PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_00180.1_g00020.1
Organism
Raphanus sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family HSF
Protein Properties Length: 407aa    MW: 45875.5 Da    PI: 4.6998
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_00180.1_g00020.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind107.31.2e-33521432102
                              HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXX CS
             HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFk 87 
                              Fl+k++++++d++l+ +isw  +g sfvv+d+ efa+ +Lp+ Fkh+nf+SFvRQLn+YgF+k+++++         weF+++ F 
  Rsa1.0_00180.1_g00020.1  52 FLSKTFDLVDDPSLDPVISWGLTGASFVVWDPVEFARIILPRNFKHNNFSSFVRQLNTYGFRKIDTDK---------WEFANEAFL 128
                              9****************************************************************999.........********* PP

                              XXXXXXXXXXXXXXX CS
             HSF_DNA-bind  88 kgkkellekikrkks 102
                              +g+k+ll++i+r++s
  Rsa1.0_00180.1_g00020.1 129 RGRKHLLKNIHRRRS 143
                              ************987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467859.07E-3447141IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004158.0E-5648141IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.101.6E-3549141IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000561.2E-175275IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004471.2E-2952141IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.2E-1790102IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434091115IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.2E-17103115IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 407 aa     Download sequence    Send to blast
MRPEKDGVSK PTPLSIPIST RPESIPLHVD ADVTSPLPMP LDILHGNPIP PFLSKTFDLV  60
DDPSLDPVIS WGLTGASFVV WDPVEFARII LPRNFKHNNF SSFVRQLNTY GFRKIDTDKW  120
EFANEAFLRG RKHLLKNIHR RRSPQSNQAC SSNSQSLGSP TEVGEELEKL RKERRALMEE  180
MVELQQQNRG TARHVDTVNQ RLKAAEQRQK QMLSFLAKLF QNPGFLDRLK NLKGEGGGGA  240
LGFGKARKKF IKHSPTEGEI VKYEADDWER LLMSEEETEN VPLSSQGMMT STDPKGKNLM  300
NPSEEEEEEE MMNQDYLMSF PAPPEGVIKQ EETTWSMGFD TTTIPSFSNE DVWGNTMDYN  360
VSEFGSVAET TSGGCLPDVC WEQFAAGMTE TGFNWPPGDD TTPMDDH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A4e-244914617125Heat shock factor protein 1
5d5u_B4e-244914126129Heat shock factor protein 1
5d5v_B4e-244914126129Heat shock factor protein 1
5d5v_D4e-244914126129Heat shock factor protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress response. Activated by DREB2A under heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_00180.1_g00020.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1173181e-172AK117318.1 Arabidopsis thaliana At5g03720 mRNA for putative heat shock transcription factor, complete cds, clone: RAFL16-88-H09.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018445490.10.0PREDICTED: heat stress transcription factor A-3
SwissprotQ8GYY10.0HSFA3_ARATH; Heat stress transcription factor A-3
TrEMBLA0A078FAB70.0A0A078FAB7_BRANA; BnaCnng02620D protein
TrEMBLA0A0D3EI360.0A0A0D3EI36_BRAOL; Uncharacterized protein
TrEMBLA0A3P6EQ720.0A0A3P6EQ72_BRAOL; Uncharacterized protein
STRINGBo9g181780.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM109502529
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03720.10.0heat shock transcription factor A3
Publications ? help Back to Top
  1. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nie S,Yue H,Xing D
    A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.
    Plant Physiol., 2016.
    [PMID:26099269]
  4. Hu Z, et al.
    Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.
    Plant J., 2015. 84(6): p. 1178-91
    [PMID:26576681]
  5. Song C,Chung WS,Lim CO
    Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis.
    Mol. Cells, 2016. 39(6): p. 477-83
    [PMID:27109422]
  6. Kim GD,Cho YH,Lee BH,Yoo SD
    STABILIZED1 Modulates Pre-mRNA Splicing for Thermotolerance.
    Plant Physiol., 2017. 173(4): p. 2370-2382
    [PMID:28223317]
  7. Song C,Lee J,Kim T,Hong JC,Lim CO
    VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis.
    Planta, 2018. 247(6): p. 1439-1448
    [PMID:29536220]