PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 30167.m000852
Common NameLOC8272350, RCOM_1568280
Organism
Ricinus communis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae; Ricinus
Family MYB
Protein Properties Length: 344aa    MW: 39485.6 Da    PI: 9.092
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
30167.m000852genomeJCVIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding47.44.6e-15453148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT..TTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmg..kgRtlkqcksrwqkyl 48
                     r+rW +eEd ll+ +vkq+G++ W++I+++m    +R +k+c +rw +yl
    30167.m000852  4 RQRWQPEEDALLKAYVKQYGPKEWNLISQRMSkpINRDPKSCLERWKNYL 53
                     89********************************99************97 PP
2Myb_DNA-binding35.22.8e-1159103147
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                      +g+ T+eE+ l + + +++G++ Wk+Ia++++ gRt+k +  +w  +
    30167.m000852  59 KGSLTPEEQALVISLQAKYGNK-WKKIASEVP-GRTAKRLGKWWEVF 103
                      6788******************.*********.*****999999766 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129423.227157IPR017930Myb domain
SMARTSM007177.0E-14355IPR001005SANT/Myb domain
SuperFamilySSF466898.07E-23498IPR009057Homeodomain-like
CDDcd001671.11E-7653No hitNo description
Gene3DG3DSA:1.10.10.602.5E-21660IPR009057Homeodomain-like
PfamPF139218.8E-15768No hitNo description
PROSITE profilePS5129418.23158108IPR017930Myb domain
SMARTSM007173.6E-1058106IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.605.1E-1661107IPR009057Homeodomain-like
CDDcd001672.24E-563104No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 344 aa     Download sequence    Send to blast
MKERQRWQPE EDALLKAYVK QYGPKEWNLI SQRMSKPINR DPKSCLERWK NYLKPGIKKG  60
SLTPEEQALV ISLQAKYGNK WKKIASEVPG RTAKRLGKWW EVFKEKQLKI KNSDQHQQHK  120
DINNNNNNNN NNNSSSIIPE CRYDHILETF AEKYVQPKLV HFQSSSSSSA SSFSLMPDPS  180
PDPDPTPDPV LSLGSVWMNA ESSLSSSATT STVSAAMGTL VQYCKELEEA RQSWMQHKKE  240
ATWRLCRLEQ QLESEKARKK REKLEEIEAK IRCLREEEMA FMSWIENDYR EQLSTLQRDA  300
ESKEGKLVEA WCSKHSKLVE LIGVHYSGDG TATTAATGTS VGRF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3zqc_A4e-1511100995MYB3
3zqc_D4e-1511100995MYB3
3zqc_G4e-1511100995MYB3
3zqc_J4e-1511100995MYB3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1257262RKKREK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11076771, PubMed:11140682, PubMed:11882937, PubMed:12750468, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509, PubMed:23271976). Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development (PubMed:23271976). LBD6 is required for this binding (PubMed:23271976). Positive regulator of flowering that binds to the promoter of FT (PubMed:21950734). Regulates FT expression by forming a functional complex with CO (PubMed:21950734). Involved in leaf polarity establishment by functioning cooperatively with NUCL1 to repress abaxial genes ARF3, ARF4, KAN1, KAN2, YAB1 and YAB5, and the knox homeobox genes KNAT1, KNAT2, KNAT6, and STM to promote adaxial development in leaf primordia at shoot apical meristems at high temperatures (PubMed:27334696). {ECO:0000269|PubMed:11076771, ECO:0000269|PubMed:11140682, ECO:0000269|PubMed:11882937, ECO:0000269|PubMed:12750468, ECO:0000269|PubMed:16006579, ECO:0000269|PubMed:16699177, ECO:0000269|PubMed:17395603, ECO:0000269|PubMed:17559509, ECO:0000269|PubMed:23271976, ECO:0000269|PubMed:27334696}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap30167.m000852
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with an afternoon peak in long days and with a broad night peak in short days (PubMed:21950734). Expression of AS1 in stem cells of the shoot apical meristem is prevented by SHOOT MERISTEMLESS (STM). Expression is activated by GTE6 during leaf morphogenesis (PubMed:16166385). {ECO:0000269|PubMed:16166385, ECO:0000269|PubMed:21950734}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002521197.10.0transcription factor AS1
SwissprotO809312e-98AS1_ARATH; Transcription factor AS1
TrEMBLB9S5C80.0B9S5C8_RICCO; Asymmetric leaves1 and rough sheath, putative
STRINGXP_002521197.10.0(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF25973369
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G37630.13e-62MYB family protein
Publications ? help Back to Top
  1. Hazen SP, et al.
    Rapid array mapping of circadian clock and developmental mutations in Arabidopsis.
    Plant Physiol., 2005. 138(2): p. 990-7
    [PMID:15908595]
  2. Pinon V, et al.
    Three PIGGYBACK genes that specifically influence leaf patterning encode ribosomal proteins.
    Development, 2008. 135(7): p. 1315-24
    [PMID:18305008]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Zhou F,Roy B,Dunlap JR,Enganti R,von Arnim AG
    Translational control of Arabidopsis meristem stability and organogenesis by the eukaryotic translation factor eIF3h.
    PLoS ONE, 2014. 9(4): p. e95396
    [PMID:24736281]
  5. Scofield S,Dewitte W,Murray JA
    STM sustains stem cell function in the Arabidopsis shoot apical meristem and controls KNOX gene expression independently of the transcriptional repressor AS1.
    Plant Signal Behav, 2018.
    [PMID:24776954]
  6. Ivanova A, et al.
    A Functional Antagonistic Relationship between Auxin and Mitochondrial Retrograde Signaling Regulates Alternative Oxidase1a Expression in Arabidopsis.
    Plant Physiol., 2014. 165(3): p. 1233-1254
    [PMID:24820025]
  7. Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y
    The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis.
    Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71
    [PMID:26108442]
  8. Kaurilind E,Xu E,Brosché M
    A genetic framework for H2O2 induced cell death in Arabidopsis thaliana.
    BMC Genomics, 2015. 16: p. 837
    [PMID:26493993]
  9. Mateo-Bonmatí E, et al.
    Plastid control of abaxial-adaxial patterning.
    Sci Rep, 2015. 5: p. 15975
    [PMID:26522839]
  10. Rast-Somssich MI, et al.
    Alternate wiring of a KNOXI genetic network underlies differences in leaf development of A. thaliana and C. hirsuta.
    Genes Dev., 2015. 29(22): p. 2391-404
    [PMID:26588991]
  11. Guzmán-López JA,Abraham-Juárez MJ,Lozano-Sotomayor P,de Folter S,Simpson J
    Arabidopsis thaliana gonidialess A/Zuotin related factors (GlsA/ZRF) are essential for maintenance of meristem integrity.
    Plant Mol. Biol., 2016. 91(1-2): p. 37-51
    [PMID:26826012]
  12. Li Z, et al.
    Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis.
    J Integr Plant Biol, 2016. 58(12): p. 959-970
    [PMID:27273574]
  13. Matsumura Y, et al.
    A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis.
    Biol Open, 2016. 5(7): p. 942-54
    [PMID:27334696]
  14. Silverblatt-Buser EW,Frick MA,Rabeler C,Kaplinsky NJ
    Genetic Interactions Between BOB1 and Multiple 26S Proteasome Subunits Suggest a Role for Proteostasis in Regulating Arabidopsis Development.
    G3 (Bethesda), 2018. 8(4): p. 1379-1390
    [PMID:29487187]
  15. Tsukaya H,Uchimiya H
    Genetic analyses of the formation of the serrated margin of leaf blades in Arabidopsis: combination of a mutational analysis of leaf morphogenesis with the characterization of a specific marker gene expressed in hydathodes and stipules.
    Mol. Gen. Genet., 1997. 256(3): p. 231-8
    [PMID:9393447]