSSSDQND HEALRLPELG IKLEHKPLDL VLAETAATPL  240
MSEFHNANQQ AVNSNSFSSE SIELLARLDN PYYYDILGPA DSSEPLFVLP QPVFEPSPMP  300
RSCSRHVSKD DEADVFLDDF PEDMFDQVDY SNPSP
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_08538.1_g00001.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAL1386464e-61AL138646.2 Arabidopsis thaliana DNA chromosome 3, BAC clone T8B10.
GenBankCP0026864e-61CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022572064.11e-124transcription factor DUO1-like
SwissprotA0A178VEK71e-112DUO1_ARATH; Transcription factor DUO1
TrEMBLA0A0D3CUY61e-126A0A0D3CUY6_BRAOL; Uncharacterized protein
STRINGBo6g077030.11e-127(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM65512842
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.11e-113MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]