PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_03058.1_g00002.1
Organism
Raphanus sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 362aa    MW: 40758.1 Da    PI: 9.3913
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_03058.1_g00002.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP65.19.5e-212388171
                  E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                             rkeksL++l ++f+kl+++++ +   ++e+a +L    v  +rRRiYD++N+Le+++++++k k+ ++w+g
  Rsa1.0_03058.1_g00002.1 23 RKEKSLGVLVSNFMKLYNRADVDLFGIDEAAAKL---GV--ERRRIYDVVNILESIGVVARKGKSLYSWNG 88
                             79********************************...**..****************************98 PP
2E2F_TDP83.71.4e-26151231171
                  E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                              +ke+sL+ll+q+f+k++ +s+++i+tl+++ak+L+++     ++k+k+RR+YDi+NVL++++liek     ++k++++w g
  Rsa1.0_03058.1_g00002.1 151 KKERSLWLLSQNFVKMFLCSHDEIITLDTAAKALLNDsqdsvQMKTKVRRLYDIANVLSSMELIEKthipgTRKPAYKWLG 231
                              699****************************************************************************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.6E-222089IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.08E-152286IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.2E-252388IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.5E-172488IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.109.5E-23149233IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.7E-33151231IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.9E-21152231IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.85E-13154232IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 362 aa     Download sequence    Send to blast
MEKMSWIVSS QDVDALALQS YSRKEKSLGV LVSNFMKLYN RADVDLFGID EAAAKLGVER  60
RRIYDVVNIL ESIGVVARKG KSLYSWNGFV HIPRSLLQLK EEGLREGFGL STICSNSHKV  120
SHDGSDESDD SLSLQPDDQD KSSSLSTMDH KKERSLWLLS QNFVKMFLCS HDEIITLDTA  180
AKALLNDSQD SVQMKTKVRR LYDIANVLSS MELIEKTHIP GTRKPAYKWL GSKSLIEKGS  240
TLFNSTDESK KRVFGTEITN LSTKRNKTDC SSNYVLQTGY KKHDEETKPA AKSSYMFGPF  300
SPTAASKKKK NNNVGTIYNG RLQDLEALSS TYKPQYSNQD VTGLLGHYTG SWNKWFAELD  360
RK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A7e-34222233228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_03058.1_g00002.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018488873.10.0PREDICTED: E2F transcription factor-like E2FF
SwissprotQ8RWL01e-167E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A0D3CNF00.0A0A0D3CNF0_BRAOL; Uncharacterized protein
TrEMBLA0A3P6ERE50.0A0A3P6ERE5_BRAOL; Uncharacterized protein
STRINGBo5g155250.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-159DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]